{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T11:19:08Z","timestamp":1785842348956,"version":"3.56.0"},"reference-count":71,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,4]]},"DOI":"10.1097\/lgt.0b013e31825f4b4f","type":"journal-article","created":{"date-parts":[[2013,1,23]],"date-time":"2013-01-23T11:54:11Z","timestamp":1358942051000},"page":"167-174","source":"Crossref","is-referenced-by-count":32,"title":["Extramammary Paget Disease"],"prefix":"10.1097","volume":"17","author":[{"given":"Deana","family":"Funaro","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Krasny","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christina","family":"Lam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delphine","family":"Desy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe","family":"Sauthier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danielle","family":"Bouffard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-12-20210126","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/0090-8258(90)90269-Q","article-title":"SC Rubin, WB Jones, WJ Hoskins, JL Lewis. Pagets disease of the vulva.","volume":"39","author":"Curtin","year":"1990","journal-title":"Gynecol Oncol"},{"key":"R2-12-20210126","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1111\/j.1471-0528.2004.00438.x","article-title":"Extramammary Pagets disease.","volume":"112","author":"Shepherd","year":"2005","journal-title":"BJOG"},{"key":"R3-12-20210126","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1111\/j.1468-3083.2007.02154.x","article-title":"Mammary and extramammary Pagets disease.","volume":"21","author":"Kanitakis","year":"2007","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"R4-12-20210126","doi-asserted-by":"crossref","first-page":"742","DOI":"10.1136\/jcp.53.10.742","article-title":"Mammary and extramammary Pagets disease.","volume":"53","author":"Lloyd","year":"2000","journal-title":"J Clin Pathol"},{"key":"R5-12-20210126","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/S0190-9622(85)70254-X","article-title":"Extramammary Pagets disease: prognosis and relationship to internal malignancy.","volume":"13","author":"Chanda","year":"1985","journal-title":"J Am Acad Dermatol"},{"key":"R6-12-20210126","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/0090-8258(90)90016-E","article-title":"Vulvar Pagets disease: the need to exclude an invasive lesion.","volume":"38","author":"Feuer","year":"1990","journal-title":"Gynecol Oncol"},{"key":"R7-12-20210126","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1006\/gyno.1995.1010","article-title":"A clinicopathologic study of 30 patients with Pagets disease of the vulva.","volume":"56","author":"Kodama","year":"1995","journal-title":"Gynecol Oncol"},{"key":"R8-12-20210126","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1097\/00000478-199802000-00004","article-title":"Perianal Pagets disease: a histologic and immunohistochemical study of 11 cases with and without associated rectal adenocarcinoma.","volume":"22","author":"Goldblum","year":"1998","journal-title":"Am J Surg Pathol"},{"key":"R9-12-20210126","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1006\/gyno.2000.5741","article-title":".Pagets disease of the vulva: pathology, pattern of involvement and prognosis.","volume":"77","author":"Parker","year":"2000","journal-title":"Gynecol Oncol"},{"key":"R10-12-20210126","doi-asserted-by":"crossref","first-page":"1178","DOI":"10.1097\/00000478-199710000-00008","article-title":"Vulvar Pagets disease: a clinicopathologic and immunohistochemical study of 19 cases.","volume":"21","author":"Goldblum","year":"1997","journal-title":"Am J Surg Pathol"},{"key":"R11-12-20210126","first-page":"313","article-title":"Extramammary Pagets disease: treatment, prognostic factors and outcome in 76 patients.","volume":"158","author":"Hatta","year":"2008","journal-title":"Br J Dermatol"},{"key":"R13-12-20210126","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1046\/j.1365-2133.2000.03242.x","article-title":"The Roswell Park Cancer Institute experience with extramammary Pagets disease.","volume":"142","author":"Zollo","year":"2000","journal-title":"Br J Dermatol"},{"issue":"suppl 1","key":"R14-12-20210126","first-page":"74","article-title":"Pagets disease of the vulva: advantages of demolitive surgery.","volume":"13","author":"Garzetti","year":"1992","journal-title":"Eur J Gynaecol Oncol"},{"key":"R15-12-20210126","first-page":"611","article-title":"Pagets disease of the vulvaa review of our experience.","volume":"27","author":"Petkovic","year":"2006","journal-title":"Eur J Gynaecol Oncol"},{"key":"R16-12-20210126","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1016\/S0301-2115(01)00394-3","article-title":"Pagets disease of the vulva: results of different conservative treatments.","volume":"99","author":"Louis-Sylvestre","year":"2001","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"R17-12-20210126","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1080\/01443610410001645370","article-title":"The management of Pagets disease of the vulva.","volume":"24","author":"Maclean","year":"2004","journal-title":"J Obstet Gynecol"},{"key":"R18-12-20210126","first-page":"203","article-title":". Vulvar Pagets disease. Clinico-pathologic review of the literature.","volume":"52","author":"Preti","year":"2000","journal-title":"Minerva Ginecol"},{"key":"R19-12-20210126","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/0090-8258(89)90541-6","article-title":"Conservative management of extramammary Pagets disease of the vulva.","volume":"33","author":"Bergen","year":"1989","journal-title":"Gynecol Oncol"},{"key":"R21-12-20210126","first-page":"522","article-title":"Paget disease of the vulva. 36 cases.","volume":"120","author":"Molinie","year":"1993","journal-title":"Ann Dermatol Venereol"},{"key":"R22-12-20210126","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1016\/j.ygyno.2006.09.017","article-title":"The outcomes of patients with positive margins after excision for intraepithelial Pagets disease of the vulva.","volume":"104","author":"Black","year":"2007","journal-title":"Gynecol Oncol"},{"key":"R23-12-20210126","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1001\/archderm.1979.04010060014018","article-title":"Microscopically controlled surgery for extramammary Pagets disease.","volume":"115","author":"Mohs","year":"1979","journal-title":"Arch Dermatol"},{"key":"R24-12-20210126","first-page":"723","article-title":". Comparison of Mohs micrographic surgery and wide local excision for extramammary Pagets disease.","volume":"29","author":"OConnor","year":"2003","journal-title":"Dermatol Surg"},{"key":"R25-12-20210126","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1002\/1097-0142(19910215)67:4<933::AID-CNCR2820670413>3.0.CO;2-3","article-title":"Surgical treatment of extramammary Pagets disease. A report of six cases and a reexamination of Mohs micrographic surgery compared with conventional surgical excision.","volume":"67","author":"Coldiron","year":"1991","journal-title":"Cancer"},{"key":"R26-12-20210126","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.jaad.2004.07.004","article-title":"Extramammary Pagets disease: surgical treatment with Mohs micrographic surgery.","volume":"51","author":"Hendi","year":"2004","journal-title":"J Am Acad Dermatol"},{"key":"R27-12-20210126","first-page":"333","article-title":"Mohs micrographic surgery in the treatment of rare aggressive cutaneous tumours: the Geisinger experience.","volume":"33","author":"Thomas","year":"2007","journal-title":"Dermatol Surg"},{"key":"R29-12-20210126","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1006\/gyno.1995.1044","article-title":"Extramammary Pagets disease of the vulva.","volume":"56","author":"Fishman","year":"1995","journal-title":"Gynecol Oncol"},{"key":"R30-12-20210126","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1002\/1097-0142(19800801)46:3<590::AID-CNCR2820460327>3.0.CO;2-Q","article-title":"Vulvar Pagets disease: a topographic study.","volume":"46","author":"Gunn","year":"1980","journal-title":"Cancer"},{"key":"R31-12-20210126","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1089\/gyn.1992.8.21","article-title":"Laser ablation of recurrent Pagets disease of vulva and perineum.","volume":"8","author":"Valentine","year":"1992","journal-title":"J Gynecol Surg"},{"key":"R32-12-20210126","first-page":"269","article-title":"Nd: YAG laser treatment of extramammary Pagets disease of the penis and scrotum.","volume":"99","author":"Weese","year":"1993","journal-title":"J Urol (Paris)"},{"key":"R33-12-20210126","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0090-8258(91)90059-E","article-title":"Pagets disease of the vulva treated by combined surgery and laser.","volume":"43","author":"Ewing","year":"1991","journal-title":"Gynecol Oncol"},{"key":"R34-12-20210126","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1046\/j.1464-410x.2001.02326.x","article-title":"Failure of carbon dioxide laser treatment in three patients with penoscrotal extramammary Pagets disease.","volume":"88","author":"Choi","year":"2001","journal-title":"BJU International"},{"key":"R35-12-20210126","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1046\/j.1365-2133.2002.04801.x","article-title":"Photodynamic therapy for the treatment of extramammary Pagets disease.","volume":"146","author":"Shieh","year":"2002","journal-title":"Br J Dermatol"},{"key":"R36-12-20210126","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1046\/j.1365-2133.1999.02991.x","article-title":"Photodynamic therapy for inoperable vulvar Pagets disease using delta-aminolaevulinic acid: successful management of a large skin lesion.","volume":"141","author":"Henta","year":"1999","journal-title":"Br J Dermatol"},{"key":"R37-12-20210126","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1111\/j.1346-8138.2005.tb00724.x","article-title":". 5-Aminolevulinic acid-based photodynamic therapy for the treatment of two patients with extramammary Pagets disease.","volume":"32","author":"Mikasa","year":"2005","journal-title":"J Dermatol"},{"key":"R38-12-20210126","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1007\/BF02237193","article-title":"Photodynamic therapy for residual neoplasms of the perianal skin.","volume":"43","author":"Runfola","year":"2000","journal-title":"Dis Colon Rectum"},{"key":"R39-12-20210126","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1007\/s10103-009-0653-8","article-title":"Treatment of perianal Pagets disease using photodynamic therapy with assistance of fluorescence examination: case report.","volume":"24","author":"Li","year":"2009","journal-title":"Lasers Med Sci"},{"key":"R40-12-20210126","first-page":"161","article-title":"Extramammary Pagets disease.","volume":"118","author":"Haberman","year":"1978","journal-title":"Can Med Assoc J"},{"key":"R41-12-20210126","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1001\/archderm.1971.04000210090018","article-title":"Triple extramammary Pagets disease.","volume":"104","author":"Kawatsu","year":"1971","journal-title":"Arch Dermatol"},{"key":"R42-12-20210126","first-page":"331","article-title":"Spontaneous apparent clinical resolution with histologic persistence of a case of extramammary Pagets disease: response to topical 5-FU.","volume":"65","author":"Del Castillo","year":"2000","journal-title":"Cutis"},{"key":"R43-12-20210126","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0190-9622(87)70236-9","article-title":"Role of preoperative topical 5-FU in preparation for Mohs micrographic surgery of extramammary Pagets disease.","volume":"17","author":"Eliezri","year":"1987","journal-title":"J Am Acad Dermatol"},{"key":"R44-12-20210126","doi-asserted-by":"crossref","first-page":"S229","DOI":"10.1067\/mjd.2002.126584","article-title":"Treatment of primary limited cutaneous extramammary Pagets disease with topical imiquimod monotherapy: two case reports.","volume":"47","author":"Zampogna","year":"2002","journal-title":"J Am Acad Dermatol"},{"key":"R46-12-20210126","first-page":"73","article-title":"Successful treatment of extramammary Pagets disease with imiquimod.","volume":"2","author":"Qian","year":"2003","journal-title":"J Drugs Dermatol"},{"key":"R47-12-20210126","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1080\/09546630600788877","article-title":"Treatment of mammary and extramammary Pagets skin disease with topical imiquimod.","volume":"17","author":"Mirer","year":"2006","journal-title":"J Dermatolog Treat"},{"key":"R48-12-20210126","doi-asserted-by":"crossref","first-page":"22","DOI":"10.5070\/D36CD2F48F","article-title":"Treatment of limited extent extramammary Pagets disease with 5 percent imiquimod cream.","volume":"12","author":"Badgwell","year":"2006","journal-title":"Dermatol Online J"},{"key":"R49-12-20210126","first-page":"CS75","article-title":". A therapeutic approach to perianal extramammary Pagets disease: topical imiquimod can be useful to prevent or defer surgery.","volume":"13","author":"Vereecken","year":"2007","journal-title":"Med Sci Monit"},{"key":"R50-12-20210126","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1097\/LGT.0b013e31815a58a5","article-title":"Complete resolution of Paget disease of the vulva with imiquimod cream.","volume":"12","author":"Hatch","year":"2008","journal-title":"J Lower Gen Tract Dis"},{"key":"R51-12-20210126","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1067\/S0190-9622(03)02107-8","article-title":"Successful treatment of recurrent extramammary Pagets disease of the vulva with topical imiquimod 5 cream.","volume":"49","author":"Wang","year":"2003","journal-title":"J Am Acad Dermatol"},{"key":"R52-12-20210126","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1002\/1097-0142(197801)41:1<10::AID-CNCR2820410103>3.0.CO;2-G","article-title":". Treatment of recurrent Pagets disease of the vulva with topical bleomycin.","volume":"41","author":"Watring","year":"1978","journal-title":"Cancer"},{"key":"R53-12-20210126","doi-asserted-by":"crossref","first-page":"293","DOI":"10.3109\/07357908809080652","article-title":"Extramammary Pagets disease: an annotated review.","volume":"6","author":"Balducci","year":"1988","journal-title":"Cancer Invest"},{"key":"R54-12-20210126","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/S0936-6555(05)81030-1","article-title":"Radiotherapy: an effective treatment for extramammary Pagets disease.","volume":"3","author":"Brierley","year":"1991","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"R55-12-20210126","first-page":"587","article-title":"Radiotherapy for genital extramammary Pagets disease in situ.","volume":"27","author":"Moreno-Arias","year":"2001","journal-title":"Dermatol Surg"},{"key":"R56-12-20210126","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1046\/j.1440-1673.2001.01039.x","article-title":"Extramammary Pagets disease: role of radiation therapy.","volume":"46","author":"Guerrieri","year":"2002","journal-title":"Australas Radiol"},{"key":"R57-12-20210126","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1111\/j.1365-2133.1995.tb16957.x","article-title":"Treatment of extramammary Pagets disease by radiotherapy.","volume":"132","author":"Burrows","year":"1995","journal-title":"Br J Dermatol"},{"key":"R58-12-20210126","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1046\/j.1365-2230.2003.01301.x","article-title":"Extramammary Pagets disease: outcome of radiotherapy with curative intent.","volume":"28","author":"Luk","year":"2003","journal-title":"Clin Exp Dermatol"},{"key":"R59-12-20210126","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/0360-3016(92)91024-H","article-title":"Extramammary Pagets disease of the perineal skin: role of radiotherapy.","volume":"24","author":"Besa","year":"1992","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"R60-12-20210126","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1111\/j.1365-2230.2007.02425.x","article-title":"Radiotherapy for extramammary Pagets disease: histopathological findings after radiotherapy.","volume":"32","author":"Yanagi","year":"2007","journal-title":"Clin Exp Dermatol"},{"key":"R61-12-20210126","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/S0936-6555(05)80016-0","article-title":"Perineal Pagets disease: effective treatment with fractionated high dose rate brachytherapy.","volume":"7","author":"Kwan","year":"1995","journal-title":"Clin Oncol (R Coll Radiol)"},{"key":"R63-12-20210126","doi-asserted-by":"crossref","first-page":"81","DOI":"10.3747\/co.v16i5.374","article-title":"Response to 5-FU in metastatic extramammary Paget disease of the scrotum presenting as pancytopenia and back pain.","volume":"16","author":"Beleznay","year":"2009","journal-title":"Curr Oncol"},{"key":"R64-12-20210126","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1136\/ijgc-00009577-200205000-00011","article-title":"Low-dose mitomycin C, etoposide, and cisplatin for invasive vulvar Pagets disease.","volume":"12","author":"Watanabe","year":"2002","journal-title":"Int J Gynecol Cancer"},{"key":"R65-12-20210126","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1111\/j.1346-8138.1999.tb03477.x","article-title":"A case of metastatic extramammary Pagets disease that responded to combination chemotherapy.","volume":"26","author":"Yamazaki","year":"1999","journal-title":"J Dermatol"},{"key":"R66-12-20210126","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1111\/j.1346-8138.2005.tb00812.x","article-title":".Extramammary Pagets disease carcinoma successfully treated with combination chemotherapy: report of two cases.","volume":"32","author":"Mochitomi","year":"2005","journal-title":"J Dermatol"},{"key":"R67-12-20210126","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/S1072-7515(02)01619-8","article-title":"Prognosis and management of extramammary Pagets disease and the association with secondary malignancies.","volume":"196","author":"Pierie","year":"2003","journal-title":"J Am Coll Surg"},{"key":"R68-12-20210126","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/BF02590848","article-title":"Perianal Pagets disease: report of 7 cases.","volume":"19","author":"Williams","year":"1976","journal-title":"Dis Colon Rectum"},{"key":"R69-12-20210126","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1007\/BF02556169","article-title":"Perianal Pagets disease.","volume":"30","author":"Beck","year":"1987","journal-title":"Dis Colon Rectum"},{"key":"R70-12-20210126","first-page":"359","article-title":"Perianal extramammary Pagets disease.","volume":"167","author":"Berardi","year":"1988","journal-title":"Surg Gynecol Obstet"},{"key":"R71-12-20210126","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/BF00360360","article-title":"Perianal Pagets disease: report of 5 cases.","volume":"7","author":"Goldman","year":"1992","journal-title":"Int J Colorectal Dis"},{"key":"R72-12-20210126","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1007\/BF02303671","article-title":"Long-term outcome of patients with perianal Pagets disease.","volume":"4","author":"Marchesa","year":"1997","journal-title":"Ann Surg Oncol"},{"key":"R73-12-20210126","first-page":"1187","article-title":"Pagets disease of the perianal regionan aggressive disease Dis Colon R","volume":"40","author":"Sarmiento","year":"1997","journal-title":"ectum"},{"key":"R74-12-20210126","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1007\/s10350-004-6618-x","article-title":"Long-term outcome of perianal Pagets disease.","volume":"46","author":"McCarter","year":"2003","journal-title":"Dis Colon Rectum"},{"key":"R75-12-20210126","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1002\/bjs.1800760119","article-title":"Pagets disease of the anus: a clinicopathologic study.","volume":"76","author":"Armitage","year":"1989","journal-title":"Br J Surg"},{"key":"R76-12-20210126","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1111\/j.1463-1318.2004.00630.x","article-title":"Extramammary Pagets disease of the perianal region.","volume":"6","author":"Tulchinsky","year":"2004","journal-title":"Colorectal Dis"}],"container-title":["Journal of Lower Genital Tract Disease"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.lww.com\/00128360-201304000-00012","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,5]],"date-time":"2024-05-05T03:29:41Z","timestamp":1714879781000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00128360-201304000-00012"}},"subtitle":["Epidemiology and Association to Cancer in a Quebec-Based Population"],"short-title":[],"issued":{"date-parts":[[2013,4]]},"references-count":71,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1097\/lgt.0b013e31825f4b4f","relation":{},"ISSN":["1089-2591"],"issn-type":[{"value":"1089-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2013,4]]}}}