{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:33:04Z","timestamp":1790130784601,"version":"4.0.1"},"reference-count":59,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,7]]},"DOI":"10.1097\/jsm.0b013e31817e34f8","type":"journal-article","created":{"date-parts":[[2009,3,5]],"date-time":"2009-03-05T19:28:25Z","timestamp":1236281305000},"page":"309-315","source":"Crossref","is-referenced-by-count":74,"title":["Mononucleosis and Athletic Participation: An Evidence-Based Subject Review"],"prefix":"10.1097","volume":"18","author":[{"given":"Margot","family":"Putukian","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francis G","family":"O'Connor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Stricker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"McGrew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert G","family":"Hosey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven M","family":"Gordon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Kinderknecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vesna","family":"Kriss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Landry","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-1-20210128","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1093\/clinids\/19.1.152","article-title":"Life-threatening infectious mononucleosis: is it correlated with virus-induced T cell proliferation?","volume":"19","author":"Baumgarten","year":"1994","journal-title":"J Clin Infect Dis"},{"key":"R2-1-20210128","doi-asserted-by":"crossref","first-page":"206","DOI":"10.3928\/0090-4481-19910401-10","article-title":"Infectious mononucleosis in adolescents.","volume":"20","author":"Chetham","year":"1991","journal-title":"Pediatr Ann"},{"key":"R3-1-20210128","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1056\/NEJM197002122820704","article-title":"Prevalence, incidence and persistence of EB virus antibody in young adults.","volume":"282","author":"Niederman","year":"1970","journal-title":"N Engl J Med"},{"key":"R4-1-20210128","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1093\/oxfordjournals.aje.a121444","article-title":"Infectious mononucleosis; epidemiological patterns at United States colleges and universities.","volume":"96","author":"Brodsky","year":"1972","journal-title":"Am J Epidemiol"},{"key":"R5-1-20210128","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1177\/036354658201000308","article-title":"Infectious mononucleosis in the athlete. Diagnosis, complications, and management.","volume":"10","author":"Maki","year":"1982","journal-title":"Am J Sports Med"},{"key":"R8-1-20210128","first-page":"505","article-title":"Infectious mononucleosis.","volume":"96","author":"Hoagland","year":"1975","journal-title":"Prim Care"},{"key":"R13-1-20210128","first-page":"234","article-title":"Prospective study of the natural history of infectious mononucleosis caused by Epstein-Barr virus.","volume":"14","author":"Rea","year":"2001","journal-title":"J Am Board Fam Pract"},{"key":"R14-1-20210128","first-page":"1279","article-title":"Epstein-Barr virus infectious mononucleosis.","volume":"70","author":"Ebell","year":"2004","journal-title":"Am Fam Physician"},{"key":"R15-1-20210128","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.csm.2004.02.005","article-title":"Infectious mononucleosis: return to play.","volume":"23","author":"Auwaerter","year":"2004","journal-title":"Clin Sports Med"},{"key":"R16-1-20210128","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1097\/00007611-197704000-00021","article-title":"Predictors of the duration of infectious mononucleosis.","volume":"70","author":"Chreitin","year":"1977","journal-title":"South Med J"},{"key":"R17-1-20210128","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1097\/01.jsm.0000187077.82230.64","article-title":"Determination of safe return to play for athletes recovering from infectious mononucleosis: a review of the literature.","volume":"15","author":"Waninger","year":"2005","journal-title":"Clin J Sports Med"},{"key":"R18-1-20210128","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/0002-9343(91)90188-4","article-title":"The bedside assessment of splenic enlargement.","volume":"91","author":"Barkun","year":"1991","journal-title":"Am J Med"},{"key":"R19-1-20210128","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1001\/jama.1993.03510180088040","article-title":"The rational clinical examination. Does this patient have splenomegaly?","volume":"270","author":"Grover","year":"1993","journal-title":"JAMA"},{"key":"R20-1-20210128","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1001\/archinte.1974.00320190125018","article-title":"Correlation of liver and spleen size. Determinations by nuclear medicine studies and physical examination.","volume":"134","author":"Halpern","year":"1974","journal-title":"Arch Intern Med"},{"key":"R21-1-20210128","first-page":"91","article-title":"Rupture of the spleen in infectious mononucleosis.","volume":"10","author":"Garfield","year":"1959","journal-title":"US Armed Forces Med J"},{"key":"R22-1-20210128","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1182\/blood.V1.4.317.317","article-title":"Rupture of the spleen in infectious mononucleosis: a clinicopathologic report of seven cases.","volume":"1","author":"Smith","year":"1946","journal-title":"Blood"},{"key":"R23-1-20210128","doi-asserted-by":"crossref","first-page":"43","DOI":"10.3810\/psm.2002.11.529","article-title":"Infectious mononucleosis in active patients.","volume":"30","author":"Auwaerter","year":"2002","journal-title":"Phys Sportsmed"},{"key":"R24-1-20210128","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1128\/JCM.32.1.259-261.1994","article-title":"Comparative evaluation of nine kits for rapid diagnosis of infectious mononucleosis and Epstein-Barr virus-specific serology.","volume":"32","author":"Linderholm","year":"1994","journal-title":"J Clin Microbiol"},{"key":"R26-1-20210128","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1128\/CDLI.7.3.451-456.2000","article-title":"Evaluation of 12 commercial tests for detection of Epstein-Barr virus-specific and heterophile antibodies.","volume":"7","author":"Bruu","year":"2000","journal-title":"Clin Diagn Lab Immunol"},{"key":"R27-1-20210128","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0928-0197(96)00245-0","article-title":"Evaluation of six commercially available kits using purified heterophile antigen for the rapid diagnosis of infectious mononucleosis compared with Epstein-Barr virus-specific serology.","volume":"7","author":"Elgh","year":"1996","journal-title":"Clin Diagn Virol"},{"key":"R28-1-20210128","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1017\/S0950268803008550","article-title":"Clinical and laboratory presentation of EBV positive infectious mononucleosis in young adults.","volume":"131","author":"Grotto","year":"2003","journal-title":"Epidemiol Infect"},{"key":"R29-1-20210128","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0025-7125(16)30166-3","article-title":"Infectious disease in athletes.","volume":"78","author":"Sevier","year":"1994","journal-title":"Med Clin North Am"},{"key":"R30-1-20210128","first-page":"195","article-title":"Medical complications of infectious mononucleosis.","volume":"30","author":"Murray","year":"1984","journal-title":"Am Fam Physician"},{"key":"R31-1-20210128","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/0887-8994(94)90021-3","article-title":"Neurologic complications of infectious mononucleosis.","volume":"10","author":"Connely","year":"1994","journal-title":"Pediatr Neurol"},{"key":"R33-1-20210128","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1097\/00008480-200006000-00016","article-title":"Acute complications of Ebstein-Barr virus infectious mononucleosis.","volume":"12","author":"Jensen","year":"2000","journal-title":"Curr Opin Pediatr"},{"key":"R34-1-20210128","first-page":"175","article-title":"Spontaneous splenic rupture in infectious mononucleosis: a review.","volume":"70","author":"Asgari","year":"1997","journal-title":"Yale J Biol Med"},{"key":"R35-1-20210128","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/S0025-6196(12)60822-2","article-title":"Spontaneous rupture of the spleen due to infectious mononucleosis.","volume":"67","author":"Farley","year":"1992","journal-title":"Mayo Clin Proc"},{"key":"R36-1-20210128","first-page":"217","article-title":"The ruptured spleen in college athletes: a preliminary report.","volume":"26","author":"Frelinger","year":"1978","journal-title":"J Am College Health Assoc"},{"key":"R37-1-20210128","doi-asserted-by":"crossref","first-page":"111","DOI":"10.2214\/ajr.136.1.111","article-title":"Spontaneous splenic rupture in infectious mononucleosis: sonographic diagnosis and follow-up.","volume":"136","author":"Johnson","year":"1981","journal-title":"Am J Roentgenol"},{"key":"R38-1-20210128","first-page":"601","article-title":"Spontaneous splenic rupture following infectious mononucleosis.","volume":"56","author":"Safran","year":"1990","journal-title":"Am Surg"},{"key":"R39-1-20210128","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1001\/archsurg.1967.01330090043010","article-title":"Ruptured spleen on infectious mononucleosis.","volume":"94","author":"Sakulsky","year":"1967","journal-title":"Arch Surg"},{"key":"R40-1-20210128","doi-asserted-by":"crossref","first-page":"289","DOI":"10.2214\/ajr.176.2.1760289","article-title":"Estimated risks of radiation induced fatal cancer from pediatric CT.","volume":"176","author":"Brenner","year":"2001","journal-title":"Am J Roentgenol"},{"key":"R41-1-20210128","doi-asserted-by":"crossref","first-page":"303","DOI":"10.2214\/ajr.176.2.1760303","article-title":"Minimizing radiation dose for pediatric body CT: applications of single detector helical CT.","volume":"176","author":"Donnelly","year":"2001","journal-title":"Am J Roentgenol"},{"key":"R42-1-20210128","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1007\/s00247-002-0774-8","article-title":"Lessons we have learned from our children: cancer risks from diagnostic radiology.","volume":"32","author":"Hall","year":"2002","journal-title":"Pediatr Radiol"},{"key":"R43-1-20210128","doi-asserted-by":"crossref","first-page":"19","DOI":"10.7863\/jum.1984.3.1.19","article-title":"Determination of a splenic volumetric index by ultrasonic scanning.","volume":"3","author":"Pietri","year":"1984","journal-title":"J Ultrasound Med"},{"key":"R44-1-20210128","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1259\/bjr.75.895.750573","article-title":"Spleen size: how well do linear ultrasound measurements correlate with three-dimensional CT volume assessments?","volume":"75","author":"Lamb","year":"2002","journal-title":"Br J Radiol"},{"key":"R48-1-20210128","doi-asserted-by":"crossref","first-page":"345","DOI":"10.7863\/jum.1997.16.5.345","article-title":"Normal splenic size in a Chinese population.","volume":"16","author":"Loftus","year":"1997","journal-title":"J Ultrasound Med"},{"key":"R49-1-20210128","doi-asserted-by":"crossref","first-page":"1693","DOI":"10.2214\/ajr.171.6.9843315","article-title":"Normal liver, spleen, and kidney dimensions in neonates, infants, and children: evaluation with sonography.","volume":"171","author":"Konus","year":"1998","journal-title":"Am J Roentgenol"},{"key":"R50-1-20210128","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1148\/radiol.2311020963","article-title":"Spleen length in childhood with US: normal values based on age, sex, and somatometric parameters.","volume":"231","author":"Megremis","year":"2004","journal-title":"Radiology"},{"key":"R51-1-20210128","doi-asserted-by":"crossref","first-page":"119","DOI":"10.2214\/ajr.157.1.2048509","article-title":"Normal splenic size in infants and children; sonographic measurements.","volume":"157","author":"Rosenberg","year":"1991","journal-title":"Am J Roentgenol"},{"key":"R52-1-20210128","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1002\/(SICI)1097-0096(199902)27:2<71::AID-JCU4>3.0.CO;2-U","article-title":"Sonographic measurement of splenic length: correlation with measurement at autopsy.","volume":"27","author":"Loftus","year":"1999","journal-title":"J Clin Ultrasound"},{"key":"R53-1-20210128","first-page":"1","article-title":"Ultrasonographic study on the growth and dimensions of healthy children and adult organs.","volume":"105","author":"Capaccioli","year":"2000","journal-title":"Int J Anat Embryol"},{"key":"R54-1-20210128","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1148\/97.3.589","article-title":"Normal spleen size.","volume":"97","author":"DeLand","year":"1970","journal-title":"Radiology"},{"key":"R55-1-20210128","doi-asserted-by":"crossref","first-page":"45","DOI":"10.2214\/ajr.184.1.01840045","article-title":"Sonographic evaluation of spleen size in tall healthy athletes.","volume":"184","author":"Spielmann","year":"2005","journal-title":"Am J Roentgenol"},{"key":"R56-1-20210128","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1136\/bjsm.2005.022376","article-title":"Ultrasound assessment of spleen size in collegiate athletes.","volume":"40","author":"Hosey","year":"2006","journal-title":"Br J Sports Med"},{"key":"R57-1-20210128","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1093\/infdis\/174.2.324","article-title":"Acyclovir and prednisolone treatment of acute infectious mononucleosis: a multicenter, double-blind, placebo-controlled study.","volume":"174","author":"Tynell","year":"1996","journal-title":"J Infect Dis"},{"key":"R58-1-20210128","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1093\/infdis\/164.4.788","article-title":"Lack of effect of peroral acyclovir for the treatment of acute infectious mononucleosis.","volume":"164","author":"van der Horst","year":"1991","journal-title":"J Infect Dis"},{"key":"R59-1-20210128","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1080\/00365549950164409","article-title":"Acyclovir for treatment of infectious mononucleosis: a meta-analysis.","volume":"31","author":"Torre","year":"1999","journal-title":"Scand J Infect Dis"},{"key":"R60-1-20210128","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1001\/archinte.1986.00360140167024","article-title":"Corticosteroid therapy in Epstein-Barr virus infection.","volume":"146","author":"Brandfonbrener","year":"1986","journal-title":"Arch Intern Med"},{"key":"R61-1-20210128","doi-asserted-by":"crossref","first-page":"900","DOI":"10.1001\/archotol.131.10.900","article-title":"Infectious mononucleosis and corticosteroids: management practices and outcomes.","volume":"131","author":"Thompson","year":"2005","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"R62-1-20210128","first-page":"CD004402","article-title":"Steroids for symptom control in infectious mononucleosis.","volume":"3","author":"Candy","year":"2006","journal-title":"Cochrane Database Syst Rev"},{"key":"R64-1-20210128","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1097\/00005373-199608000-00003","article-title":"Rupture of the pathologic spleen: is there a role for nonoperative therapy?","volume":"41","author":"Guth","year":"1996","journal-title":"J Trauma"},{"key":"R65-1-20210128","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1002\/jmv.10494","article-title":"Increased susceptibility to HIV-1 of peripheral blood lymphocytes in acute infection with Epstein-Barr virus.","volume":"71","author":"Moriuchi","year":"2003","journal-title":"J Med Virol"},{"key":"R66-1-20210128","doi-asserted-by":"crossref","first-page":"1097","DOI":"10.1182\/blood.V65.5.1097.1097","article-title":"Epstein-Barr virus associated hemophagocytic syndrome: virological and immunopathological studies.","volume":"65","author":"Sullivan","year":"1985","journal-title":"Blood"},{"key":"R67-1-20210128","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1532\/IJH97.05020","article-title":"X-linked lymphoproliferative disease in an adult.","volume":"82","author":"Hoshino","year":"2005","journal-title":"Int J Hemat"},{"key":"R68-1-20210128","doi-asserted-by":"crossref","first-page":"137","DOI":"10.2174\/1568008033340270","article-title":"The evolving therapeutic approaches for Epstein Barr virus infection in immunocompetent and immunocompromised individuals.","volume":"3","author":"Okano","year":"2003","journal-title":"Curr Drug Targets Immune Endocr Metabol Dis"},{"key":"R69-1-20210128","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.csm.2005.03.003","article-title":"Training room management of medical conditions: infectious diseases.","volume":"24","author":"Hosey","year":"2005","journal-title":"Clin Sports Med"},{"key":"R70-1-20210128","doi-asserted-by":"crossref","first-page":"27","DOI":"10.3810\/psm.2002.01.137","article-title":"Infectious mononucleosis. Ensuring a safe return to sport.","volume":"30","author":"MacKnight","year":"2002","journal-title":"Phys Sportsmed"},{"key":"R71-1-20210128","doi-asserted-by":"crossref","first-page":"199","DOI":"10.2519\/jospt.1986.8.4.199","article-title":"Aerobic capacity after contracting infectious mononucleosis.","volume":"8","author":"Welch","year":"1986","journal-title":"Orthop Sports Phys Ther"}],"container-title":["Clinical Journal of Sport Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.lww.com\/00042752-200807000-00001","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,10]],"date-time":"2021-04-10T06:32:52Z","timestamp":1618036372000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00042752-200807000-00001"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7]]},"references-count":59,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1097\/jsm.0b013e31817e34f8","relation":{},"ISSN":["1050-642X"],"issn-type":[{"value":"1050-642X","type":"print"}],"subject":[],"published":{"date-parts":[[2008,7]]}}}