{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T07:08:22Z","timestamp":1789715302174,"version":"4.0.1"},"reference-count":26,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,1,1]],"date-time":"2012-01-01T00:00:00Z","timestamp":1325376000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,12,2]],"date-time":"2015-12-02T00:00:00Z","timestamp":1449014400000},"content-version":"vor","delay-in-days":1431,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Thoracic Oncology"],"published-print":{"date-parts":[[2012,1]]},"DOI":"10.1097\/jto.0b013e31822f6544","type":"journal-article","created":{"date-parts":[[2011,10,19]],"date-time":"2011-10-19T08:23:39Z","timestamp":1319012619000},"page":"243-248","source":"Crossref","is-referenced-by-count":8,"title":["Sustained Expression of Steroid Receptor Coactivator SRC-2\/TIF-2 is Associated with Better Prognosis in Malignant Pleural Mesothelioma"],"prefix":"10.1016","volume":"7","author":[{"given":"Cormac J.","family":"Jennings","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony","family":"O'Grady","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Cummins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruno","family":"Murer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mazen","family":"Al-Alawi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen F.","family":"Madden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano","family":"Mutti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian J.","family":"Harvey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Warren","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elaine W.","family":"Kay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1097\/JTO.0b013e31822f6544_bib1","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/j.1440-1843.2005.00714.x","article-title":"Advances in the diagnosis, evaluation, and management of malignant pleural mesothelioma","volume":"10","author":"Sterman","year":"2005","journal-title":"Respirology"},{"key":"10.1097\/JTO.0b013e31822f6544_bib2","doi-asserted-by":"crossref","first-page":"14128","DOI":"10.1073\/pnas.0604544103","article-title":"Crocidolite asbestos and SV40 are cocarcinogens in human mesothelial cells and in causing mesothelioma in hamsters","volume":"103","author":"Kroczynska","year":"2006","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1097\/JTO.0b013e31822f6544_bib3","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/nrc2068","article-title":"A mesothelioma epidemic in Cappadocia: scientific developments and unexpected social outcomes","volume":"7","author":"Carbone","year":"2007","journal-title":"Nat Rev Cancer"},{"key":"10.1097\/JTO.0b013e31822f6544_bib4","doi-asserted-by":"crossref","first-page":"1041","DOI":"10.1016\/j.hoc.2005.09.009","article-title":"Prognostic factors for mesothelioma","volume":"19","author":"Steele","year":"2005","journal-title":"Hematol Oncol Clin North Am"},{"key":"10.1097\/JTO.0b013e31822f6544_bib5","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1097\/JTO.0b013e31815608d9","article-title":"Prognostic factors in the treatment of malignant pleural mesothelioma at a large tertiary referral center","volume":"2","author":"Flores","year":"2007","journal-title":"J Thorac Oncol"},{"key":"10.1097\/JTO.0b013e31822f6544_bib6","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/S0022-5223(98)70274-0","article-title":"Preoperative tumor volume is associated with outcome in malignant pleural mesothelioma","volume":"115","author":"Pass","year":"1998","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1097\/JTO.0b013e31822f6544_bib7","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1136\/thorax.55.9.731","article-title":"Prognostic factors for malignant mesothelioma in 142 patients: validation of CALGB and EORTC prognostic scoring systems","volume":"55","author":"Edwards","year":"2000","journal-title":"Thorax"},{"key":"10.1097\/JTO.0b013e31822f6544_bib8","doi-asserted-by":"crossref","first-page":"4598","DOI":"10.1158\/0008-5472.CAN-08-4523","article-title":"Estrogen receptor-beta affects the prognosis of human malignant mesothelioma","volume":"69","author":"Pinton","year":"2009","journal-title":"Cancer Res"},{"key":"10.1097\/JTO.0b013e31822f6544_bib9","first-page":"321","article-title":"Nuclear receptor coregulators: cellular and molecular biology","volume":"20","author":"McKenna","year":"1999","journal-title":"Endocr Rev"},{"key":"10.1097\/JTO.0b013e31822f6544_bib10","doi-asserted-by":"crossref","first-page":"1354","DOI":"10.1126\/science.270.5240.1354","article-title":"Sequence and characterization of a coactivator for the steroid hormone receptor superfamily","volume":"270","author":"Onate","year":"1995","journal-title":"Science"},{"key":"10.1097\/JTO.0b013e31822f6544_bib11","doi-asserted-by":"crossref","first-page":"3667","DOI":"10.1002\/j.1460-2075.1996.tb00736.x","article-title":"TIF2, a 160 kDa transcriptional mediator for the ligand-dependent activation function AF-2 of nuclear receptors","volume":"15","author":"Voegel","year":"1996","journal-title":"EMBO J"},{"key":"10.1097\/JTO.0b013e31822f6544_bib12","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1126\/science.277.5328.965","article-title":"AIB1, a steroid receptor coactivator amplified in breast and ovarian cancer","volume":"277","author":"Anzick","year":"1997","journal-title":"Science"},{"key":"10.1097\/JTO.0b013e31822f6544_bib13","doi-asserted-by":"crossref","first-page":"6992","DOI":"10.1200\/JCO.2005.01.2906","article-title":"Predictors of prostate cancer-specific mortality after radical prostatectomy or radiation therapy","volume":"23","author":"Zhou","year":"2005","journal-title":"J Clin Oncol"},{"key":"10.1097\/JTO.0b013e31822f6544_bib14","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1016\/j.ccr.2004.06.027","article-title":"High tumor incidence and activation of the PI3K\/AKT pathway in transgenic mice define AIB1 as an oncogene","volume":"6","author":"Torres-Arzayus","year":"2004","journal-title":"Cancer Cell"},{"key":"10.1097\/JTO.0b013e31822f6544_bib15","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1677\/erc.1.00800","article-title":"Loss of ERbeta expression as a common step in estrogen-dependent tumor progression","volume":"11","author":"Bardin","year":"2004","journal-title":"Endocr Relat Cancer"},{"key":"10.1097\/JTO.0b013e31822f6544_bib16","first-page":"245","article-title":"Selective loss of estrogen receptor beta in malignant human colon","volume":"60","author":"Foley","year":"2000","journal-title":"Cancer Res"},{"key":"10.1097\/JTO.0b013e31822f6544_bib17","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1007\/s00384-009-0647-9","article-title":"Estrogen receptor alpha\/beta, AIB1, and TIF2 in colorectal carcinogenesis: do coregulators have prognostic significance?","volume":"24","author":"Grivas","year":"2009","journal-title":"Int J Colorectal Dis"},{"key":"10.1097\/JTO.0b013e31822f6544_bib18","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1093\/jnci\/85.3.200","article-title":"Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer","volume":"85","author":"Allred","year":"1993","journal-title":"J Natl Cancer Inst"},{"key":"10.1097\/JTO.0b013e31822f6544_bib19","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1093\/biomet\/69.3.553","article-title":"A class of rank procedures for censored survival data","volume":"69","author":"Harrington","year":"1982","journal-title":"Biometrika"},{"key":"10.1097\/JTO.0b013e31822f6544_bib20","doi-asserted-by":"crossref","first-page":"1100","DOI":"10.1214\/aos\/1176345976","article-title":"Cox's regression model for counting processes, a large sample study","volume":"10","author":"Andersen","year":"1982","journal-title":"Ann Stat"},{"key":"10.1097\/JTO.0b013e31822f6544_bib21","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1002\/(SICI)1096-9896(199802)184:2<153::AID-PATH993>3.0.CO;2-W","article-title":"Expression of oestrogen receptor and oestrogen-inducible genes pS2 and ERD5 in large bowel mucosa and cancer","volume":"184","author":"Singh","year":"1998","journal-title":"J Pathol"},{"key":"10.1097\/JTO.0b013e31822f6544_bib22","doi-asserted-by":"crossref","first-page":"3021","DOI":"10.1038\/sj.onc.1210964","article-title":"Ets-2 and p160 proteins collaborate to regulate c-Myc in endocrine resistant breast cancer","volume":"27","author":"Al-azawi","year":"2008","journal-title":"Oncogene"},{"key":"10.1097\/JTO.0b013e31822f6544_bib23","doi-asserted-by":"crossref","first-page":"e14110","DOI":"10.1371\/journal.pone.0014110","article-title":"Estrogen receptor beta exerts tumor repressive functions in human malignant pleural mesothelioma via EGFR inactivation and affects response to gefitinib","volume":"5","author":"Pinton","year":"2010","journal-title":"PLoS One"},{"key":"10.1097\/JTO.0b013e31822f6544_bib24","doi-asserted-by":"crossref","first-page":"423","DOI":"10.1158\/0008-5472.CAN-03-2446","article-title":"Estrogen receptor beta inhibits human breast cancer cell proliferation and tumor formation by causing a G2 cell cycle arrest","volume":"64","author":"Paruthiyil","year":"2004","journal-title":"Cancer Res"},{"key":"10.1097\/JTO.0b013e31822f6544_bib25","doi-asserted-by":"crossref","first-page":"1566","DOI":"10.1073\/pnas.0308319100","article-title":"Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D","volume":"101","author":"Strom","year":"2004","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1097\/JTO.0b013e31822f6544_bib26","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.febslet.2004.04.025","article-title":"Expression of estrogen receptor beta in prostate carcinoma cells inhibits invasion and proliferation and triggers apoptosis","volume":"566","author":"Cheng","year":"2004","journal-title":"FEBS Lett"}],"container-title":["Journal of Thoracic Oncology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1556086415317846?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1556086415317846?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,7,13]],"date-time":"2022-07-13T20:38:33Z","timestamp":1657744713000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1556086415317846"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,1]]},"references-count":26,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,1]]}},"alternative-id":["S1556086415317846"],"URL":"https:\/\/doi.org\/10.1097\/jto.0b013e31822f6544","relation":{},"ISSN":["1556-0864"],"issn-type":[{"value":"1556-0864","type":"print"}],"subject":[],"published":{"date-parts":[[2012,1]]}}}