{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:18:20Z","timestamp":1786119500259,"version":"build-2736575974"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1097\/mao.0b013e3181e3dedf","type":"journal-article","created":{"date-parts":[[2010,7,2]],"date-time":"2010-07-02T06:56:40Z","timestamp":1278053800000},"page":"867-874","source":"Crossref","is-referenced-by-count":7,"title":["Otosclerosis"],"prefix":"10.1097","volume":"31","author":[{"given":"P\u00e9ter","family":"Csomor","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Istv\u00e1n","family":"Sziklai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"B\u00e1lint","family":"Liktor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L\u00e1szl\u00f3 Z.","family":"Szab\u00f3","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f3zsef","family":"Pytel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00f3zsef","family":"J\u00f3ri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tam\u00e1s","family":"Karosi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-3-20210212","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1097\/00129492-200103000-00023","article-title":"Patophysiology of otosclerosis.","volume":"22","author":"Chole","year":"2001","journal-title":"Otol Neurotol"},{"key":"R2-3-20210212","doi-asserted-by":"crossref","first-page":"705","DOI":"10.3109\/00016489609137910","article-title":"Measles virus in otosclerosis and the specific immune response of the inner ear.","volume":"116","author":"Arnold","year":"1996","journal-title":"Acta Otolaryngol (Stockh)"},{"key":"R3-3-20210212","first-page":"827","article-title":"Polymerase chain reaction amplification of measles virus sequence from human temporal bone sections with active otosclerosis.","volume":"17","author":"McKenna","year":"1996","journal-title":"Am J Otol"},{"key":"R4-3-20210212","doi-asserted-by":"crossref","first-page":"1291","DOI":"10.1097\/01.MLG.0000165462.35495.DF","article-title":"Codetection of measles virus and tumor necrosis factor-alpha mRNA in otosclerotic stapes footplates.","volume":"115","author":"Karosi","year":"2005","journal-title":"Laryngoscope"},{"key":"R5-3-20210212","doi-asserted-by":"crossref","first-page":"1427","DOI":"10.1097\/01.mlg.0000225928.35838.e5","article-title":"Detection of osteoprotegerin and TNF-alpha mRNA in ankylotic stapes footplates in connection with measles virus positivity.","volume":"116","author":"Karosi","year":"2006","journal-title":"Laryngoscope"},{"key":"R6-3-20210212","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1002\/jnr.20764","article-title":"Proinflammatory cytokines expression in noise-induced damaged cochlea.","volume":"83","author":"Fujioka","year":"2006","journal-title":"J Neurosci Res"},{"key":"R7-3-20210212","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1097\/00129492-200303000-00003","article-title":"Sensorineural hearing loss in chronic otitis media.","volume":"24","author":"Papp","year":"2003","journal-title":"Otol Neurotol"},{"key":"R8-3-20210212","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1038\/sj.cdd.4401189","article-title":"Tumor necrosis factor signaling.","volume":"10","author":"Wajant","year":"2003","journal-title":"Cell Death Differ"},{"key":"R9-3-20210212","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1126\/science.1071924","article-title":"TNF-R1 signaling: a beautiful pathway.","volume":"296","author":"Chen","year":"2002","journal-title":"Science"},{"key":"R10-3-20210212","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1600-065X.2008.00755.x","article-title":"TNFR signaling: ubiquitin-conjugated TRAFfic signals control stop-and-go for MAPK signaling complexes.","volume":"228","author":"Karin","year":"2009","journal-title":"Immunol Rev"},{"key":"R11-3-20210212","doi-asserted-by":"crossref","first-page":"1131","DOI":"10.1097\/MAO.0b013e3181be6af4","article-title":"TNF-alpha receptor expression correlates with histologic activity of otosclerosis.","volume":"30","author":"Csomor","year":"2009","journal-title":"Otol Neurotol"},{"key":"R12-3-20210212","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1016\/j.cell.2008.03.036","article-title":"TNF-alpha induces two distinct caspase-8 activation pathways.","volume":"133","author":"Wang","year":"2008","journal-title":"Cell"},{"key":"R13-3-20210212","doi-asserted-by":"crossref","first-page":"35906","DOI":"10.1074\/jbc.M109.072256","article-title":"TRAF2 must bind to cIAPs for TNF to efficiently activate NF-{kappa}B and to prevent TNF-induced apoptosis.","volume":"284","author":"Vince","year":"2009","journal-title":"J Biol Chem"},{"key":"R14-3-20210212","doi-asserted-by":"crossref","first-page":"11778","DOI":"10.1073\/pnas.0711122105","article-title":"Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation.","volume":"105","author":"Mahoney","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R15-3-20210212","doi-asserted-by":"crossref","first-page":"78","DOI":"10.1016\/j.humpath.2005.09.022","article-title":"Expression and localization of inhibitor of apoptosis proteins in normal human tissues.","volume":"37","author":"Vischioni","year":"2006","journal-title":"Hum Pathol"},{"key":"R16-3-20210212","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.immuni.2009.04.011","article-title":"Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.","volume":"30","author":"Bertrand","year":"2009","journal-title":"Immunity"},{"key":"R19-3-20210212","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1128\/MCB.26.2.699-708.2006","article-title":"Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival.","volume":"26","author":"Conte","year":"2006","journal-title":"Mol Cell Biol"},{"key":"R20-3-20210212","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1111\/j.1365-2273.2007.01475.x","article-title":"A review on the genetics of otosclerosis.","volume":"32","author":"Moumoulidis","year":"2007","journal-title":"Clin Otolaryngol"},{"key":"R21-3-20210212","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1016\/S8756-3282(02)00679-8","article-title":"Otosclerosis: a genetically heterogeneous disease involving at least three different genes.","volume":"30","author":"Van Den Bogaert","year":"2002","journal-title":"Bone"},{"key":"R22-3-20210212","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1038\/sj.ejhg.5201761","article-title":"A seventh locus for otosclerosis, OTSC7, maps to chromosome 6q13-16.1.","volume":"15","author":"Thys","year":"2007","journal-title":"Eur J Hum Genet"},{"key":"R23-3-20210212","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1007\/s00439-008-0470-3","article-title":"A new locus for otosclerosis, OTSC8, maps to the pericentromeric region of chromosome 9.","volume":"123","author":"Bel Hadj Ali","year":"2008","journal-title":"Hum Genet"},{"key":"R24-3-20210212","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1097\/MLG.0b013e31817c133d","article-title":"Disease-associated novel CD46 splicing variants and pathologic bone remodeling in otosclerosis.","volume":"118","author":"Karosi","year":"2008","journal-title":"Laryngoscope"},{"key":"R25-3-20210212","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1097\/01.mlg.0000231733.02481.59","article-title":"Glucocorticoids inhibit diastrophic dysplasia sulfate transporter activity in otosclerosis by interleukin-6.","volume":"116","author":"Imauchi","year":"2006","journal-title":"Laryngoscope"},{"key":"R26-3-20210212","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1080\/00016480701299659","article-title":"Immunohistochemical evidence of BMP-2, -4 and -7 activity in otospongiosis.","volume":"128","author":"Lehnerdt","year":"2008","journal-title":"Acta Otolaryngol"},{"key":"R27-3-20210212","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/0378-5955(96)00027-5","article-title":"Human otosclerotic bone-derived peptide decreases the gain of the electromotility in isolated outer hair cells.","volume":"95","author":"Sziklai","year":"1996","journal-title":"Hear Res"},{"key":"R28-3-20210212","doi-asserted-by":"crossref","first-page":"1627","DOI":"10.1097\/00005537-200209000-00019","article-title":"Tumor necrosis factor-alpha, an initiator, and etanercept, an inhibitor of cochlear inflammation.","volume":"112","author":"Satoh","year":"2002","journal-title":"Laryngoscope"},{"key":"R29-3-20210212","doi-asserted-by":"crossref","first-page":"903","DOI":"10.1097\/01.mao.0000185082.28598.87","article-title":"Etanercept treatment for autoimmune inner ear disease: results of a pilot placebo-controlled study.","volume":"26","author":"Cohen","year":"2005","journal-title":"Otol Neurotol"},{"key":"R30-3-20210212","doi-asserted-by":"crossref","first-page":"1064","DOI":"10.1017\/S0022215106002593","article-title":"Etanercept, a tumour necrosis factor alpha receptor antagonist, and methotrexate in acute sensorineural hearing loss.","volume":"120","author":"Street","year":"2006","journal-title":"J Laryngol Otol"}],"container-title":["Otology & Neurotology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/MAO.0b013e3181e3dedf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:22:51Z","timestamp":1786040571000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00129492-201008000-00003"}},"subtitle":["Disturbed Balance Between Cell Survival and Apoptosis"],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010]]}},"URL":"https:\/\/doi.org\/10.1097\/mao.0b013e3181e3dedf","relation":{},"ISSN":["1531-7129"],"issn-type":[{"value":"1531-7129","type":"print"}],"subject":[],"published":{"date-parts":[[2010,8]]}}}