{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T09:29:07Z","timestamp":1771666147501,"version":"3.50.1"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2013,1]]},"abstract":"<jats:sec>\n            <jats:title>Purpose:<\/jats:title>\n            <jats:p>To describe the features of sequential spectral-domain optical coherence tomography (OCT) images in an eye with acute primary toxoplasmosis.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Case report of an individual diagnosed with acute primary toxoplasmic retinochoroiditis. Initial and follow-up spectral-domain OCT findings are described.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>This patient developed retinitis as a result of an acute infection consistent with <jats:italic toggle=\"yes\">Toxoplasma gondii<\/jats:italic> suggested by toxoplasma-specific IgM serology and the response to therapy. The retinitis appeared initially as a hyperreflective region on spectral-domain OCT. An intraretinal cyst consistent with <jats:italic toggle=\"yes\">T. gondii<\/jats:italic> parasitic infection was identified. Subsequent OCT images demonstrated progression to full-thickness retinal necrosis with the development of cystic spaces in the retina.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>Optical coherence tomography may be useful in characterizing the features, extent, and location of retinitis caused by <jats:italic toggle=\"yes\">T. gondii<\/jats:italic>. Specific OCT features may indicate whether the infection is acute phase or becoming quiescent.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/icb.0b013e31826f093b","type":"journal-article","created":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T02:55:02Z","timestamp":1349060102000},"page":"98-101","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":14,"title":["SEQUENTIAL OPTICAL COHERENCE TOMOGRAPHY IMAGES OF RETINAL NECROSIS IN ACUTE OCULAR TOXOPLASMOSIS"],"prefix":"10.1097","volume":"7","author":[{"given":"Ahmad A.","family":"Alwassia","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyung","family":"Cho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehreen","family":"Adhi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jay S.","family":"Duker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Caroline R.","family":"Baumal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-27-20240721","doi-asserted-by":"crossref","first-page":"40","DOI":"10.3109\/08820539309060209","article-title":"Ocular toxoplasmosis: pathogenesis, diagnosis, and management.","volume":"8","author":"Pierce","year":"1993","journal-title":"Semin Ophthalmol"},{"key":"R2-27-20240721","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1097\/IIO.0b013e31822d663b","article-title":"Ocular toxoplasmosis: advances in detection and treatment.","volume":"51","author":"Englander","year":"2011","journal-title":"Int Ophthalmol Clin"},{"key":"R3-27-20240721","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1016\/S0140-6736(04)16412-X","article-title":"Toxoplasmosis.","volume":"363","author":"Montoya","year":"2004","journal-title":"Lancet"},{"key":"R4-27-20240721","doi-asserted-by":"crossref","first-page":"58","DOI":"10.3341\/kjo.2012.26.1.58","article-title":"A case of ocular toxoplasmosis imaged with spectral domain optical coherence tomography.","volume":"26","author":"Cho","year":"2012","journal-title":"Korean J Ophthalmol"},{"key":"R5-27-20240721","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.ajo.2006.03.037","article-title":". Third-generation optical coherence tomography findings in punctate retinal toxoplasmosis.","volume":"142","author":"Orefice","year":"2006","journal-title":"Am J Ophthalmol"},{"key":"R6-27-20240721","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1136\/bjo.2006.108068","article-title":". Vitreoretinal morphology in active ocular toxoplasmosis: a prospective study by optical coherence tomography.","volume":"91","author":"Orefice","year":"2007","journal-title":"Br J Ophthalmol"}],"container-title":["RETINAL Cases &amp; Brief Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/01271216-201300710-00027","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T08:01:09Z","timestamp":1721548869000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01271216-201300710-00027"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,1]]},"references-count":6,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1097\/icb.0b013e31826f093b","relation":{},"ISSN":["1935-1089"],"issn-type":[{"value":"1935-1089","type":"print"}],"subject":[],"published":{"date-parts":[[2013,1]]}}}