{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T22:27:08Z","timestamp":1770503228897,"version":"3.49.0"},"reference-count":52,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,5]]},"DOI":"10.1097\/inf.0b013e3181660c2e","type":"journal-article","created":{"date-parts":[[2008,4,28]],"date-time":"2008-04-28T07:03:29Z","timestamp":1209366209000},"page":"444-452","source":"Crossref","is-referenced-by-count":34,"title":["Safety of the Intranasal, Trivalent, Live Attenuated Influenza Vaccine (LAIV) in Children With Intermittent Wheezing in an Open-Label Field Trial"],"prefix":"10.1097","volume":"27","author":[{"given":"Manjusha J.","family":"Gaglani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro A.","family":"Piedra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Riggs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gayla","family":"Herschler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Fewlass","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W Paul","family":"Glezen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-12-20210202","doi-asserted-by":"crossref","first-page":"1199","DOI":"10.1016\/j.jaci.2006.08.032","article-title":"Asthma, influenza, and vaccination.","volume":"118","author":"Glezen","year":"2006","journal-title":"J Allergy Clin Immunol"},{"key":"R2-12-20210202","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.3201\/eid1006.030629","article-title":"Respiratory picornaviruses and respiratory syncytial virus as causative agents of acute expiratory wheezing in children.","volume":"10","author":"Jartti","year":"2004","journal-title":"Emerg Infect Dis"},{"key":"R3-12-20210202","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/S0272-5231(21)00289-6","article-title":"Reactive airway disorders in children. Role of respiratory virus infections.","volume":"5","author":"Glezen","year":"1984","journal-title":"Clin Chest Med"},{"key":"R4-12-20210202","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/j.jpeds.2003.11.007","article-title":"Prevalence and characteristics of children at increased risk for complications from influenza, United States, 2000.","volume":"144","author":"Erhart","year":"2004","journal-title":"J Pediatr"},{"key":"R5-12-20210202","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1001\/jama.283.4.499","article-title":"Impact of respiratory virus infections on persons with chronic underlying conditions.","volume":"283","author":"Glezen","year":"2000","journal-title":"JAMA"},{"key":"R6-12-20210202","doi-asserted-by":"crossref","first-page":"856","DOI":"10.1067\/mpd.2000.110445","article-title":"The burden of influenza illness in children with asthma and other chronic medical conditions.","volume":"137","author":"Neuzil","year":"2000","journal-title":"J Pediatr"},{"key":"R7-12-20210202","first-page":"1","article-title":"Prevention and control of influenza. Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2007.","volume":"56","year":"2007","journal-title":"MMWR Recomm Rep"},{"key":"R8-12-20210202","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1053\/spid.2002.122996","article-title":"Rationale and approach to target children with asthma for annual influenza immunization.","volume":"13","author":"Gaglani","year":"2002","journal-title":"Semin Pediatr Infect Dis"},{"key":"R9-12-20210202","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ambp.2005.08.004","article-title":"Influenza vaccination among children with asthma in Medicaid managed care.","volume":"6","author":"Gnanasekaran","year":"2006","journal-title":"Ambul Pediatr"},{"key":"R10-12-20210202","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1001\/archpedi.160.9.966","article-title":"Effect of missed opportunities on influenza vaccination rates among children with asthma.","volume":"160","author":"Dombkowski","year":"2006","journal-title":"Arch Pediatr Adolesc Med"},{"key":"R11-12-20210202","doi-asserted-by":"crossref","first-page":"986","DOI":"10.1001\/archpedi.159.10.986","article-title":"Missed opportunities for influenza vaccination in children with chronic medical conditions.","volume":"159","author":"Daley","year":"2005","journal-title":"Arch Pediatr Adolesc Med"},{"key":"R12-12-20210202","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1016\/j.ambp.2006.04.006","article-title":"Improving influenza vaccination rates for children through year-round scheduling.","volume":"6","author":"Paul","year":"2006","journal-title":"Ambul Pediatr"},{"key":"R13-12-20210202","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1177\/000992280604500303","article-title":"Improving influenza vaccination rates in a pediatric asthma management program by utilization of an electronic medical record.","volume":"45","author":"Martin","year":"2006","journal-title":"Clin Pediatr (Phila)"},{"issue":"1","key":"R14-12-20210202","doi-asserted-by":"crossref","first-page":"e26","DOI":"10.1542\/peds.113.1.e26","article-title":"Identification and recall of children with chronic medical conditions for influenza vaccination.","volume":"113","author":"Daley","year":"2004","journal-title":"Pediatrics"},{"key":"R15-12-20210202","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1097\/00006454-200112000-00012","article-title":"A computerized reminder strategy is effective for annual influenza immunization of children with asthma or reactive airway disease.","volume":"20","author":"Gaglani","year":"2001","journal-title":"Pediatr Infect Dis J"},{"key":"R16-12-20210202","first-page":"193","article-title":"Influenza vaccination coverage among children with asthma-United States, 2004\u201305 influenza season.","volume":"56","year":"2007","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"R17-12-20210202","doi-asserted-by":"crossref","first-page":"1990","DOI":"10.1001\/jama.296.16.1990","article-title":"Vaccine Safety Datalink Team. Safety of trivalent inactivated influenza vaccine in children 6 to 23 months old.","volume":"296","author":"Hambidge","year":"2006","journal-title":"JAMA"},{"key":"R18-12-20210202","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1001\/archpedi.158.11.1031","article-title":"Safety of the trivalent inactivated influenza vaccine among children: a population-based study.","volume":"158","author":"France","year":"2004","journal-title":"Arch Pediatr Adolesc Med"},{"key":"R19-12-20210202","doi-asserted-by":"crossref","first-page":"e821","DOI":"10.1542\/peds.2005-2234","article-title":"The safety of trivalent influenza vaccine among healthy children 6 to 24 months of age.","volume":"117","author":"Goodman","year":"2006","journal-title":"Pediatrics"},{"key":"R20-12-20210202","doi-asserted-by":"crossref","first-page":"1529","DOI":"10.1056\/NEJMoa011961","article-title":"The safety of inactivated influenza vaccine in adults and children with asthma.","volume":"345","year":"2001","journal-title":"N Engl J Med"},{"key":"R21-12-20210202","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1097\/01.inf.0000116292.46143.d6","article-title":"Safety and efficacy of trivalent inactivated influenza vaccine in young children: a summary for the new era of routine vaccination.","volume":"23","author":"Zangwill","year":"2004","journal-title":"Pediatr Infect Dis J"},{"key":"R22-12-20210202","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1542\/peds.2005-0049","article-title":"Effectiveness of the 2003\u20132004 influenza vaccine among children 6 months to 8 years of age, with 1 vs. 2 doses.","volume":"116","author":"Ritzwoller","year":"2005","journal-title":"Pediatrics"},{"key":"R23-12-20210202","doi-asserted-by":"crossref","first-page":"755","DOI":"10.1016\/j.jpeds.2006.06.036","article-title":"Influenza vaccine effectiveness in healthy 6- to 21-month-old children during the 2003\u20132004 season.","volume":"149","author":"Allison","year":"2006","journal-title":"J Pediatr"},{"key":"R24-12-20210202","first-page":"1062","article-title":"Childhood influenza vaccination coverage-United States, 2004\u201305 influenza season.","volume":"55","year":"2006","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"R25-12-20210202","doi-asserted-by":"crossref","first-page":"1405","DOI":"10.1056\/NEJM199805143382002","article-title":"The efficacy of live attenuated, cold-adapted, trivalent, intranasal influenzavirus vaccine in children.","volume":"338","author":"Belshe","year":"1998","journal-title":"N Engl J Med"},{"key":"R26-12-20210202","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/S0022-3476(00)70097-7","article-title":"Efficacy of vaccination with live attenuated, cold-adapted, trivalent, intranasal influenza virus vaccine against a variant (A\/Sydney) not contained in the vaccine.","volume":"136","author":"Belshe","year":"2000","journal-title":"J Pediatr"},{"key":"R27-12-20210202","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1016\/S0264-410X(99)00419-3","article-title":"Estimation of the efficacy of live, attenuated influenza vaccine from a two-year, multi-center vaccine trial: implications for influenza epidemic control.","volume":"18","author":"Longini","year":"2000","journal-title":"Vaccine"},{"key":"R28-12-20210202","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1542\/peds.110.4.662","article-title":"Safety of the trivalent, cold-adapted influenza vaccine in preschool-aged children.","volume":"110","author":"Piedra","year":"2002","journal-title":"Pediatrics"},{"key":"R29-12-20210202","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1097\/01.inf.0000109392.96411.4f","article-title":"Safety of cold-adapted live attenuated influenza vaccine in a large cohort of children and adolescents.","volume":"23","author":"Bergen","year":"2004","journal-title":"Pediatr Infect Dis J"},{"key":"R30-12-20210202","first-page":"1217","article-title":"Notice to readers: expansion of use of live attenuated influenza vaccine (FluMist\u00ae) to children aged 2\u20134 years and other flumist changes for the 2007\u201308 influenza season.","volume":"56","year":"2007","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"R31-12-20210202","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1164\/rccm.200504-525OC","article-title":"Outcome of asthma and wheezing in the first 6 years of life: follow-up through adolescence.","volume":"172","author":"Morgan","year":"2005","journal-title":"Am J Respir Crit Care Med"},{"key":"R32-12-20210202","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1056\/NEJM199501193320301","article-title":"Asthma and wheezing in the first six years of life. The Group Health Medical Associates.","volume":"332","author":"Martinez","year":"1995","journal-title":"N Engl J Med"},{"key":"R33-12-20210202","doi-asserted-by":"crossref","first-page":"e397","DOI":"10.1542\/peds.2004-2258","article-title":"Live attenuated influenza vaccine, trivalent, is safe in healthy children 18 months to 4 years, 5 to 9 years, and 10 to 18 years of age in a community-based, nonrandomized, open-label trial.","volume":"116","author":"Piedra","year":"2005","journal-title":"Pediatrics"},{"key":"R34-12-20210202","doi-asserted-by":"crossref","first-page":"1540","DOI":"10.1016\/j.vaccine.2004.09.025","article-title":"Herd immunity in adults against influenza-related illnesses with use of the trivalent-live attenuated influenza vaccine (CAIV-T) in children.","volume":"23","author":"Piedra","year":"2005","journal-title":"Vaccine"},{"key":"R35-12-20210202","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1001\/archpedi.158.1.65","article-title":"Direct and total effectiveness of the intranasal, live-attenuated, trivalent cold-adapted influenza virus vaccine against the 2000\u20132001 influenza A (H1N1) and B epidemic in healthy children.","volume":"158","author":"Gaglani","year":"2004","journal-title":"Arch Pediatr Adolesc Med"},{"key":"R36-12-20210202","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1093\/aje\/kwg163","article-title":"Estimating efficacy of trivalent, cold-adapted, influenza virus vaccine (CAIV-T) against influenza A (H1N1) and B using surveillance cultures.","volume":"158","author":"Halloran","year":"2003","journal-title":"Am J Epidemiol"},{"key":"R37-12-20210202","doi-asserted-by":"crossref","first-page":"4038","DOI":"10.1016\/j.vaccine.2007.02.060","article-title":"Efficacy of trivalent, cold-adapted, influenza virus vaccine against influenza A (Fujian), a drift variant, during 2003\u20132004.","volume":"25","author":"Halloran","year":"2007","journal-title":"Vaccine"},{"key":"R38-12-20210202","doi-asserted-by":"crossref","first-page":"e553","DOI":"10.1542\/peds.2006-2836","article-title":"Trivalent live attenuated intranasal influenza vaccine administered during the 2003\u20132004 influenza type A (H3N2) outbreak provided immediate, direct, and indirect protection in children.","volume":"120","author":"Piedra","year":"2007","journal-title":"Pediatrics"},{"key":"R39-12-20210202","doi-asserted-by":"crossref","first-page":"1393","DOI":"10.1016\/0895-4356(95)00065-8","article-title":"Use of an automated prescription database to identify individuals with asthma.","volume":"48","author":"Osborne","year":"1995","journal-title":"J Clin Epidemiol"},{"key":"R40-12-20210202","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1542\/peds.89.4.640","article-title":"No increased risk for invasive bacterial infection found following diphtheria-tetanus-pertussis immunization.","volume":"89","author":"Griffin","year":"1992","journal-title":"Pediatrics"},{"key":"R41-12-20210202","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1542\/peds.88.5.881","article-title":"Risk of seizures after measles-mumps-rubella immunization.","volume":"88","author":"Griffin","year":"1991","journal-title":"Pediatrics"},{"key":"R42-12-20210202","article-title":"Practical Biostatistical Methods.","author":"Selvin","year":"1995"},{"key":"R43-12-20210202","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1089\/hum.1992.3.6-657","article-title":"The challenge of follow-up for clinical trials of somatic gene therapy.","volume":"3","author":"Ledley","year":"1992","journal-title":"Hum Gene Ther"},{"key":"R44-12-20210202","first-page":"149","article-title":"Multivariate cohort analysis.","volume":"67","author":"Breslow","year":"1985","journal-title":"Natl Cancer Inst Monogr"},{"key":"R45-12-20210202","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1097\/00006454-200201000-00010","article-title":"Safety and tolerability of cold-adapted influenza virus vaccine in children and adolescents with asthma.","volume":"21","author":"Redding","year":"2002","journal-title":"Pediatr Infect Dis J"},{"key":"R46-12-20210202","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1097\/01.inf.0000220229.51531.47","article-title":"A randomized, double-blind study of the safety, transmissibility and phenotypic and genotypic stability of cold-adapted influenza virus vaccine.","volume":"25","author":"Vesikari","year":"2006","journal-title":"Pediatr Infect Dis J"},{"key":"R47-12-20210202","doi-asserted-by":"crossref","first-page":"2523","DOI":"10.1056\/NEJMoa055414","article-title":"Effectiveness of school-based influenza vaccination.","volume":"355","author":"King","year":"2006","journal-title":"N Engl J Med"},{"key":"R48-12-20210202","doi-asserted-by":"crossref","first-page":"2298","DOI":"10.1542\/peds.2006-0725","article-title":"Safety, efficacy, and effectiveness of cold-adapted influenza vaccine-trivalent against community-acquired, culture-confirmed influenza in young children attending day care.","volume":"118","author":"Vesikari","year":"2006","journal-title":"Pediatrics"},{"key":"R49-12-20210202","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1097\/01.inf.0000237829.66310.85","article-title":"Superior relative efficacy of live attenuated influenza vaccine compared with inactivated influenza vaccine in young children with recurrent respiratory tract infections.","volume":"25","author":"Ashkenazi","year":"2006","journal-title":"Pediatr Infect Dis J"},{"key":"R50-12-20210202","doi-asserted-by":"crossref","first-page":"2720","DOI":"10.1001\/jama.294.21.2720","article-title":"Adverse events reported following live, cold-adapted, intranasal influenza vaccine.","volume":"294","author":"Izurieta","year":"2005","journal-title":"JAMA"},{"key":"R51-12-20210202","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1097\/01.inf.0000237797.14283.cf","article-title":"Comparison of the efficacy and safety of live attenuated cold-adapted influenza vaccine, trivalent, with trivalent inactivated influenza virus vaccine in children and adolescents with asthma.","volume":"25","author":"Fleming","year":"2006","journal-title":"Pediatr Infect Dis J"},{"key":"R52-12-20210202","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1056\/NEJMoa065368","article-title":"Live attenuated versus inactivated influenza vaccine in infants and young children.","volume":"356","author":"Belshe","year":"2007","journal-title":"N Engl J Med"}],"container-title":["Pediatric Infectious Disease Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/INF.0b013e3181660c2e","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,5,17]],"date-time":"2023-05-17T23:28:40Z","timestamp":1684366120000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00006454-200805000-00012"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5]]},"references-count":52,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1097\/inf.0b013e3181660c2e","relation":{},"ISSN":["0891-3668"],"issn-type":[{"value":"0891-3668","type":"print"}],"subject":[],"published":{"date-parts":[[2008,5]]}}}