{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,15]],"date-time":"2025-06-15T04:05:47Z","timestamp":1749960347182,"version":"3.41.0"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Cat-scratch disease is a common zoonosis in children. However, atypical clinical presentation of cat-scratch disease is less common, and lung involvement is particularly rare. The usual presentation of lung disease in bartonellosis includes other organ involvement and is more common in immunocompromised patients.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Case Report:<\/jats:title>\n            <jats:p>We present a 10-year-old immunocompetent patient with pneumonia and inoculated empyema caused by <jats:italic toggle=\"yes\">Bartonella henselae<\/jats:italic>, without any other organ involvement, which occurred 2 weeks after lymphadenopathy. The definite diagnosis was established using the polymerase chain reaction of the empyema obtained from thoracocentesis. The boy was treated with several antibiotics (ceftriaxone, azithromycin, amoxicillin with clavulanic acid, meropenem and vancomycin) and completely recovered after the 3-month follow-up period.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusions:<\/jats:title>\n            <jats:p>This is a unique case of the difficult-to-treat pneumonia with inoculated empyema, caused by <jats:italic toggle=\"yes\">B. henselae<\/jats:italic>, in an immunocompetent child, without any other organ involvement. The clinical course was favorable. A high level of clinical suspicion is mandatory for the diagnosis.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/inf.0000000000004499","type":"journal-article","created":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T14:34:34Z","timestamp":1722436474000},"page":"e451-e453","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Pneumonia With Empyema: A Rare Clinical Presentation of Bartonella henselae Infection in a 10-Year-old Boy"],"prefix":"10.1097","volume":"43","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1252-9609","authenticated-orcid":false,"given":"Iva","family":"Topalu\u0161i\u0107","sequence":"first","affiliation":[{"name":"Department of Pulmonology, Allergology, Immunology and Rheumatology"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Josip","family":"Peji\u0107","sequence":"additional","affiliation":[{"name":"Department of Thoracic Surgery, University Hospital Dubrava, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ton\u0107i","family":"Grmoja","sequence":"additional","affiliation":[{"name":"Department of Radiology, University Children\u2019s Hospital Zagreb, Zagreb, Croatia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iva","family":"Buti\u0107","sequence":"additional","affiliation":[{"name":"Department of Microbiology, University Hospital for Infectious Diseases, Zagreb, Croatia"},{"name":"School of Dental Medicine, University of Zagreb, Zagreb, Croatia."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan","family":"Pavi\u0107","sequence":"additional","affiliation":[{"name":"Department of Pulmonology, Allergology, Immunology and Rheumatology"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2024,7,31]]},"reference":[{"key":"R1-20250614","doi-asserted-by":"crossref","first-page":"e1413","DOI":"10.1542\/peds.2007-1897","article-title":"Beyond cat scratch disease: widening spectrum of Bartonella henselae infection.","volume":"121","author":"Florin","year":"2008","journal-title":"Pediatrics"},{"key":"R2-20250614","doi-asserted-by":"crossref","first-page":"1196700","DOI":"10.3389\/fmicb.2023.1196700","article-title":"Advancements in understanding the molecular and immune mechanisms of Bartonella pathogenicity.","volume":"14","author":"Jin","year":"2023","journal-title":"Front Microbiol"},{"key":"R3-20250614","doi-asserted-by":"crossref","first-page":"1438","DOI":"10.3201\/eid2607.200034","article-title":"Atypical manifestations of cat-scratch disease, United States, 2005-2014.","volume":"26","author":"Nawrocki","year":"2020","journal-title":"Emerg Infect Dis"},{"key":"R4-20250614","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1111\/jpc.15304","article-title":"Atypical bartonellosis in children: what do we know?","volume":"57","author":"Lemos","year":"2021","journal-title":"J Paediatr Child Health"},{"key":"R5-20250614","first-page":"4966","article-title":"Cat","volume":"7","author":"Konstantinou","year":"2020","journal-title":"Ijmsci"},{"key":"R6-20250614","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1097\/00006454-199407000-00014","article-title":"Fever, back pain and pleural effusion in a four-year-old boy.","volume":"13","author":"Karanyi","year":"1994","journal-title":"Pediatr Infect Dis J"},{"key":"R7-20250614","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1007\/s004310000697","article-title":"Asymptomatic persistent pulmonary infiltrates in an immunocompetent boy with cat-scratch disease.","volume":"160","author":"Marseglia","year":"2001","journal-title":"Eur J Pediatr"},{"key":"R8-20250614","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1097\/00006454-199506000-00014","article-title":"Pulmonary manifestations of cat-scratch disease; 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