{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,28]],"date-time":"2026-07-28T07:12:34Z","timestamp":1785222754983,"version":"3.55.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2012,9]]},"DOI":"10.1097\/ico.0b013e31823f8b40","type":"journal-article","created":{"date-parts":[[2012,6,7]],"date-time":"2012-06-07T10:11:12Z","timestamp":1339063872000},"page":"1028-1035","source":"Crossref","is-referenced-by-count":33,"title":["Activated Macrophages Induce Neovascularization Through Upregulation of MMP-9 and VEGF in Rat Corneas"],"prefix":"10.1097","volume":"31","author":[{"given":"Zhan-rong","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-ping","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miao-li","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-ru","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Xin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Yao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-11-20210204","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.exer.2005.05.001","article-title":". Involvement of IL-6 in the paracrine production of VEGF in ocular HSV-1 infection.","volume":"82","author":"Biswas","year":"2006","journal-title":"Exp Eye Res"},{"key":"R2-11-20210204","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1080\/02713680802245772","article-title":". Inhibitory effect of oral doxycycline on neovascularization in a rat corneal alkali burn model of angiogenesis.","volume":"33","author":"Dan","year":"2008","journal-title":"Curr Eye Res"},{"key":"R3-11-20210204","doi-asserted-by":"crossref","first-page":"2411","DOI":"10.1167\/iovs.09-3745","article-title":". Effects of topical and subconjunctival bevacizumab in high-risk corneal transplant survival.","volume":"51","author":"Dastjerdi","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R4-11-20210204","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1373\/49.1.32","article-title":". Angiogenesis assays: a critical overview.","volume":"49","author":"Auerbach","year":"2003","journal-title":"Clin Chem"},{"key":"R5-11-20210204","doi-asserted-by":"crossref","first-page":"221","DOI":"10.2174\/187221309789257450","article-title":". Corneal neovascularization: molecular events and therapeutic options.","volume":"3","author":"Shakiba","year":"2009","journal-title":"Recent Pat Inflamm Allergy Drug Discov"},{"key":"R6-11-20210204","doi-asserted-by":"crossref","first-page":"365","DOI":"10.2174\/138161209787315783","article-title":"Regulation of angiogenesis by macrophages, dendritic cells, and circulating myelomonocytic cells.","volume":"15","author":"David Dong","year":"2009","journal-title":"Curr Pharm Des"},{"key":"R7-11-20210204","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1097\/ICO.0b013e3181930bcd","article-title":". Opposite roles of CCR2 and CX3CR1 macrophages in alkali-induced corneal neovascularization.","volume":"28","author":"Lu","year":"2009","journal-title":"Cornea"},{"key":"R8-11-20210204","first-page":"3505","article-title":". Prevention of corneal allograft rejection in rats treated with subconjunctival injections of liposomes containing dichloromethylene diphosphonate.","volume":"35","author":"Van der Veen","year":"1994","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R9-11-20210204","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1076\/0271-3683(200001)2011-HFT045","article-title":". Macrophage-depletion influences the course of murine HSV-1 keratitis.","volume":"20","author":"Bauer","year":"2000","journal-title":"Curr Eye Res"},{"key":"R10-11-20210204","doi-asserted-by":"crossref","first-page":"3545","DOI":"10.1167\/iovs.06-0695","article-title":". Role of macrophage migration inhibitory factor in corneal neovascularization.","volume":"48","author":"Usui","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R11-11-20210204","first-page":"87","article-title":"Comparison of the neovascular effects of stimulated macrophages and neutrophils in autologous rabbit corneas.","volume":"120","author":"Moore","year":"1985","journal-title":"Am J Pathol"},{"key":"R12-11-20210204","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1291\/hypres.29.269","article-title":". Transforming growth factor-beta signaling enhances transdifferentiation of macrophages into smooth muscle-like cells.","volume":"29","author":"Ninomiya","year":"2006","journal-title":"Hypertens Res"},{"key":"R13-11-20210204","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1136\/bjo.2007.134346","article-title":"AM, Struyf S, Van Damme J, et al.. Circulating fibrocytes contribute to the myofibroblast population in proliferative vitreoretinopathy epiretinal membranes.","volume":"92","year":"2008","journal-title":"Br J Ophthalmol"},{"key":"R14-11-20210204","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1089\/152581602760404630","article-title":"HIV-1 gp120 modulates the immunological function and expression of accessory and co-stimulatory molecules of monocyte-derived dendritic cells.","volume":"11","author":"Williams","year":"2002","journal-title":"J Hematother Stem Cell Res"},{"key":"R15-11-20210204","first-page":"2590","article-title":". The novel tubulin-binding drug BTO-956 inhibits R3230AC mammary carcinoma growth and angiogenesis in Fischer 344 rats.","volume":"7","author":"Shan","year":"2001","journal-title":"Clin Cancer Res"},{"key":"R16-11-20210204","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1111\/j.1349-7006.2008.00853.x","article-title":"Molecular links between tumor angiogenesis and inflammation: inflammatory stimuli of macrophages and cancer cells as targets for therapeutic strategy.","volume":"99","author":"Ono","year":"2008","journal-title":"Cancer Sci"},{"key":"R17-11-20210204","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/0163-7258(91)90077-Y","article-title":". Macrophage-derived angiogenesis factors.","volume":"51","author":"Sunderkotter","year":"1991","journal-title":"Pharmacol Ther"},{"key":"R18-11-20210204","doi-asserted-by":"crossref","first-page":"1016","DOI":"10.1038\/jid.2008.310","article-title":". Tumor-associated macrophage-induced invasion and angiogenesis of human basal cell carcinoma cells by cyclooxygenase-2 induction.","volume":"129","author":"Tjiu","year":"2009","journal-title":"J Invest Dermatol"},{"key":"R19-11-20210204","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1002\/jlb.55.3.410","article-title":". Macrophages and angiogenesis.","volume":"55","author":"Sunderkotter","year":"1994","journal-title":"J Leukoc Biol"},{"key":"R20-11-20210204","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1091\/mbc.3.2.211","article-title":". Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors.","volume":"3","author":"Berse","year":"1992","journal-title":"Mol Biol Cell"},{"key":"R21-11-20210204","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.cca.2006.06.033","article-title":"Growth hormone, VEGF and FGF: involvement in rheumatoid arthritis.","volume":"375","author":"Malemud","year":"2007","journal-title":"Clin Chim Acta"},{"key":"R22-11-20210204","doi-asserted-by":"crossref","first-page":"1915","DOI":"10.1038\/sj.gt.3301320","article-title":". Blockade of TGF-beta by in vivo gene transfer of a soluble TGF-beta type II receptor in the muscle inhibits corneal opacification, edema and angiogenesis.","volume":"7","author":"Sakamoto","year":"2000","journal-title":"Gene Ther"},{"key":"R23-11-20210204","first-page":"3937","article-title":"Expression of MMP-2, MMP-7, MMP-9, MMP-10 and MMP-11 in human astrocytic and oligodendroglial gliomas.","volume":"23","author":"Thorns","year":"2003","journal-title":"Anticancer Res"},{"key":"R24-11-20210204","doi-asserted-by":"crossref","first-page":"34","DOI":"10.2174\/138920108783497631","article-title":". Matrix metalloproteinase-9gelatinase B is a putative therapeutic target of chronic obstructive pulmonary disease and multiple sclerosis.","volume":"9","author":"Muroski","year":"2008","journal-title":"Curr Pharm Biotechnol"},{"key":"R25-11-20210204","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1038\/labinvest.2008.91","article-title":". Activation of hepatic stellate cells is associated with cytokine expression in thioacetamide-induced hepatic fibrosis in mice.","volume":"88","author":"Salguero Palacios","year":"2008","journal-title":"Lab Invest"},{"key":"R26-11-20210204","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/S0161-6420(00)00590-X","article-title":". The role of matrix metalloproteinases in ulcerative keratolysis associated with perioperative diclofenac use.","volume":"108","author":"OBrien","year":"2001","journal-title":"Ophthalmology"},{"key":"R27-11-20210204","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1002\/path.1198","article-title":". Metalloelastase (MMP-12) expression by tumour cells in squamous cell carcinoma of the vulva correlates with invasiveness, while that by macrophages predicts better outcome.","volume":"198","author":"Kerkela","year":"2002","journal-title":"J Pathol"},{"key":"R28-11-20210204","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1016\/j.orthres.2003.11.008","article-title":". Sequential dynamics of inflammatory cytokine, angiogenesis inducing factor and matrix degrading enzymes during spontaneous resorption of the herniated disc.","volume":"22","author":"Kato","year":"2004","journal-title":"J Orthop Res"},{"key":"R29-11-20210204","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1006\/jsre.2002.6532","article-title":"Role of cyclooxygenase-2 in breast cancer.","volume":"108","author":"Singh","year":"2002","journal-title":"J Surg Res"},{"key":"R30-11-20210204","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/BOR.0b013e32805e87ae","article-title":"Macrophages and their products in rheumatoid arthritis.","volume":"19","author":"Szekanecz","year":"2007","journal-title":"Curr Opin Rheumatol"}],"container-title":["Cornea"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/ICO.0b013e31823f8b40","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,24]],"date-time":"2021-05-24T19:33:38Z","timestamp":1621884818000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00003226-201209000-00011"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,9]]},"references-count":30,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2012]]}},"URL":"https:\/\/doi.org\/10.1097\/ico.0b013e31823f8b40","relation":{},"ISSN":["0277-3740"],"issn-type":[{"value":"0277-3740","type":"print"}],"subject":[],"published":{"date-parts":[[2012,9]]}}}