{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T21:18:51Z","timestamp":1792012731875,"version":"4.4.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2017,3,1]],"date-time":"2017-03-01T00:00:00Z","timestamp":1488326400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/ http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,3]]},"abstract":"<jats:sec>\n            <jats:title>Introduction:<\/jats:title>\n            <jats:p>In this cross-sectional study, we aimed to determine the prevalence and characteristics of chronic ocular itch in an outpatient ophthalmology and optometry clinic.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>Four hundred patients from an outpatient ophthalmology and optometry clinic were enrolled. The presence and characteristics of chronic ocular itch were assessed by a questionnaire. Data regarding ophthalmologic, dermatologic, and systemic conditions as well as current medications were extracted from medical records.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>Chronic ocular itch was present in 118 (29.5%) of 400 participants. Chronic ocular pruritus was significantly more prevalent in females [<jats:italic toggle=\"yes\">P<\/jats:italic>=0.015; odds ratio (OR)=1.8; 95% confidence interval (CI), 1.1\u20132.8] and was significantly associated with the presence of allergic conjunctivitis [51.8% (n=45); <jats:italic toggle=\"yes\">P<\/jats:italic>&lt;0.001; OR=5.0; 95% CI, 3.0\u20138.3], dry eye syndrome [40.1% (75); <jats:italic toggle=\"yes\">P<\/jats:italic>&lt;0.001; OR=2.6; 95% CI, 1.7\u20134.1], blepharitis [43.8% (n=21); <jats:italic toggle=\"yes\">P<\/jats:italic>=0.021; OR=2.0; 95% CI, 1.1\u20133.8], and atopic dermatitis [50.0% (n=10); <jats:italic toggle=\"yes\">P<\/jats:italic>=0.023; OR=2.6; 95% CI, 1.1\u20135.8]. Chronic ocular itch was not significantly associated with systemic conditions, or the use of prescribed ophthalmologic medications.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Discussion:<\/jats:title>\n            <jats:p>Chronic ocular itch is common and may be related to ophthalmologic or dermatologic pathologies. The present findings highlight the importance of identifying and managing this uncomfortable symptom that may negatively impact the quality of life and sleep of affected patients.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/itx.0000000000000004","type":"journal-article","created":{"date-parts":[[2017,3,7]],"date-time":"2017-03-07T15:31:31Z","timestamp":1488900691000},"page":"e4-e4","source":"Crossref","is-referenced-by-count":6,"title":["The prevalence and characteristics of chronic ocular itch: a cross-sectional survey"],"prefix":"10.1097","volume":"2","author":[{"given":"Carolyn","family":"Stull","sequence":"first","affiliation":[{"name":"Dermatology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Valdes-Rodriguez","sequence":"additional","affiliation":[{"name":"Dermatology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian M.","family":"Shafer","sequence":"additional","affiliation":[{"name":"Ophthalmology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alina","family":"Shevchenko","sequence":"additional","affiliation":[{"name":"Dermatology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leigh A.","family":"Nattkemper","sequence":"additional","affiliation":[{"name":"Dermatology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiong-Huak","family":"Chan","sequence":"additional","affiliation":[{"name":"Biostatistics Unit, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sydney","family":"Tabaac","sequence":"additional","affiliation":[{"name":"Ophthalmology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin J.","family":"Schardt","sequence":"additional","affiliation":[{"name":"Ophthalmology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dany M.","family":"Najjar","sequence":"additional","affiliation":[{"name":"Ophthalmology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William J.","family":"Foster","sequence":"additional","affiliation":[{"name":"Ophthalmology, Lewis Katz School of Medicine at Temple University, Philadelphia, PA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gil","family":"Yosipovitch","sequence":"additional","affiliation":[{"name":"Department of Dermatology and Itch Center, University of Miami Miller School of Medicine, Miami, FL"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20230817","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.anai.2012.01.006","article-title":"Allergic conjunctivitis and dry 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