{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T00:04:51Z","timestamp":1792713891768,"version":"4.5.0"},"reference-count":43,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1097\/mao.0b013e3181feb92a","type":"journal-article","created":{"date-parts":[[2010,11,19]],"date-time":"2010-11-19T02:27:12Z","timestamp":1290133632000},"page":"158-162","source":"Crossref","is-referenced-by-count":26,"title":["Estrogen Receptor Expression in Sporadic Vestibular Schwannomas"],"prefix":"10.1097","volume":"32","author":[{"given":"Carrie M.","family":"Brown","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zana K.","family":"Ahmad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allen F.","family":"Ryan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joni K.","family":"Doherty","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-28-20210212","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/00129492-200501000-00016","article-title":"Incidence of vestibular schwannoma and neurofibromatosis 2 in the North West of England over a 10-year period: higher incidence than previously thought.","volume":"26","author":"Evans","year":"2005","journal-title":"Otol Neurotol"},{"key":"R2-28-20210212","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1097\/00005537-199606000-00007","article-title":"Growth rate characteristics of acoustic neuromas associated with neurofibromatosis type 2.","volume":"106","author":"Abaza","year":"1996","journal-title":"Laryngoscope"},{"key":"R3-28-20210212","doi-asserted-by":"crossref","first-page":"1051","DOI":"10.1080\/00016480701200210","article-title":"The prevalence and clinical course of patients with 'incidental' acoustic neuromas.","volume":"127","author":"Jeyakumar","year":"2007","journal-title":"Acta Otolaryngol"},{"key":"R4-28-20210212","first-page":"603","article-title":"A clinical study of type 2 neurofibromatosis.","volume":"84","author":"Evans","year":"1992","journal-title":"Quart J Med"},{"key":"R5-28-20210212","first-page":"97","article-title":"Neurofibromatosis type 2: genetic and clinic features.","volume":"78","author":"Evans","year":"1999","journal-title":"ENT J"},{"key":"R6-28-20210212","first-page":"722","article-title":"Conservative management of unilateral acoustic neuromas.","volume":"21","author":"Taschudi","year":"2000","journal-title":"Am J Otol"},{"key":"R7-28-20210212","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1159\/000156714","article-title":"Facial nerve outcome after microsurgical resection of vestibular schwannoma.","volume":"21","author":"Marouf","year":"2008","journal-title":"Prog Neurol Surg"},{"key":"R9-28-20210212","doi-asserted-by":"crossref","first-page":"28","DOI":"10.3171\/jns.1980.52.1.0028","article-title":"Acoustic neurilemmoma: clinicoanatomic study of 103 patients.","volume":"52","author":"Kasantikul","year":"1980","journal-title":"J Neurosurg"},{"key":"R10-28-20210212","first-page":"88","article-title":"Acoustic neuroma in pregnancy.","volume":"14","author":"Gaughan","year":"1993","journal-title":"Am J Otol"},{"key":"R11-28-20210212","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1097\/MLG.0b013e318177e20b","article-title":"Vestibular schwannoma quantitative polymerase chain reaction expression of estrogen and progesterone receptors.","volume":"118","author":"Patel","year":"2008","journal-title":"Laryngoscope"},{"key":"R12-28-20210212","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0090-3019(81)90023-9","article-title":"Estrogen receptors in acoustic neurilemmomas.","volume":"15","author":"Kasantikul","year":"1981","journal-title":"Surg Neurol"},{"key":"R13-28-20210212","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1017\/S0022215107000229","article-title":"Expression and clinical significance of Ki-67, oestrogen and progesterone receptors in acoustic neuroma.","volume":"122","author":"Cafer","year":"2008","journal-title":"J Laryngol Otol"},{"key":"R14-28-20210212","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/1477-5751-8-9","article-title":"Expression of estrogen and progesterone receptors in vestibular schwannomas and their clinical significance.","volume":"8","author":"Jaiswal","year":"2009","journal-title":"J Negat Results Biomed"},{"key":"R15-28-20210212","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1055\/s-0028-1096198","article-title":"Immunohistochemical investigation of hormone receptors and vascular endothelial growth factor concentration in vestibular schwannoma.","volume":"18","author":"Dalgorf","year":"2008","journal-title":"Skull Base"},{"key":"R16-28-20210212","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1007\/BF01844749","article-title":"Hormone receptors in vestibular schwannomas.","volume":"139","author":"Carroll","year":"1997","journal-title":"Acta Neurochir"},{"key":"R17-28-20210212","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1017\/S0022215100114197","article-title":"Oestrogen and progesterone receptors in acoustic neuroma.","volume":"104","author":"Curley","year":"1990","journal-title":"J Laryngol Otol"},{"key":"R18-28-20210212","first-page":"111","article-title":"Acoustic Neuroma in Pregnancy.","volume":"15","author":"Doyle","year":"1994","journal-title":"Am J Otol"},{"key":"R19-28-20210212","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1001\/archotol.1990.01870020078020","article-title":"Estrogen and progesterone receptors in acoustic neuromas.","volume":"116","author":"Klinken","year":"1990","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"R20-28-20210212","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1080\/00016480050218681","article-title":"Clinicopathologic growth factors in vestibular schwannomas: a morphological and immunohistochemical study of 69 tumors.","volume":"120","author":"Labit-Bouvier","year":"2000","journal-title":"Acta Otolaryngol"},{"key":"R21-28-20210212","first-page":"237","article-title":"Sex hormone receptors in acoustic neuromas.","volume":"11","author":"Siglock","year":"1990","journal-title":"Am J Otol"},{"key":"R22-28-20210212","first-page":"303","article-title":"Sex hormone receptors in intracranial tumours and normal brain.","volume":"13","author":"Whittle","year":"1987","journal-title":"Eur J Surg Oncol"},{"key":"R23-28-20210212","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1288\/00005537-199507000-00005","article-title":"Acoustic schwannoma and pregnancy: a DNA flow cytometric, steroid hormone receptor, and proliferation marker study.","volume":"105","author":"Beatty","year":"1995","journal-title":"Laryngoscope"},{"key":"R24-28-20210212","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/j.1365-2273.1995.tb00073.x","article-title":"Expression of steroid receptors in acoustic neuroma.","volume":"20","author":"Filipo","year":"1995","journal-title":"Clin Otolaryngol"},{"key":"R25-28-20210212","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/0090-3019(86)90366-6","article-title":"Estrogen and progestin receptors in acoustic and spinal neurilemmomas.","volume":"26","author":"Markwalder","year":"1986","journal-title":"Surg Neurol"},{"key":"R26-28-20210212","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1227\/00006123-198112000-00009","article-title":"Specific estradiol binding in schwannomas, meningiomas, neurofibromas.","volume":"9","author":"Martuza","year":"1980","journal-title":"Neurosurgery"},{"key":"R27-28-20210212","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1177\/019459989010300307","article-title":"Estrogen and progesterone binding by acoustic neuroma tissue.","volume":"103","author":"Monsell","year":"1990","journal-title":"Otolaryngol Head Neck Surg"},{"key":"R28-28-20210212","doi-asserted-by":"crossref","first-page":"2727","DOI":"10.1001\/jama.295.23.joc60074","article-title":"Effects of tamoxifen vs raloxifene on the risk of developing invasive breast cancer and other disease outcomes: The NSABP Study of Tamoxifen and Raloxifene (STAR) P-2 trial.","volume":"295","author":"Vogel","year":"2006","journal-title":"JAMA"},{"key":"R31-28-20210212","first-page":"630","article-title":"Immunohistochemical identification of tumor markers in metastatic adenocarcinoma of the colon, pancreas, and lung.","volume":"118","author":"Brown","year":"1994","journal-title":"Arch Pathol Lab Med"},{"key":"R32-28-20210212","doi-asserted-by":"crossref","first-page":"1467","DOI":"10.5858\/2000-124-1467-EAPRIN","article-title":"Estrogen and progesterone receptors in non-small cell lung cancer in 248 consecutive patients who underwent surgical resection.","volume":"124","author":"Di Nunno","year":"2000","journal-title":"Arch Pathol Lab Med"},{"key":"R33-28-20210212","first-page":"2141","article-title":"Human non-small cell lung tumors and cells derived from normal lung express both estrogen receptor and and show biological responses to estrogen.","volume":"62","author":"Stabile","year":"2002","journal-title":"Cancer Res"},{"key":"R34-28-20210212","doi-asserted-by":"crossref","first-page":"262","DOI":"10.1016\/S0194-5998(99)70416-X","article-title":"Effects of estrogen and tamoxifen on growth of human vestibular schwannomas in the nude mouse.","volume":"120","author":"Stidham","year":"1999","journal-title":"Otolaryngol Head Neck Surg"},{"key":"R35-28-20210212","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1097\/00005537-199604000-00012","article-title":"Epidermal growth factor receptor expression by acoustic neuromas.","volume":"106","author":"Sturgis","year":"1996","journal-title":"Laryngoscope"},{"key":"R36-28-20210212","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1002\/glia.20316","article-title":"Constitutive neuregulin-1\/ErbB signaling contributes to human vestibular schwannoma proliferation.","volume":"53","author":"Hansen","year":"2006","journal-title":"Glia"},{"key":"R37-28-20210212","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1097\/mao.0b013e31815d4429","article-title":"ErbB and nrg: potential molecular targets for vestibular schwannoma pharmacotherapy.","volume":"29","author":"Doherty","year":"2007","journal-title":"Otol Neurotol"},{"key":"R38-28-20210212","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1097\/MAO.0b013e31817f7398","article-title":"The ErbB inhibitors traztuzumab and erlotinib inhibit growth of vestibular schwannoma xenografts in nude mice: a preliminary study.","volume":"29","author":"Hansen","year":"2008","journal-title":"Otol Neurotol"},{"key":"R39-28-20210212","doi-asserted-by":"crossref","first-page":"5236","DOI":"10.1158\/0008-5472.CAN-07-5849","article-title":"Dissecting and targeting the growth factor-dependent and growth factor-independent extracellular signal-regulated kinase pathway in human schwannoma.","volume":"68","author":"Ammoun","year":"2008","journal-title":"Cancer Res"},{"key":"R40-28-20210212","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1210\/me.2002-0368","article-title":"Bidirectional signaling between the estrogen receptor and the epidermal growth factor receptor.","volume":"17","author":"Levin","year":"2002","journal-title":"Mol Endocrinol"},{"key":"R41-28-20210212","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1126\/science.270.5241.1491","article-title":"Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase.","volume":"270","author":"Kato","year":"1995","journal-title":"Science"},{"key":"R42-28-20210212","doi-asserted-by":"crossref","first-page":"2174","DOI":"10.1002\/j.1460-2075.1996.tb00571.x","article-title":"Activation of the unliganded estrogen receptor by EGF involves the MAP kinase pathway and direct phosphorylation.","volume":"15","author":"Bunone","year":"1996","journal-title":"EMBO"},{"key":"R43-28-20210212","first-page":"307","article-title":"Cell membrane and nuclear estrogen receptors derive from a single transcript: studies of ER and ER expressed in CHO cells.","volume":"13","author":"Razandi","year":"1999","journal-title":"Mol Endocrinol"},{"key":"R44-28-20210212","first-page":"4429","article-title":"Cross-talk among estrogen receptor, epidermal growth factor and insulin-like growth factor signaling in breast cancer.","volume":"7","author":"Lee","year":"2001","journal-title":"Clin Cancer Res"},{"key":"R45-28-20210212","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1210\/endo-118-1-138","article-title":"Induction of epidermal growth factor-related polypeptides by 17 -estradiol in MCF-7 human breast cancer cells.","volume":"118","author":"Dickson","year":"1986","journal-title":"Endocrinology"},{"key":"R46-28-20210212","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1038\/sj.bjc.6601504","article-title":"Additive antitumour effect of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib (Iressa, ZD1839) and the antioestrogen fulvestrant (Faslodex, ICI I 82,780) in breast cancer cells.","volume":"90","author":"Okubo","year":"2004","journal-title":"Br J Cancer"}],"container-title":["Otology & Neurotology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/MAO.0b013e3181feb92a","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:38:16Z","timestamp":1786041496000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00129492-201101000-00028"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1097\/mao.0b013e3181feb92a","relation":{},"ISSN":["1531-7129"],"issn-type":[{"value":"1531-7129","type":"print"}],"subject":[],"published":{"date-parts":[[2011,1]]}}}