{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T12:35:04Z","timestamp":1768826104005,"version":"3.49.0"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,9]]},"DOI":"10.1097\/icl.0b013e318184bdb6","type":"journal-article","created":{"date-parts":[[2008,9,1]],"date-time":"2008-09-01T07:08:02Z","timestamp":1220252882000},"page":"287-292","source":"Crossref","is-referenced-by-count":11,"title":["Topical Apolipoprotein A-1 May Have a Beneficial Effect on the Corneal Epithelium in a Mouse Model of Dry Eye: A Pilot Study"],"prefix":"10.1097","volume":"34","author":[{"given":"Aung Kyaw","family":"Nyunt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yong","family":"Yu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoichi","family":"Shimada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-7-20210128","first-page":"221","article-title":"Report of the National Eye Institute\/Industry workshop on Clinical Trials in Dry Eyes.","volume":"21","author":"Lemp","year":"1995","journal-title":"CLAO J"},{"key":"R2-7-20210128","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/S0002-9394(14)71688-5","article-title":"Prevalence of dry eye among the elderly.","volume":"124","author":"Schein","year":"1997","journal-title":"Am J Ophthalmol"},{"key":"R3-7-20210128","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1007\/BF00404705","article-title":"Prevalence of dry eye in Japanese eye centers.","volume":"233","author":"Hikichi","year":"1995","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"R4-7-20210128","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1097\/00003226-200009000-00018","article-title":"Twenty-five years of contact lenses: The impact on the cornea and ophthalmic practice.","volume":"19","author":"McMahon","year":"2000","journal-title":"Cornea"},{"key":"R5-7-20210128","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1016\/j.ophtha.2003.07.008","article-title":"Sequential changes of lipid tear film after the instillation of a single drop of a new emulsion eye drop in dry eye patients.","volume":"111","author":"Di Pascuale","year":"2004","journal-title":"Ophthalmology"},{"key":"R6-7-20210128","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/S0002-9394(14)70378-2","article-title":"Correlation of tear lipid layer interference patterns with the diagnosis and severity of dry eye.","volume":"122","author":"Yokoi","year":"1996","journal-title":"Am J Ophthalmol"},{"key":"R7-7-20210128","doi-asserted-by":"crossref","first-page":"5772","DOI":"10.1074\/jbc.270.11.5772","article-title":"Cell toxicity induced by inhibition of acyl coenzyme A:cholesterol acyltransferase and accumulation of unesterified cholesterol.","volume":"270","author":"Warner","year":"1995","journal-title":"J Biol Chem"},{"key":"R8-7-20210128","doi-asserted-by":"crossref","first-page":"21324","DOI":"10.1074\/jbc.M002541200","article-title":"Absence of ACAT-1 attenuates atherosclerosis but causes dry eye and cutaneous xanthomatosis in mice with congenital hyperlipidemia.","volume":"275","author":"Yagyu","year":"2000","journal-title":"J Biol Chem"},{"key":"R9-7-20210128","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1097\/00004397-197301310-00004","article-title":"Lecithin agar for detection of microbial phospholipases.","volume":"13","author":"Andrews","year":"1973","journal-title":"Int Ophthalmol Clin"},{"key":"R10-7-20210128","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1001\/archopht.1969.00990020539019","article-title":"The oils of the meibomian glands. Physical and surface characteristics.","volume":"82","author":"Brown","year":"1969","journal-title":"Arch Ophthalmol"},{"key":"R11-7-20210128","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1001\/archopht.118.9.1264","article-title":"Prevalence of and risk factors for dry eye syndrome.","volume":"118","author":"Moss","year":"2000","journal-title":"Arch Ophthalmol"},{"key":"R12-7-20210128","doi-asserted-by":"crossref","first-page":"1313","DOI":"10.1038\/82110","article-title":"Cholesterol esters and atherosclerosis\u2014A game of ACAT and mouse.","volume":"12","author":"Rudel","year":"2000","journal-title":"Nat Med"},{"key":"R13-7-20210128","first-page":"630","article-title":"Lipoprotein changes induced by pantethine in hyperlipoproteinemic patients: Adults and children.","volume":"24","author":"Bertolini","year":"1986","journal-title":"Int J Clin Pharmacol Ther Toxicol"},{"key":"R14-7-20210128","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/0021-9150(82)90191-5","article-title":"Effect of pantethine on lipoprotein profiles and HDL subfractions in experimentally hypercholesterolemic rabbits.","volume":"41","author":"Tomikawa","year":"1982","journal-title":"Atherosclerosis"},{"key":"R15-7-20210128","first-page":"84","article-title":"Clinical study of the effectiveness of a dexpanthenol containing artificial tears solution (Siccaprotect) in treatment of dry eyes.","volume":"209","author":"Gobbels","year":"1996","journal-title":"Klin Monatsbl Augenheilkd"},{"key":"R16-7-20210128","doi-asserted-by":"crossref","first-page":"4293","DOI":"10.1167\/iovs.03-1145","article-title":"Experimental dry eye stimulates production of inflammatory cytokines and MMP-9 and activates MAPK signaling pathways on the ocular surface.","volume":"45","author":"Luo","year":"2004","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R17-7-20210128","first-page":"632","article-title":"A mouse model of keratoconjunctivitis sicca.","volume":"43","author":"Dursun","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R18-7-20210128","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1167\/iovs.05-0380","article-title":"Botulinum toxin B-induced mouse model of keratoconjunctivitis sicca.","volume":"47","author":"Suwan-apichon","year":"2006","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R19-7-20210128","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1167\/iovs.04-1344","article-title":"d-{beta}-hydroxybutyrate protects against corneal epithelial disorders in a rat dry eye model with jogging board.","volume":"46","author":"Nakamura","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R20-7-20210128","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/S0161-6420(99)90171-9","article-title":"Topical nonpreserved methylprednisolone therapy for keratoconjunctivitis sicca in Sjogren syndrome.","volume":"106","author":"Marsh","year":"1999","journal-title":"Ophthalmology"},{"key":"R21-7-20210128","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/S0161-6420(99)00176-1","article-title":"Two, multicenter, randomized studies of the efficacy and safety of cyclosporin ophthalmic emulsion in moderate to severe dry eye.","volume":"107","author":"Sall","year":"2000","journal-title":"Ophthalmology"},{"key":"R22-7-20210128","first-page":"2283","article-title":"Pro- and anti-inflammatory forms of interleukin-1 in the tear fluid and conjunctiva of patients with dry-eye disease.","volume":"42","author":"Solomon","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R23-7-20210128","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/j.exer.2006.02.004","article-title":"Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye.","volume":"83","author":"De Paiva","year":"2006","journal-title":"Exp Eye Res"},{"key":"R24-7-20210128","doi-asserted-by":"crossref","first-page":"2381","DOI":"10.1182\/blood.V97.8.2381","article-title":"Apolipoprotein A-I inhibits the production of interleukin-1beta and tumor necrosis factor-alpha by blocking contact-mediated activation of monocytes by T lymphocytes.","volume":"97","author":"Hyka","year":"2001","journal-title":"Blood"},{"key":"R25-7-20210128","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1161\/01.CIR.0000030182.35880.3E","article-title":"Influenza infection promotes macrophage traffic into arteries of mice that is prevented by D-4F, an apolipoprotein A-I mimetic peptide.","volume":"106","author":"Van Lenten","year":"2002","journal-title":"Circulation"},{"key":"R26-7-20210128","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1111\/j.1749-6632.2002.tb04248.x","article-title":"Cytokines, acute-phase proteins, and hormones: IL-1 and TNF-alpha production in contact-mediated activation of monocytes by T lymphocytes.","volume":"966","author":"Burger","year":"2002","journal-title":"Ann N Y Acad Sci"},{"key":"R27-7-20210128","doi-asserted-by":"crossref","first-page":"2847","DOI":"10.1167\/iovs.05-1281","article-title":"Apical corneal barrier disruption in experimental murine dry eye is abrogated by methylprednisolone and doxycycline.","volume":"47","author":"De Paiva","year":"2006","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R28-7-20210128","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1600-0668.2005.00358.x","article-title":"Self-reported eye symptoms and related diagnostic findings\u2014Comparison of risk factor profiles.","volume":"15","author":"Brasche","year":"2005","journal-title":"Indoor Air"},{"key":"R29-7-20210128","doi-asserted-by":"crossref","first-page":"12040","DOI":"10.1073\/pnas.90.24.12040","article-title":"In vivo protection against endotoxin by plasma high density lipoprotein.","volume":"90","author":"Levine","year":"1993","journal-title":"Proc Natl Acad Sci USA"},{"key":"R30-7-20210128","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1161\/01.RES.0000176530.66400.48","article-title":"Inhibition of lipopolysaccharide-induced inflammatory responses by an apolipoprotein AI mimetic peptide.","volume":"97","author":"Gupta","year":"2005","journal-title":"Circ Res"},{"key":"R31-7-20210128","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1093\/abbs\/36.6.419","article-title":"Role of apolipoprotein A-I in protecting against endotoxin toxicity.","volume":"36","author":"Ma","year":"2004","journal-title":"Acta Biochim Biophys Sin (Shanghai)"},{"key":"R32-7-20210128","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1007\/BF00926868","article-title":"Antimicrobial activity of lipoprotein particles containing apolipoprotein Al.","volume":"119","author":"Tada","year":"1993","journal-title":"Mol Cell Biochem"},{"key":"R33-7-20210128","doi-asserted-by":"crossref","first-page":"842","DOI":"10.1136\/bjo.85.7.842","article-title":"Bacterial keratitis: A prospective clinical and microbiological study.","volume":"85","author":"Schaefer","year":"2001","journal-title":"Br J Ophthalmol"},{"key":"R34-7-20210128","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/0042-6822(90)90229-K","article-title":"Antiviral effects of apolipoprotein A-I and its synthetic amphipathic peptide analogs.","volume":"176","author":"Srinivas","year":"1990","journal-title":"Virology"},{"key":"R35-7-20210128","first-page":"537","article-title":"Effectiveness of long-term treatment with pantethine in patients with dyslipidemia.","volume":"8","author":"Arsenio","year":"1986","journal-title":"Clin Ther"},{"key":"R36-7-20210128","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1093\/ajcn\/41.3.578","article-title":"Effects of supplemental pantothenic acid on wound healing: Experimental study in rabbit.","volume":"41","author":"Aprahamian","year":"1985","journal-title":"Am J Clin Nutr"},{"key":"R37-7-20210128","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1024\/0300-9831.69.2.113","article-title":"Studies on wound healing: Effects of calcium d-pantothenate on the migration, proliferation and protein synthesis of human dermal fibroblasts in culture.","volume":"69","author":"Weimann","year":"1999","journal-title":"Int J Vitam Nutr Res"},{"key":"R38-7-20210128","doi-asserted-by":"crossref","first-page":"427","DOI":"10.2165\/00128071-200203060-00005","article-title":"Topical use of dexpanthenol in skin disorders.","volume":"3","author":"Ebner","year":"2002","journal-title":"Am J Clin Dermatol"},{"key":"R39-7-20210128","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1097\/00003226-199907000-00002","article-title":"Corneal thickness is reduced in dry eye.","volume":"18","author":"Liu","year":"1999","journal-title":"Cornea"}],"container-title":["Eye & Contact Lens: Science & Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.lww.com\/00140068-200809000-00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,13]],"date-time":"2021-04-13T01:35:06Z","timestamp":1618277706000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00140068-200809000-00007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9]]},"references-count":39,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1097\/icl.0b013e318184bdb6","relation":{},"ISSN":["1542-2321"],"issn-type":[{"value":"1542-2321","type":"print"}],"subject":[],"published":{"date-parts":[[2008,9]]}}}