{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T22:39:29Z","timestamp":1792276769294,"version":"4.4.0"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,10]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Flexible bronchoscopy (FB) is a common modality for diagnostic sampling within the thorax. It is utilized often in the elderly population, but there is limited data on the safety and utility of the procedure in the very elderly.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>FBs performed outside the intensive care unit in the San Antonio Military Health System on patients 85 years and older were reviewed. Outcomes including indications, complications, diagnostic yield, and final diagnosis were compared with a control group consisting of patients\u2019 ages of 65 to 79 years old.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>Seventy-three bronchoscopies were performed in each group. The mean age of the older group was 87.1\u00b12.6 years, and had a higher American Society of Anesthesiology (ASA) class than the younger group (<jats:italic toggle=\"yes\">P<\/jats:italic>=0.03). There were no significant differences in the indications for bronchoscopy (<jats:italic toggle=\"yes\">P<\/jats:italic>&gt;0.05), sampling performed (<jats:italic toggle=\"yes\">P<\/jats:italic>&gt;0.05), complication rates (<jats:italic toggle=\"yes\">P<\/jats:italic>&gt;0.05), diagnostic yield (<jats:italic toggle=\"yes\">P<\/jats:italic>&gt;0.05), or final diagnoses (<jats:italic toggle=\"yes\">P<\/jats:italic>&gt;0.05). Similar proportions of each group with a malignancy diagnosis received some form of therapy (<jats:italic toggle=\"yes\">P<\/jats:italic>&gt;0.05), although fewer of the older group underwent surgery (<jats:italic toggle=\"yes\">P<\/jats:italic>=0.03). Analysis of the cohort demonstrated that ASA class 3 to 4 was associated with increased rate of complications and use of anesthesia compared with lower ASA class (<jats:italic toggle=\"yes\">P<\/jats:italic>&lt;0.02).<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>FB in the elderly demonstrated no differences in procedural complications, diagnostic yield, and utility of the procedure for an underlying diagnosis. This study suggests bronchoscopy is as safe and useful in the very elderly as a population of the age of 65 to 79.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/lbr.0000000000000511","type":"journal-article","created":{"date-parts":[[2018,5,15]],"date-time":"2018-05-15T22:38:34Z","timestamp":1526423914000},"page":"300-304","source":"Crossref","is-referenced-by-count":17,"title":["The Safety and Utility of Fiberoptic Bronchoscopy in the Very Elderly"],"prefix":"10.1097","volume":"25","author":[{"given":"Cameron W.","family":"McLaughlin","sequence":"first","affiliation":[{"name":"Pulmonary\/Critical Care Service, Department of Medicine, San Antonio Military Medical Center, JBSA Fort Sam Houston, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Skabelund","sequence":"additional","affiliation":[{"name":"Pulmonary\/Critical Care Service, Department of Medicine, San Antonio Military Medical Center, JBSA Fort Sam Houston, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ellis R.","family":"Easterling","sequence":"additional","affiliation":[{"name":"Internal Medicine Service, Department of Medicine, Keesler Medical Center, Keesler Air Force Base, MS"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Morris","sequence":"additional","affiliation":[{"name":"Pulmonary\/Critical Care Service, Department of Medicine, San Antonio Military Medical Center, JBSA Fort Sam Houston, TX"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20230927","doi-asserted-by":"crossref","first-page":"33324","DOI":"10.3402\/ecrj.v3.33324","article-title":"Complications and discomfort of bronchoscopy: a systematic review","volume":"3","author":"Leiten","year":"2016","journal-title":"Eur Clin Respir J"},{"key":"R2-20230927","first-page":"115","article-title":"The elderly tolerate fiberoptic bronchoscopy as well as younger patients","volume":"4","author":"Costello","year":"1997","journal-title":"J Bronchology Interven Pulmon"},{"key":"R3-20230927","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1093\/ageing\/10.2.127","article-title":"Safety, usefulness and acceptability of fibreoptic bronchoscopy in the elderly","volume":"10","author":"Macfarlane","year":"1981","journal-title":"Age Ageing"},{"key":"R4-20230927","first-page":"546","article-title":"Flexible fiberoptic bronchoscopy in the elderly","volume":"84","author":"Brandstetter","year":"1984","journal-title":"N Y State J Med"},{"key":"R5-20230927","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1093\/ageing\/16.4.229","article-title":"Fibreoptic bronchoscopy in the elderly","volume":"16","author":"O\u2019Hickey","year":"1987","journal-title":"Age Ageing"},{"key":"R6-20230927","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/0007-0971(88)90071-X","article-title":"Fibreoptic bronchoscopy in the elderly: 4 years\u2019 experience","volume":"82","author":"Knox","year":"1988","journal-title":"Br J Dis Chest"},{"key":"R7-20230927","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1046\/j.1365-2389.2003.51303.x","article-title":"The relationship between age and process of care and patient tolerance of bronchoscopy","volume":"51","author":"Hehn","year":"2003","journal-title":"J Am Geriatr Soc"},{"key":"R8-20230927","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1097\/00128594-200304000-00005","article-title":"Bronchoscopic procedures in octogenarians: a case-control analysis","volume":"10","author":"Allan","year":"2003","journal-title":"J Bronchology"},{"key":"R9-20230927","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1111\/jgs.13999","article-title":"Complications of fiberoptic bronchoscopy in very elderly adults","volume":"64","author":"Haga","year":"2016","journal-title":"J Am Geriatr Soc"},{"key":"R10-20230927","doi-asserted-by":"crossref","first-page":"1803","DOI":"10.1111\/jgs.12996","article-title":"Indications and complications associated with fiberoptic bronchoscopy in very elderly adults","volume":"62","author":"Haga","year":"2014","journal-title":"J Am Geriatr Soc"},{"key":"R11-20230927","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1093\/ageing\/afn127","article-title":"Bronchoscopy in octogenarians","volume":"37","author":"Rokach","year":"2008","journal-title":"Age Ageing"},{"key":"R12-20230927","doi-asserted-by":"crossref","first-page":"2331","DOI":"10.1001\/jama.1993.03500180015006","article-title":"Demographers ponder the aging of the aged and await unprecedented looming elder boom","volume":"269","author":"Randall","year":"1993","journal-title":"JAMA"},{"key":"R13-20230927","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1016\/S0140-6736(14)60569-9","article-title":"Causes of international increases in older age life expectancy","volume":"385","author":"Mathers","year":"2015","journal-title":"Lancet"},{"key":"R14-20230927","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1378\/chest.114.6.1704","article-title":"Geriatric respiratory medicine","volume":"114","author":"Chan","year":"1998","journal-title":"Chest"},{"key":"R15-20230927","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1093\/ageing\/afp180","article-title":"Dispelling myths regarding the safety of \u201cbronchoscopy in octogenerians\u201d","volume":"38","author":"Chotirmall","year":"2009","journal-title":"Age Ageing"}],"container-title":["Journal of Bronchology &amp; Interventional Pulmonology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/01436970-201810000-00010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,27]],"date-time":"2023-09-27T04:40:04Z","timestamp":1695789604000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01436970-201810000-00010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018]]}},"URL":"https:\/\/doi.org\/10.1097\/lbr.0000000000000511","relation":{},"ISSN":["1944-6586"],"issn-type":[{"value":"1944-6586","type":"print"}],"subject":[],"published":{"date-parts":[[2018,10]]}}}