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Data on 241 children screened for latent tuberculosis infection (LTBI) between January 2011 and July 2018 were analyzed; 12.4% of children screened under the previous guidelines were treated for LTBI, compared to 33.3% under the new ones (<jats:italic toggle=\"yes\">P<\/jats:italic> &lt; 0.001).<\/jats:p>","DOI":"10.1097\/inf.0000000000003786","type":"journal-article","created":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T21:00:39Z","timestamp":1675371639000},"page":"e88-e89","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Optimizing the Threshold to Treat Children for Latent Tuberculosis Infection: A North-East England Experience"],"prefix":"10.1097","volume":"42","author":[{"given":"George James","family":"Porter","sequence":"first","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom"},{"name":"Great North Children\u2019s Hospital, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Whyte","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, James Cook University Hospital, Middlesbrough, United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elisabetta Ghimenton","family":"Walters","sequence":"additional","affiliation":[{"name":"Great North Children\u2019s Hospital, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, United Kingdom"},{"name":"Desmond Tutu TB Centre, Stellenbosch University, Cape Town, South Africa."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen","family":"Owens","sequence":"additional","affiliation":[{"name":"Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom"},{"name":"Great North Children\u2019s Hospital, Newcastle upon Tyne NHS Foundation Trust, Newcastle upon 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