{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,10,2]],"date-time":"2024-10-02T04:20:47Z","timestamp":1727842847466},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Some patients with breast cancer submitted to breast-conserving surgery might benefit from a postlumpectomy imaging examination previously to radiation therapy. This aims to document the complete removal of cancer and might be accomplished using mammogram with breast and axillary ultrasonography. These modalities study not only the affected side but also the contralateral side. In fact, it is well-documented that women with breast cancer have an increased risk for contralateral breast cancer. Thus, we intended to evaluate the value of postlumpectomy imaging undertaken before adjuvant radiotherapy regarding the evaluation of the contralateral breast and axilla.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>In this retrospective study, medical records for patients with breast cancer submitted to breast-conserving surgery and referred to our radiotherapy unit between 2018 and 2019 were reviewed. All patients had to be submitted to bilateral mammogram with breast and axillary ultrasonography previously to radiotherapy. Patients with bilateral disease or with a history of breast cancer were excluded.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>One thousand two hundred forty patients were analyzed. 19 (1.5%) had suspicious findings for contralateral breast disease, and 8 (0.6%) had a re-excision positive for residual malignancy. Higher age, invasive lobular carcinoma associated or not with lobular carcinoma in situ, and presence of lobular carcinoma in situ were associated with an increased risk for residual disease.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>Contralateral evaluation as part of postlumpectomy imaging revealed itself useful at detecting contralateral cancer, with some demographic and clinical features being associated with an increased risk for residual disease.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/j.pbj.0000000000000244","type":"journal-article","created":{"date-parts":[[2024,2,12]],"date-time":"2024-02-12T22:01:31Z","timestamp":1707775291000},"update-policy":"http:\/\/dx.doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Postlumpectomy imaging: is there a role for the study of the contralateral breast?\u2014a retrospective cohort"],"prefix":"10.1097","volume":"9","author":[{"given":"Andr\u00e9 M.","family":"Pires","sequence":"first","affiliation":[{"name":"Radiation Oncology Department, Portuguese Institute of Oncology of Porto, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00e9ssica R.","family":"Rodrigues","sequence":"additional","affiliation":[{"name":"Cancer Epidemiology Group, Portuguese Institute of Oncology of Porto, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helena G.","family":"Pereira","sequence":"additional","affiliation":[{"name":"Radiation Oncology Department, Portuguese Institute of Oncology of Porto, Porto, Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2024,1]]},"reference":[{"key":"R1-20241001","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1016\/0360-3016(86)90028-3","article-title":"Results of re-excisional biopsy of the primary 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characteristics of specimen radiography for margin assessment for ductal carcinoma in situ: a systematic review","volume":"166","author":"Versteegden","year":"2017","journal-title":"Breast Cancer Res Treat."},{"key":"R5-20241001","first-page":"855","article-title":"Epidemiology of contralateral breast cancer","volume":"8","author":"Chen","year":"1999","journal-title":"Cancer Epidemiol Biomarkers Prev."},{"issue":"suppl 15","key":"R6-20241001","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1200\/JCO.2019.37.15_suppl.1549","article-title":"Contralateral breast cancer risk according to first breast cancer characteristics among United States women from 1992 to 2015","volume":"37","author":"Ramin","year":"2019","journal-title":"J Clin Oncol."},{"key":"R7-20241001","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1007\/s10549-007-9709-2","article-title":"The impact of adjuvant therapy on contralateral breast cancer risk and the prognostic significance of contralateral breast cancer: a population based study in The Netherlands","volume":"110","author":"Schaapveld","year":"2008","journal-title":"Breast Cancer Res Treat."},{"key":"R8-20241001","doi-asserted-by":"crossref","first-page":"4210","DOI":"10.1200\/JCO.2006.10.5056","article-title":"Incidence and prognosis of synchronous and metachronous bilateral breast cancer","volume":"25","author":"Hartman","year":"2007","journal-title":"J Clin Oncol."},{"issue":"suppl 3","key":"R9-20241001","doi-asserted-by":"crossref","first-page":"S412","DOI":"10.1245\/s10434-015-4835-2","article-title":"Survival outcomes and pathologic features among breast cancer patients who have developed a contralateral breast cancer","volume":"22","author":"Liederbach","year":"2015","journal-title":"Ann Surg Oncol."}],"container-title":["Porto Biomedical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/j.pbj.0000000000000244","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T19:04:49Z","timestamp":1727809489000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/j.pbj.0000000000000244"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1097\/j.pbj.0000000000000244","relation":{},"ISSN":["2444-8664"],"issn-type":[{"type":"electronic","value":"2444-8664"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2021-02-27","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-12-30","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}