{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,5]],"date-time":"2025-04-05T05:27:54Z","timestamp":1743830874794},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,5]]},"DOI":"10.1097\/ico.0b013e318274a690","type":"journal-article","created":{"date-parts":[[2013,2,13]],"date-time":"2013-02-13T09:43:59Z","timestamp":1360748639000},"page":"658-666","source":"Crossref","is-referenced-by-count":9,"title":["Azithromycin Treatment Increases Survival of High-Risk Corneal Allotransplants"],"prefix":"10.1097","volume":"32","author":[{"given":"Carlos A.","family":"Medina","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander M.","family":"Rowe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongmin","family":"Yun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jared E.","family":"Knickelbein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kira L.","family":"Lathrop","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert L.","family":"Hendricks","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-31-20210204","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1111\/j.1442-9071.2005.01134.x","article-title":"Centennial review of corneal transplantation.","volume":"33","author":"Moffatt","year":"2005","journal-title":"Clin Experiment Ophthalmol"},{"key":"R2-31-20210204","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1001\/archopht.1993.01090060087029","article-title":". Five-year corneal graft survival. A large, single-center patient cohort.","volume":"111","author":"Price","year":"1993","journal-title":"Arch Ophthalmol"},{"key":"R4-31-20210204","doi-asserted-by":"crossref","first-page":"1392","DOI":"10.1001\/archopht.1992.01080220054021","article-title":"Effectiveness of histocompatibility matching in high-risk corneal transplantation. The Collaborative Corneal Transplantation Studies Research Group.","volume":"110","year":"1992","journal-title":"Arch Ophthalmol"},{"key":"R5-31-20210204","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1001\/archopht.126.1.71","article-title":". Promotion of graft survival by vascular endothelial growth factor a neutralization after high-risk corneal transplantation.","volume":"126","author":"Bachmann","year":"2008","journal-title":"Arch Ophthalmol"},{"key":"R6-31-20210204","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1097\/TP.0b013e3181636d9d","article-title":". Effect of CXCL-1KC production in high risk vascularized corneal allografts on T cell recruitment and graft rejection.","volume":"85","author":"Amescua","year":"2008","journal-title":"Transplantation"},{"key":"R7-31-20210204","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1080\/08820530500509358","article-title":"Angiogenesis and lymphangiogenesis-implications for corneal immunity.","volume":"21","author":"Dana","year":"2006","journal-title":"Semin Ophthalmol"},{"key":"R8-31-20210204","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1038\/nm1078","article-title":". Vascular endothelial growth factor receptor-3 mediates induction of corneal alloimmunity.","volume":"10","author":"Chen","year":"2004","journal-title":"Nat Med"},{"key":"R9-31-20210204","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1097\/00003226-200304000-00021","article-title":". Corneal lymphangiogenesis: evidence, mechanisms, and implications for corneal transplant immunology.","volume":"22","author":"Cursiefen","year":"2003","journal-title":"Cornea"},{"key":"R10-31-20210204","first-page":"2485","article-title":"Loss and restoration of immune privilege in eyes with corneal neovascularization.","volume":"37","author":"Dana","year":"1996","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R11-31-20210204","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1097\/ACI.0b013e32833dfa11","article-title":"High-risk corneal allografts and why they lose their immune privilege.","volume":"10","author":"Niederkorn","year":"2010","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"R12-31-20210204","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.4049\/jimmunol.167.4.1891","article-title":". Role of CD4 and CD8 T cells in allorecognition: lessons from corneal transplantation.","volume":"167","author":"Boisgerault","year":"2001","journal-title":"J Immunol"},{"key":"R13-31-20210204","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1097\/00007890-199906270-00001","article-title":"The immune privilege of corneal allografts.","volume":"67","author":"Niederkorn","year":"1999","journal-title":"Transplantation"},{"key":"R14-31-20210204","first-page":"1130","article-title":"Murine orthotopic corneal transplantation in high-risk eyes. Rejection is dictated primarily by weak rather than strong alloantigens.","volume":"38","author":"Sano","year":"1997","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R15-31-20210204","doi-asserted-by":"crossref","first-page":"1302","DOI":"10.1097\/00007890-200011150-00007","article-title":"Analysis of primed donor-specific T cells in recipient mice bearing orthotopic corneal allografts.","volume":"70","author":"Sano","year":"2000","journal-title":"Transplantation"},{"key":"R16-31-20210204","first-page":"427","article-title":". Characterization of cell-mediated immune responses elicited by orthotopic corneal allografts in mice.","volume":"36","author":"Sonoda","year":"1995","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R17-31-20210204","first-page":"2614","article-title":"Role of CD4 T cells in immunobiology of orthotopic corneal transplants in mice.","volume":"40","author":"Yamada","year":"1999","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"suppl B","key":"R18-31-20210204","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/jac\/41.suppl_2.47","article-title":"Comparative anti-inflammatory effects of roxithromycin, azithromycin and clarithromycin.","volume":"41","author":"Scaglione","year":"1998","journal-title":"J Antimicrob Chemother"},{"key":"R19-31-20210204","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/j.1365-2249.2007.03299.x","article-title":". Differing effects of clarithromycin and azithromycin on cytokine production by murine dendritic cells.","volume":"147","author":"Sugiyama","year":"2007","journal-title":"Clin Exp Immunol"},{"key":"R20-31-20210204","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1093\/jac\/dkn007","article-title":". Azithromycin alters macrophage phenotype.","volume":"61","author":"Murphy","year":"2008","journal-title":"J Antimicrob Chemother"},{"key":"R21-31-20210204","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1006\/mthe.2001.0492","article-title":". Viral IL-10 gene transfer inhibits DTH responses to soluble antigens: evidence for involvement of genetically modified dendritic cells and macrophages.","volume":"4","author":"Whalen","year":"2001","journal-title":"Mol Ther"},{"key":"R22-31-20210204","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1182\/blood.V93.1.208","article-title":"Mechanism of interleukin-10 inhibition of T-helper cell activation by superantigen at the level of the cell cycle.","volume":"93","author":"Perrin","year":"1999","journal-title":"Blood"},{"key":"R23-31-20210204","doi-asserted-by":"crossref","first-page":"2713","DOI":"10.4049\/jimmunol.147.8.2713","article-title":". Production of IL-10 by CD4 T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection.","volume":"147","author":"Sher","year":"1991","journal-title":"J Immunol"},{"key":"R24-31-20210204","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1167\/iovs.10-5658","article-title":". Effect of topical azithromycin on corneal innate immune responses.","volume":"52","author":"Sadrai","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"R25-31-20210204","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.1164\/rccm.200402-200OC","article-title":". Azithromycin blocks neutrophil recruitment in Pseudomonas endobronchial infection.","volume":"170","author":"Tsai","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"R26-31-20210204","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.ejphar.2006.03.074","article-title":". Anti-inflammatory activity of azithromycin attenuates the effects of lipopolysaccharide administration in mice.","volume":"539","author":"Ivetic Tkalcevic","year":"2006","journal-title":"Eur J Pharmacol"},{"key":"R27-31-20210204","first-page":"156","article-title":". Anti-inflammatory activity of macrolide antibiotics.","volume":"292","author":"Ianaro","year":"2000","journal-title":"J Pharmacol Exp Ther"},{"key":"R28-31-20210204","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1159\/000196450","article-title":". Effect of roxithromycin on peripheral neutrophil adhesion molecules in patients with chronic lower respiratory tract disease.","volume":"62","author":"Kusano","year":"1995","journal-title":"Respiration"},{"key":"R29-31-20210204","first-page":"397","article-title":". Cytokine-induced neutrophil-derived interleukin-8.","volume":"141","author":"Strieter","year":"1992","journal-title":"Am J Pathol"},{"key":"R30-31-20210204","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1124\/jpet.109.155838","article-title":". Azithromycin and clarithromycin inhibit lipopolysaccharide-induced murine pulmonary neutrophilia mainly through effects on macrophage-derived granulocyte-macrophage colony-stimulating factor and interleukin-1beta.","volume":"331","author":"Bosnar","year":"2009","journal-title":"J Pharmacol Exp Ther"},{"key":"R31-31-20210204","doi-asserted-by":"crossref","first-page":"148","DOI":"10.4049\/jimmunol.182.1.148","article-title":". Levels of Foxp3 in regulatory T cells reflect their functional status in transplantation.","volume":"182","author":"Chauhan","year":"2009","journal-title":"J Immunol"},{"key":"R32-31-20210204","doi-asserted-by":"crossref","first-page":"3067","DOI":"10.2174\/1381612043383403","article-title":"Cellular and molecular effects of macrolides on leukocyte function.","volume":"10","author":"Labro","year":"2004","journal-title":"Curr Pharm Des"},{"issue":"suppl 9A","key":"R34-31-20210204","first-page":"5S","article-title":"Clinical implications of the immunomodulatory effects of macrolides.","volume":"117","author":"Tamaoki","year":"2004","journal-title":"Am J Med"},{"key":"R35-31-20210204","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1164\/ajrccm.156.1.9612065","article-title":". Erythromycin modulates IL-8 expression in normal and inflamed human bronchial epithelial cells.","volume":"156","author":"Takizawa","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"R36-31-20210204","doi-asserted-by":"crossref","first-page":"781","DOI":"10.1006\/bbrc.1995.1727","article-title":". Erythromycin suppresses interleukin 6 expression by human bronchial epithelial cells: a potential mechanism of its anti-inflammatory action.","volume":"210","author":"Takizawa","year":"1995","journal-title":"Biochem Biophys Res Commun"},{"key":"R37-31-20210204","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1002\/jlb.56.5.559","article-title":". Essential involvement of interleukin-8 (IL-8) in acute inflammation.","volume":"56","author":"Harada","year":"1994","journal-title":"J Leukoc Biol"},{"key":"R38-31-20210204","doi-asserted-by":"crossref","first-page":"L75","DOI":"10.1152\/ajplung.00093.2005","article-title":"Macrolide antibiotics modulate ERK phosphorylation and IL-8 and GM-CSF production by human bronchial epithelial cells.","volume":"290","author":"Shinkai","year":"2006","journal-title":"Am J Physiol Lung Cell Mol Physiol"}],"container-title":["Cornea"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/ICO.0b013e318274a690","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,29]],"date-time":"2023-06-29T12:06:43Z","timestamp":1688040403000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00003226-201305000-00031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,5]]},"references-count":36,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1097\/ico.0b013e318274a690","relation":{},"ISSN":["0277-3740"],"issn-type":[{"value":"0277-3740","type":"print"}],"subject":[],"published":{"date-parts":[[2013,5]]}}}