{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T16:02:45Z","timestamp":1777737765430,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Innovations\ufffd(Phila)"],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Minimally invasive surgical pulmonary vein isolation (SMI-PVI) is an emerging therapy for the treatment of symptomatic drug-refractory atrial fibrillation (AF). Nevertheless, the midterm and long-term results of SMI-PVI remain unknown. The aim of this retrospective multicenter study was to report on midterm efficacy and safety of SMI-PVI.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study design was retrospective, multicentric, and observational. From July 2005 to November 2011, a total of 86 patients with drug-refractory paroxysmal or persistent AF underwent SMI-PVI in three centers. Patients were eligible for SMI-PVI if they had symptomatic, drug-refractory AF or after failed transcatheter pulmonary vein isolation. Success was defined as absence of AF on 24- or 96-hour Holter monitoring during follow-up, in the absence of antiarrhythmic drugs (AADs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The mean \u00b1 SD age was 54 \u00b1 11 years, and 78% were men. The median AF duration was 30 months (range, 2\u2013203); paroxysmal AF was present in 86% of the patients, persistent in 14%. Fifteen patients (17%) underwent previous transcatheter ablations. After a median follow-up of 24 months (range, 6\u201378), 72% of all patients were free from atrial arrhythmias without the use of AADs. With AADs, this was 83%. Major perioperative adverse events occurred in 7 patients (8%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>This retrospective multicenter study shows that SMI-PVI is effective at a median follow-up of 24 months for the treatment of mostly paroxysmal drug-refractory AF. Perioperative adverse events do remain a point of caution.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/imi.0000000000000029","type":"journal-article","created":{"date-parts":[[2013,12,19]],"date-time":"2013-12-19T07:05:46Z","timestamp":1387436746000},"page":"410-415","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Surgical Minimally Invasive Pulmonary Vein Isolation for Lone Atrial Fibrillation"],"prefix":"10.1177","volume":"8","author":[{"given":"Gijs E.","family":"De Maat","sequence":"first","affiliation":[{"name":"Department of Cardio-Thoracic Surgery University Medical Center Groningen, Groningen, The Netherlands"},{"name":"Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alberto","family":"Pozzoli","sequence":"additional","affiliation":[{"name":"Department of Cardio-Thoracic Surgery University Medical Center Groningen, Groningen, The Netherlands"},{"name":"Cardiac Surgery Unit, San Raffaele Scientific Institute, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcoen F.","family":"Scholten","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Medisch Spectrum Twente, Enschede, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans L.","family":"Hillege","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabelle C.","family":"Van Gelder","sequence":"additional","affiliation":[{"name":"Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ottavio R.","family":"Alfieri","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit, San Raffaele Scientific Institute, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefano","family":"Benussi","sequence":"additional","affiliation":[{"name":"Cardiac Surgery Unit, San Raffaele Scientific Institute, Milan, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo A.","family":"Mariani","sequence":"additional","affiliation":[{"name":"Department of Cardio-Thoracic Surgery University Medical Center Groningen, Groningen, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,11,1]]},"reference":[{"key":"bibr1-imi.0000000000000029","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.595140"},{"key":"bibr2-imi.0000000000000029","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2009.2029"},{"key":"bibr3-imi.0000000000000029","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1996.00440210109011"},{"key":"bibr4-imi.0000000000000029","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/euq350"},{"key":"bibr5-imi.0000000000000029","doi-asserted-by":"publisher","DOI":"10.1093\/europace\/eus027"},{"key":"bibr6-imi.0000000000000029","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2010.05.061"},{"key":"bibr7-imi.0000000000000029","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2005.03.041"},{"key":"bibr8-imi.0000000000000029","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2009.11.065"},{"key":"bibr9-imi.0000000000000029","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCEP.109.854828"},{"key":"bibr10-imi.0000000000000029","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.074047"},{"key":"bibr11-imi.0000000000000029","doi-asserted-by":"publisher","DOI":"10.1007\/s10840-011-9650-5"},{"key":"bibr12-imi.0000000000000029","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2006.09.022"},{"key":"bibr13-imi.0000000000000029","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1016\/j.jacc.2006.07.009","volume":"48","author":"Fuster 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Technology and Techniques in Cardiothoracic and Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1097\/imi.0000000000000029","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1097\/imi.0000000000000029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T11:20:23Z","timestamp":1777461623000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1097\/imi.0000000000000029"}},"subtitle":["Midterm Results of a Multicenter 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