{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T21:54:30Z","timestamp":1790114070678,"version":"4.0.1"},"reference-count":38,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2010,5,1]],"date-time":"2010-05-01T00:00:00Z","timestamp":1272672000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The American Journal of Geriatric Psychiatry"],"published-print":{"date-parts":[[2010,5]]},"DOI":"10.1097\/jgp.0b013e3181c294ac","type":"journal-article","created":{"date-parts":[[2010,3,23]],"date-time":"2010-03-23T06:44:31Z","timestamp":1269326671000},"page":"404-412","source":"Crossref","is-referenced-by-count":38,"title":["Effect of Age on the Frequency of Anxiety Disorders in Major Depression With Psychotic Features"],"prefix":"10.1016","volume":"18","author":[{"given":"Alastair J.","family":"Flint","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Peasley-Miklus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eros","family":"Papademetriou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barnett S.","family":"Meyers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benoit H.","family":"Mulsant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony J.","family":"Rothschild","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellen M.","family":"Whyte","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1097\/JGP.0b013e3181c294ac_bib1","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1001\/archpsyc.1988.01800350011002","article-title":"One-month prevalence of mental disorders in the United States: based on five epidemiologic catchment area sites","volume":"45","author":"Regier","year":"1988","journal-title":"Arch Gen Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib2","series-title":"Psychiatric Disorders in America: The Epidemiological Catchment Area Study","first-page":"180","article-title":"Generalised anxiety disorder","author":"Blazer","year":"1991"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib3","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1001\/archpsyc.62.6.593","article-title":"Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication","volume":"62","author":"Kessler","year":"2005","journal-title":"Arch Gen Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib4","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1192\/bjp.178.2.145","article-title":"Prevalence, comorbidity, disability and service utilization. Overview of the Australian National Mental Health Survey","volume":"178","author":"Andrews","year":"2001","journal-title":"Br J Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib5","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1080\/j.1440-1614.2006.01903.x","article-title":"Prevalence, interference with life and severity of 12 month DSM-IV disorders in Te Rau Hinengaro: the New Zealand Mental Health Survey","volume":"40","author":"Wells","year":"2006","journal-title":"Austr N Z J Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib6","first-page":"31","article-title":"Epidemiology and comorbidity of anxiety disorders in late-life: implications for treatment","volume":"4","author":"Flint","year":"1997","journal-title":"Clin Neurosci"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib7","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/S0887-6185(99)00044-4","article-title":"Assessment of anxiety in older adults: current status","volume":"14","author":"Kogan","year":"2000","journal-title":"J Anxiety Dis"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib8","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/S0005-7916(97)00025-6","article-title":"Prevalence of anxiety disorders in elderly adults: a critical analysis","volume":"28","author":"Fuentes","year":"1997","journal-title":"J Behav Ther Exp Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib9","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1080\/j.1440-1614.2006.01861.x","article-title":"Do older Australians truly have lower rates of anxiety and depression? A critique of the 1997 National Survey of Mental Health and Wellbeing","volume":"40","author":"O'Connor","year":"2006","journal-title":"Aust N Z J Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib10","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1192\/S0007125000293483","article-title":"Prevalence of anxiety disorders and their comorbidity with mood and addictive disorders","volume":"173","author":"Regier","year":"1998","journal-title":"Br J Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib11","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1001\/archpsyc.62.6.617","article-title":"Prevalence, severity and comorbidity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication","volume":"62","author":"Kessler","year":"2005","journal-title":"Arch Gen Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib12","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1176\/ajp.151.5.640","article-title":"Epidemiology and comorbidity of anxiety disorders in the elderly","volume":"151","author":"Flint","year":"1994","journal-title":"Am J Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib13","doi-asserted-by":"crossref","first-page":"852","DOI":"10.1176\/appi.ajgp.13.10.852","article-title":"Age-related characteristics of depression: a preliminary STAR*D report","volume":"13","author":"Husain","year":"2005","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib14","doi-asserted-by":"crossref","first-page":"838","DOI":"10.1001\/archgenpsychiatry.2009.79","article-title":"A double-blind randomized controlled trial of olanzapine plus sertraline versus olanzapine plus placebo for psychotic depression: the study of pharmacotherapy of psychotic depression (STOP-PD)","volume":"66","author":"Meyers","year":"2009","journal-title":"Arch Gen Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib15","series-title":"Structured Clinical Interview for DSM-IV-TR Axis I Disorders-Patient Edition (SCID-I\/P)","author":"First","year":"2001"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib16","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1017\/S0033291701004184","article-title":"A general population comparison of the Composite International Diagnostic Interview (CIDI) and the Schedules for Clinical Assessment in Neuropsychiatry (SCAN)","volume":"31","author":"Brugha","year":"2001","journal-title":"Psychol Med"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib17","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1136\/jnnp.23.1.56","article-title":"A rating scale for depression","volume":"23","author":"Hamilton","year":"1960","journal-title":"J Neurol Neurosurg Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib18","series-title":"Schedule for Affective Disorders and Schizophrenia","author":"Spitzer","year":"1979"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib19","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1016\/j.biopsych.2006.05.033","article-title":"A delusion assessment scale for psychotic major depression: reliability, validity, and utility","volume":"60","author":"Meyers","year":"2006","journal-title":"Biol Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib20","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/0022-3956(75)90026-6","article-title":"\u201cMini-mental state.\u201d A practical method for grading the cognitive state of patients for the clinician","volume":"12","author":"Folstein","year":"1975","journal-title":"J Psychiatr Res"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib21","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/0165-1781(92)90005-N","article-title":"Rating chronic medical illness burden in geropsychiatric practice and research: application of the Cumulative Illness Rating Scale","volume":"41","author":"Miller","year":"1992","journal-title":"Psychiatry Res"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib22","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/0010-440X(94)90025-6","article-title":"Reliability of the Structured Clinical Interview for DSM-III-R: an evaluative review","volume":"35","author":"Segal","year":"1994","journal-title":"Compr Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib23","doi-asserted-by":"crossref","first-page":"799","DOI":"10.2466\/pr0.1962.10.3.799","article-title":"The Brief Psychiatric Rating Scale","volume":"10","author":"Overall","year":"1962","journal-title":"Psychol Rep"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib24","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1176\/appi.ajp.159.4.620","article-title":"Risk factors for 12-month comorbidity of mood, anxiety, and substance use disorders: findings from the Netherlands Mental Health Survey and Incidence Study","volume":"159","author":"De Graaf","year":"2002","journal-title":"Am J Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib25","doi-asserted-by":"crossref","first-page":"1747","DOI":"10.1017\/S0033291705006069","article-title":"Prevalence, correlates, co-morbidity, and comparative disability of DSM-IV generalized anxiety disorder in the USA: results from the National Epidemiologic Survey on Alcohol and Related Conditions","volume":"35","author":"Grant","year":"2005","journal-title":"Psychol Med"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib26","doi-asserted-by":"crossref","first-page":"363","DOI":"10.4088\/JCP.v67n0305","article-title":"The epidemiology of DSM-IV panic disorder and agoraphobia in the United States: results from the National Epidemiologic Survey on Alcohol and Related Conditions","volume":"67","author":"Grant","year":"2006","journal-title":"J Clin Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib27","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1176\/appi.ajgp.13.1.3","article-title":"Anxiety and its disorders in late life: moving the field forward","volume":"13","author":"Flint","year":"2005","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib28","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1176\/appi.ajgp.13.1.7","article-title":"Affective correlates of fear of falling in elderly persons","volume":"13","author":"Gagnon","year":"2005","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib29","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1017\/S0033291798008150","article-title":"Age differences in depression and anxiety symptoms: a structural equation modeling analysis of data from a general population sample","volume":"29","author":"Christensen","year":"1999","journal-title":"Psychol Med"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib30","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1176\/appi.ajp.162.6.1179","article-title":"Influence of psychiatric comorbidity on recovery and recurrence in generalized anxiety disorder, social phobia, and panic disorder: a 12-year prospective study","volume":"162","author":"Bruce","year":"2005","journal-title":"Am J Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib31","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/S0010-440X(00)90140-8","article-title":"Anxiety disorders in major depression","volume":"41","author":"Fava","year":"2000","journal-title":"Compr Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib32","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1176\/appi.ajp.157.8.1337","article-title":"Frequency of anxiety disorders in psychiatric outpatients with major depressive disorder","volume":"157","author":"Zimmerman","year":"2000","journal-title":"Am J Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib33","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1080\/00048670701392817","article-title":"Age shall not weary them: mental health in the middle-aged and the elderly","volume":"41","author":"Trollor","year":"2007","journal-title":"Aust N Z J Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib34","doi-asserted-by":"crossref","first-page":"101","DOI":"10.2165\/00002512-200522020-00002","article-title":"Generalised anxiety disorder in elderly patients. Epidemiology, diagnosis and treatment options","volume":"22","author":"Flint","year":"2005","journal-title":"Drugs Aging"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib35","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1002\/da.20491","article-title":"The nosologic relationship between generalized anxiety disorder and major depression","volume":"25","author":"Hettema","year":"2008","journal-title":"Depress Anxiety"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib36","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1002\/(SICI)1099-1166(1998100)13:10<717::AID-GPS857>3.0.CO;2-M","article-title":"Anxiety disorders in later life: a report from the longitudinal aging study Amsterdam","volume":"13","author":"Beekman","year":"1998","journal-title":"Int J Geriatr Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib37","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1176\/appi.ajp.157.5.722","article-title":"Comorbid anxiety disorders in depressed elderly patients","volume":"157","author":"Lenze","year":"2000","journal-title":"Am J Psychiatry"},{"key":"10.1097\/JGP.0b013e3181c294ac_bib38","doi-asserted-by":"crossref","first-page":"126","DOI":"10.4088\/JCP.v63n0207","article-title":"Current comorbidity of psychiatric disorders among DSM-IV major depressive disorder patients in psychiatric care in the Vantaa Depression Study","volume":"63","author":"Melartin","year":"2002","journal-title":"J Clin Psychiatry"}],"container-title":["The American Journal of Geriatric Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064748112602061?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1064748112602061?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,27]],"date-time":"2019-05-27T13:04:24Z","timestamp":1558962264000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1064748112602061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,5]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2010,5]]}},"alternative-id":["S1064748112602061"],"URL":"https:\/\/doi.org\/10.1097\/jgp.0b013e3181c294ac","relation":{},"ISSN":["1064-7481"],"issn-type":[{"value":"1064-7481","type":"print"}],"subject":[],"published":{"date-parts":[[2010,5]]}}}