{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T15:57:08Z","timestamp":1777737428996,"version":"3.51.4"},"reference-count":38,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2011,1,1]],"date-time":"2011-01-01T00:00:00Z","timestamp":1293840000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Innovations\ufffd(Phila)"],"published-print":{"date-parts":[[2011,1]]},"abstract":"<jats:p>Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a minimally invasive modality for mediastinal lymph node staging in lung cancer patients as well as for the diagnosis of mediastinal and hilar adenopathy. The high diagnostic yield of EBUS-TBNA for lymph node staging has been shown in systematic reviews and meta-analysis. It has attracted physicians and surgeons as an alternative modality to surgical biopsy for the assessment of patients with enlarged mediastinal and\/or hilar lymph nodes. Cell blocks obtained by EBUS-TBNA can be applicable not only for pathologic diagnosis but also for further investigations such as immunohistochemistry and fluorescence in situ hybridization. In addition, samples obtained by EBUS-TBNA can also be used for molecular analysis. Unlike regular bronchoscopy, EBUS-TBNA uses the convex probe EBUS with an ultrasound probe on the tip of a flexible bronchoscope. It is important for the bronchoscopist to fully understand the mediastinal anatomy and be able to correlate it with the ultrasound images for a successful EBUS-TBNA. The dedicated transbronchial needle used for EBUS-TBNA is somewhat different from an ordinary transbronchial biopsy forceps. Training is mandatory for achieving high diagnostic yield without complications. The learning curve of EBUS-TBNA is different from each physician, and continuous training program will be needed for impartiality. This article explains the detailed techniques of EBUS-TBNA to master this innovative procedure.<\/jats:p>","DOI":"10.1097\/imi.0b013e31820c91a7","type":"journal-article","created":{"date-parts":[[2011,2,16]],"date-time":"2011-02-16T05:46:15Z","timestamp":1297835175000},"page":"57-64","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["The Techniques of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration"],"prefix":"10.1177","volume":"6","author":[{"given":"Takahiro","family":"Nakajima","sequence":"first","affiliation":[{"name":"Division of Thoracic Surgery, Toronto General Hospital, University Health Network, Toronto, ON Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuhiro","family":"Yasufuku","sequence":"additional","affiliation":[{"name":"Division of Thoracic Surgery, Toronto General Hospital, University Health Network, Toronto, ON Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2011,1,1]]},"reference":[{"key":"bibr1-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-1362"},{"key":"bibr2-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1097\/CPM.0b013e3181ef721c"},{"key":"bibr3-imi.0b013e31820c91a7","first-page":"293","volume":"11","author":"Yasufuku K.","year":"2004","journal-title":"Oncol Rep."},{"key":"bibr4-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.126.1.122"},{"key":"bibr5-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2005.07.013"},{"key":"bibr6-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.130.3.710"},{"key":"bibr7-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2008.11.043"},{"key":"bibr8-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2008.109868"},{"key":"bibr9-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00097908"},{"key":"bibr10-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1053\/j.jvca.2007.09.017"},{"key":"bibr11-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3181a0d82e"},{"key":"bibr12-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.09-2006"},{"key":"bibr13-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2009.06.015"},{"key":"bibr14-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-2105"},{"key":"bibr15-imi.0b013e31820c91a7","volume-title":"Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Manual EBUS-TBNA at a Glance","author":"Yasufuku K.","year":"2009"},{"key":"bibr16-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.05.00095404"},{"key":"bibr17-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2005.047829"},{"key":"bibr18-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.06.00124905"},{"key":"bibr19-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.09.002"},{"key":"bibr20-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1186\/1749-8090-5-33"},{"key":"bibr21-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00025708"},{"key":"bibr22-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2008.01.005"},{"key":"bibr23-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2009.127274"},{"key":"bibr24-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1097\/LBR.0b013e3181e70007"},{"key":"bibr25-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2007.14.9229"},{"key":"bibr26-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.49.3154"},{"key":"bibr27-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e31818396b9"},{"key":"bibr28-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3181d35627"},{"key":"bibr29-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtcvs.2007.07.022"},{"key":"bibr30-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2007.084079"},{"key":"bibr31-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e3181d873be"},{"key":"bibr32-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00028706"},{"key":"bibr33-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2009.07.013"},{"key":"bibr34-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.07-0095"},{"key":"bibr35-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00028109"},{"key":"bibr36-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2007.090324"},{"key":"bibr37-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(09)70364-X"},{"key":"bibr38-imi.0b013e31820c91a7","doi-asserted-by":"publisher","DOI":"10.1038\/nature05945"}],"container-title":["Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1097\/imi.0b013e31820c91a7","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1097\/imi.0b013e31820c91a7","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T11:19:32Z","timestamp":1777461572000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1097\/imi.0b013e31820c91a7"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":38,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011,1]]}},"alternative-id":["10.1097\/imi.0b013e31820c91a7"],"URL":"https:\/\/doi.org\/10.1097\/imi.0b013e31820c91a7","relation":{},"ISSN":["1556-9845","1559-0879"],"issn-type":[{"value":"1556-9845","type":"print"},{"value":"1559-0879","type":"electronic"}],"subject":[],"published":{"date-parts":[[2011,1]]}}}