{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T13:04:20Z","timestamp":1792760660332,"version":"4.5.0"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Subperiosteal abscesses (SAs) are a complication of osteomyelitis that requires surgical intervention. This study aimed to characterize the occurrence of subsequent complications in pediatric patients with osteomyelitis and accompanying SA.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Fourteen pediatric patients with SAs were included. We recorded clinical information, including age at diagnosis, interval (days) between the onset of symptoms and diagnosis, location of SAs (long\/flat bone), pathogens [methicillin-resistant <jats:italic toggle=\"yes\">Staphylococcus aureus<\/jats:italic> (MRSA)\/non-MRSA], treatment period (days) and any subsequent complications. Patients were classified based on SAs with or without complications. Mann-Whitney <jats:italic toggle=\"yes\">U<\/jats:italic> and Fisher exact tests were used for statistical analyses, and data are expressed as median and interquartile range.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>Six patients (42.9%) had subsequent complications. There were significant differences in location of SAs between these two groups (long\/flat bone, with versus without complication = 6\/0 versus 3\/5; <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.031). No significant differences were observed between the groups in terms of age [with versus without complication = 13.8 (9.7\u201324.5) versus 556.3 (5.0\u2013107.8) months; <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.491], the interval (days) between symptoms onset and diagnosis [with versus without complications = 5 (1\u201310) versus 5 (3\u20136.5) days; <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.950], pathogenesis (MRSA\/non-MRSA, with versus without complication = 4\/2 versus 2\/6; <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.277) and treatment period [with versus without complication = 50.5 (31\u201357) versus 29 (24.5\u201341.5) days; <jats:italic toggle=\"yes\">P<\/jats:italic> = 0.108].<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>Pediatric patients with SAs in the long bones have a higher likelihood of experiencing subsequent complications than those with SAs in flat bones. Physicians should carefully manage this vulnerable patient group.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/inf.0000000000004435","type":"journal-article","created":{"date-parts":[[2024,6,20]],"date-time":"2024-06-20T15:00:31Z","timestamp":1718895631000},"page":"1027-1032","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Subsequent Complications of Pediatric Patients With Osteomyelitis and Accompanying Subperiosteal Abscess"],"prefix":"10.1097","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9523-4077","authenticated-orcid":false,"given":"Takahiro","family":"Hosokawa","sequence":"first","affiliation":[{"name":"From the Department of Radiology, Saitama Children\u2019s Medical Center, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuntaro","family":"Deguchi","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Immunology, Saitama Children\u2019s Medical Center, Saitama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haruka","family":"Takei","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Immunology, Saitama Children\u2019s Medical Center, Saitama, Japan."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yumiko","family":"Sato","sequence":"additional","affiliation":[{"name":"From the Department of Radiology, Saitama Children\u2019s Medical Center, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Tanami","sequence":"additional","affiliation":[{"name":"From the Department of Radiology, Saitama Children\u2019s Medical Center, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eiji","family":"Oguma","sequence":"additional","affiliation":[{"name":"From the Department of Radiology, Saitama Children\u2019s Medical Center, Saitama, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,6,17]]},"reference":[{"key":"R1-20250614","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1016\/j.jcot.2019.03.022","article-title":"Osteomyelitis of flat bones: a report of 20 cases and review of the literature.","volume":"10","author":"Mboutol-Mandavo","year":"2019","journal-title":"J Clin Orthop Trauma"},{"key":"R2-20250614","doi-asserted-by":"crossref","first-page":"634","DOI":"10.1097\/BPO.0000000000000332","article-title":"Pediatric acute hematogenous osteomyelitis.","volume":"35","author":"Street","year":"2015","journal-title":"J Pediatr Orthop"},{"key":"R3-20250614","doi-asserted-by":"crossref","first-page":"e614","DOI":"10.1097\/BPO.0000000000002443","article-title":"An update on pediatric acute hematogenous osteomyelitis in New Zealand - a decade on.","volume":"43","author":"McDonald","year":"2023","journal-title":"J Pediatr Orthop"},{"key":"R4-20250614","doi-asserted-by":"crossref","first-page":"399","DOI":"10.2214\/ajr.165.2.7618566","article-title":"Osteomyelitis and septic arthritis in children: appropriate use of imaging to guide treatment.","volume":"165","author":"Jaramillo","year":"1995","journal-title":"AJR Am J Roentgenol"},{"issue":"8s","key":"R5-20250614","doi-asserted-by":"crossref","first-page":"104789","DOI":"10.1016\/j.idnow.2023.104789","article-title":"Antibiotic therapy for osteoarticular infections in 2023: Proposals from the Pediatric Infectious Pathology Group (GPIP).","volume":"53","author":"Lorrot","year":"2023","journal-title":"Infect Dis Now"},{"key":"R6-20250614","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.21037\/qims-23-1138","article-title":"State of the art in the diagnostic evaluation of osteomyelitis: exploring the role of advanced MRI sequences-a narrative review.","volume":"14","author":"Perera Molligoda Arachchige","year":"2024","journal-title":"Quant Imaging Med Surg"},{"key":"R7-20250614","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1007\/BF02012120","article-title":"Early detection of subperiosteal abscesses by ultrasonography. 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