{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:41:50Z","timestamp":1787010110676,"version":"build-2736575974"},"reference-count":17,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2010,12,1]],"date-time":"2010-12-01T00:00:00Z","timestamp":1291161600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The American Journal of the Medical Sciences"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1097\/maj.0b013e3181f41168","type":"journal-article","created":{"date-parts":[[2010,9,19]],"date-time":"2010-09-19T14:51:08Z","timestamp":1284907868000},"page":"514-517","source":"Crossref","is-referenced-by-count":28,"title":["Toxic Hepatitis Induced by Gymnema sylvestre, a Natural Remedy for Type 2 Diabetes Mellitus"],"prefix":"10.1016","volume":"340","author":[{"given":"Arthur","family":"Shiyovich","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lior","family":"Nesher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ignacio","family":"Sztarkier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1097\/MAJ.0b013e3181f41168_bb0010","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1517\/14740338.6.6.673","article-title":"Idiosyncratic drug-induced liver injury: an overview","volume":"6","author":"Hussaini","year":"2007","journal-title":"Expert Opin Drug Saf"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0015","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.3748\/wjg.15.2817","article-title":"Drug-induced liver injury: is it somehow foreseeable?","volume":"15","author":"Tarantino","year":"2009","journal-title":"World J Gastroenterol"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0020","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1089\/107555304323062365","article-title":"Role of selected Indian plants in the management of type 2 diabetes: a review","volume":"10","author":"Saxena","year":"2004","journal-title":"J Altern Complement Med"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0025","doi-asserted-by":"crossref","first-page":"1277","DOI":"10.2337\/diacare.26.4.1277","article-title":"Systematic review of herbs and dietary supplements for glycaemic control in diabetes","volume":"26","author":"Yeh","year":"2003","journal-title":"Diabetes Care"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0030","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2337\/diacare.29.01.06.dc05-1448","article-title":"Association between complementary and alternative medicine use, preventive care practices, and use of conventional medical services among adults with diabetes","volume":"29","author":"Garrow","year":"2006","journal-title":"Diabetes Care"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0035","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1089\/acm.2006.6387","article-title":"Gymnema sylvestre for diabetes mellitus: a systematic review","volume":"13","author":"Leach","year":"2007","journal-title":"J Altern Complement Med"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0040","doi-asserted-by":"crossref","first-page":"758","DOI":"10.1111\/j.1365-2125.2008.03264.x","article-title":"Causality assessment in hepatotoxicity by drugs and dietary supplements","volume":"66","author":"Teschke","year":"2008","journal-title":"Br J Clin Pharmacol"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0045","doi-asserted-by":"crossref","first-page":"2669","DOI":"10.3748\/wjg.15.2669","article-title":"Ceftriaxone-induced toxic hepatitis","volume":"15","author":"Peker","year":"2009","journal-title":"World J Gastroenterol"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0050","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1016\/j.jhep.2009.02.021","article-title":"Acute hepatitis caused by a natural lipid-lowering product: when \u201calternative\u201d medicine is no \u201calternative\u201d at all","volume":"50","author":"Grieco","year":"2009","journal-title":"J Hepatol"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0055","series-title":"What is CAM?","author":"National Center for Complementary and Alternative Medicine, National Institute of Health","year":"2010"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0060","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1016\/0378-8741(90)90108-6","article-title":"Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients","volume":"30","author":"Baskaran","year":"1990","journal-title":"J Ethnopharmacol"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0065","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/0378-8741(90)90107-5","article-title":"Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus","volume":"30","author":"Shanmugasundaram","year":"1990","journal-title":"J Ethnopharmacol"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0070","first-page":"5","article-title":"An overview on the advances of Gymnema sylvestre: chemistry, pharmacology and patents","volume":"58","author":"Porchezhian","year":"2003","journal-title":"Pharmazie"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0075","doi-asserted-by":"crossref","first-page":"77","DOI":"10.3164\/jcbn.2007010","article-title":"Gymnema sylvestre: a Memoir","volume":"41","author":"Kanetkar","year":"2007","journal-title":"J Clin Biochem Nutr"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0080","doi-asserted-by":"crossref","first-page":"4865","DOI":"10.3748\/wjg.15.4865","article-title":"Biochemical mechanisms in drug-induced liver injury: certainties and doubts","volume":"15","author":"Grattagliano","year":"2009","journal-title":"World J Gastroenterol"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0085","doi-asserted-by":"crossref","first-page":"915","DOI":"10.1001\/jama.300.8.915","article-title":"Lead, mercury, and arsenic in US- and Indian-manufactured Ayurvedic medicines sold over the internet","volume":"300","author":"Saper","year":"2008","journal-title":"JAMA"},{"key":"10.1097\/MAJ.0b013e3181f41168_bb0090","doi-asserted-by":"crossref","first-page":"344","DOI":"10.7326\/0003-4819-135-5-200109040-00011","article-title":"Perceptions about complementary therapies relative to conventional therapies among adults who use both: results from a national survey","volume":"135","author":"Eisenberg","year":"2001","journal-title":"Ann Intern Med"}],"container-title":["The American Journal of the Medical Sciences"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000296291531435X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000296291531435X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,6,4]],"date-time":"2019-06-04T18:33:25Z","timestamp":1559673205000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000296291531435X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["S000296291531435X"],"URL":"https:\/\/doi.org\/10.1097\/maj.0b013e3181f41168","relation":{},"ISSN":["0002-9629"],"issn-type":[{"value":"0002-9629","type":"print"}],"subject":[],"published":{"date-parts":[[2010,12]]}}}