{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:15:29Z","timestamp":1786119329225,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,12]]},"DOI":"10.1097\/inf.0b013e3181af37ee","type":"journal-article","created":{"date-parts":[[2009,11,24]],"date-time":"2009-11-24T03:16:26Z","timestamp":1259032586000},"page":"1121-1123","source":"Crossref","is-referenced-by-count":30,"title":["GENE POLYMORPHISM OF IFNG +874 T\/A AND TLR4 +896 A\/G AND RECURRENT INFECTIONS AND WHEEZING IN TODDLERS WITH HISTORY OF BRONCHIOLITIS"],"prefix":"10.1097","volume":"28","author":[{"given":"Kirsi","family":"Nuolivirta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mikko","family":"Hurme","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne","family":"Halkosalo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petri","family":"Koponen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti","family":"Korppi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timo","family":"Vesikari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merja","family":"Helminen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-23-20210202","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1067\/mai.2003.33","article-title":"Rhinovirus- induced wheezing in infancy\u2013the first sign on childhood asthma?","volume":"111","author":"Kotaniemi-Syrj\u00e4nen","year":"2003","journal-title":"J Allergy Clin Immunol"},{"key":"R2-23-20210202","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/ppul.20793","article-title":"IL-10 gene polymorphism at \u22121082 A\/G is associated with severe rhinovirus bronchiolitis in infants.","volume":"43","author":"Helminen","year":"2008","journal-title":"Pediatr Pulmonol"},{"key":"R3-23-20210202","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1111\/j.1365-2249.2006.03030.x","article-title":"Lipopolysaccharide hyporesponsiveness as a risk factor for intensive care unit hospitalization in infants with respiratory syncycitial virus bronchiolitis.","volume":"144","author":"Mandelberg","year":"2006","journal-title":"Clin Exp Immunol"},{"key":"R4-23-20210202","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/80833","article-title":"Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus.","volume":"1","author":"Kurt-Jones","year":"2000","journal-title":"Nat Immunol"},{"key":"R5-23-20210202","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1016\/S0198-8859(00)00167-1","article-title":"A single nucleotide polymorphism in the first intron of the human IFN-gamma gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production.","volume":"61","author":"Pravica","year":"2000","journal-title":"Hum Immunol"},{"key":"R6-23-20210202","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1097\/00007890-200103150-00018","article-title":"Association of polymorphisms in the human interferon-gamma and interleukin-10 gene with acute and chronic kidney transplant outcome: the cytokine effect on transplantation.","volume":"71","author":"Asderakis","year":"2001","journal-title":"Transplantation"},{"key":"R7-23-20210202","doi-asserted-by":"crossref","first-page":"854","DOI":"10.1086\/432484","article-title":"Evidence that interferon-gamma plays a protective role during cerebral malaria.","volume":"192","author":"Cabantous","year":"2005","journal-title":"J Infect Dis"},{"key":"R8-23-20210202","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1002\/hep.1840360618","article-title":"Genetic polymorphisms in interferon pathway and response to interferon treatment in hepatitis B patients: a pilot study.","volume":"36","author":"King","year":"2002","journal-title":"Hepatology"},{"key":"R9-23-20210202","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1152\/japplphysiol.00934.2001","article-title":"Double-stranded RNA causes airway hyperreactivity and neuronal M2 muscarinic receptor dysfunction.","volume":"92","author":"Bowerfind","year":"2002","journal-title":"J Appl Physiol"},{"key":"R10-23-20210202","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1001\/archinte.162.9.1028","article-title":"Relevance of mutations in the TLR4 receptor in patients with gram-negative septic shock.","volume":"162","author":"Lorenz","year":"2002","journal-title":"Arch Intern Med"}],"container-title":["Pediatric Infectious Disease Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/INF.0b013e3181af37ee","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:04:04Z","timestamp":1786039444000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00006454-200912000-00023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,12]]},"references-count":10,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1097\/inf.0b013e3181af37ee","relation":{},"ISSN":["0891-3668"],"issn-type":[{"value":"0891-3668","type":"print"}],"subject":[],"published":{"date-parts":[[2009,12]]}}}