{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T15:59:48Z","timestamp":1777737588982,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Innovations\ufffd(Phila)"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Granted that minimally invasive mitral valve (MV) surgery short-term results were found to be equivalent to those achieved with traditional sternotomy with respect to perioperative morbidity and echocardiographic outcomes, little is known about the long-term efficacy of this approach. This report analyzes a 10-year single-surgeon experience with minimally invasive MV surgery through a right minithoracotomy with peripheral cannulation and external aortic cross-clamping and MV repair (MVR) by direct vision.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We studied 179 patients (48% female) who underwent MVR between December 1999 and December 2010. Mean age was 40.2 \u00b1 10.1 years (range, 15\u201367 years). One hundred seventy patients (95.0%) had degenerative diseases, and nine patients (5.0%) had endocarditic diseases. Repair techniques for degenerative disease with posterior leaflet prolapse (74 patients, 43.5%) consisted of quadrangular resection (QR) and annuloplasty (AP) combined with sliding plasty (49 patients, 58.1%); for anterior leaflet prolapse (28 patients, 16.5%) and bileaflet prolapse (66 patients, 38.8%), edge-to-edge repair (EE) and AP; in 2 patients (1.2%), annular dilatation alone consisting of AP. Repair techniques for endocarditic disease consisted of EE in six patients (66.7%), perforation closure in two patients (22.2%), and QR combined with AP in one patient (11.1%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>All patients survived the operation and were discharged with MV regurgitation (MR) less than 2+\/4+. At 10 years\u2019 follow-up, overall survival was 98.7% \u00b1 1.2%, freedom from redo was 98.5% \u00b1 1.1%, freedom from MR recurrence (&gt;2+\/4+) in QR and in EE repair were, respectively, 91.7% \u00b1 2.2% and 90.0% \u00b1 2.4% (P = not significant). The linearized rates of overall mortality, MR recurrence (&gt;2+\/4+), and redo at follow-up are 0.10% \u00b1 0.10% per year, 0.63% \u00b1 0.26% per year, and 0.21% \u00b1 0.15% per year, respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Minimally invasive MVR can be performed with very good perioperative and long-term results. Freedom from MR greater than 2+\/4+ recurrence for patients with QR is equivalent to that with EE repair in our patient cohort.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/imi.0b013e31826f7ac4","type":"journal-article","created":{"date-parts":[[2012,11,2]],"date-time":"2012-11-02T06:46:12Z","timestamp":1351838772000},"page":"270-273","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Ten Years\u2019 Follow-Up of Single-Surgeon Minimally Invasive Reparative Surgery for Degenerative Mitral Valve Disease"],"prefix":"10.1177","volume":"7","author":[{"given":"Alessandro","family":"D'Alfonso","sequence":"first","affiliation":[{"name":"Division of Cardiac Surgery, Presidio Lancisi, Ospedali Riuniti, Ancona, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Filippo","family":"Capestro","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Presidio Lancisi, Ospedali Riuniti, Ancona, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlo","family":"Zingaro","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Presidio Lancisi, Ospedali Riuniti, Ancona, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sacha","family":"Matteucci","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Presidio Lancisi, Ospedali Riuniti, Ancona, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Rescigno","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Presidio Lancisi, Ospedali Riuniti, Ancona, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lucia","family":"Torracca","sequence":"additional","affiliation":[{"name":"Division of Cardiac Surgery, Presidio Lancisi, Ospedali Riuniti, Ancona, Italy."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,7,1]]},"reference":[{"key":"bibr1-imi.0b013e31826f7ac4","unstructured":"MillerG.W. King of Hearts: The True Story of the Maverick Who Pioneered Open Heart Surgery. New York, NY: TimesBooks; 2000, 292 p."},{"key":"bibr2-imi.0b013e31826f7ac4","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2009.05.023"},{"key":"bibr3-imi.0b013e31826f7ac4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2009.03.058"},{"key":"bibr4-imi.0b013e31826f7ac4","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2004.10.032"},{"key":"bibr5-imi.0b013e31826f7ac4","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.96.6.1819"},{"key":"bibr6-imi.0b013e31826f7ac4","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcts.2008.07.057"},{"key":"bibr7-imi.0b013e31826f7ac4","first-page":"709","volume":"14","author":"Ryan W.H.","year":"2005","journal-title":"J Heart Valve Dis."},{"key":"bibr8-imi.0b013e31826f7ac4","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(99)00284-2"},{"key":"bibr9-imi.0b013e31826f7ac4","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(01)02978-2"},{"key":"bibr10-imi.0b013e31826f7ac4","doi-asserted-by":"publisher","DOI":"10.1161\/hc37t1.094903"}],"container-title":["Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1097\/imi.0b013e31826f7ac4","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1097\/imi.0b013e31826f7ac4","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T11:19:54Z","timestamp":1777461594000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1097\/imi.0b013e31826f7ac4"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":10,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["10.1097\/imi.0b013e31826f7ac4"],"URL":"https:\/\/doi.org\/10.1097\/imi.0b013e31826f7ac4","relation":{},"ISSN":["1556-9845","1559-0879"],"issn-type":[{"value":"1556-9845","type":"print"},{"value":"1559-0879","type":"electronic"}],"subject":[],"published":{"date-parts":[[2012,7]]}}}