{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:18:53Z","timestamp":1786119533616,"version":"build-2736575974"},"reference-count":33,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,2]]},"DOI":"10.1097\/mao.0b013e3182016332","type":"journal-article","created":{"date-parts":[[2010,12,11]],"date-time":"2010-12-11T02:25:52Z","timestamp":1292034352000},"page":"204-212","source":"Crossref","is-referenced-by-count":10,"title":["Transport Augmentation Through the Blood-Inner Ear Barriers of Guinea Pigs Treated With 3-Nitropropionic Acid and Patients With Acute Hearing Loss, Visualized With 3.0 T MRI"],"prefix":"10.1097","volume":"32","author":[{"given":"Jing","family":"Zou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ya","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guiliang","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donghui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyue","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongliang","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-4-20210212","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1177\/000348947608500117","article-title":"Sudden deafness of vascular origin: a human temporal bone study.","volume":"85","author":"Gussen","year":"1976","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"R2-4-20210212","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1159\/000312640","article-title":"Cardiovascular and thromboembolic risk factors in idiopathic sudden sensorineural hearing loss: a case-control study.","volume":"16","author":"Mosnier","year":"2010","journal-title":"Audiol Neurootol"},{"key":"R3-4-20210212","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1016\/S0140-6736(09)62071-7","article-title":"Sudden sensorineural hearing loss.","volume":"375","author":"Schreiber","year":"2010","journal-title":"Lancet"},{"key":"R4-4-20210212","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1177\/000348940411300605","article-title":"Immune-mediated disorders associated with idiopathic sudden sensorineural hearing loss.","volume":"113","author":"Toubi","year":"2004","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"R5-4-20210212","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1097\/00129492-200503000-00004","article-title":"Pathology and pathophysiology of idiopathic sudden sensorineural hearing loss.","volume":"26","author":"Merchant","year":"2005","journal-title":"Otol Neurotol"},{"key":"R6-4-20210212","first-page":"530","article-title":"Mitochondrial role in hair cell survival after injury.","volume":"113","author":"Hyde","year":"1995","journal-title":"Otolaryngol Head Neck Surg"},{"key":"R7-4-20210212","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1258\/0022215011907514","article-title":"Sudden bilateral hearing loss and sporadic mitochondrial DNA deletion.","volume":"115","author":"Berrettini","year":"2001","journal-title":"J Laryngol Otol"},{"key":"R8-4-20210212","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0378-5955(02)00338-6","article-title":"Involvement of the mitochondrial permeability transition in gentamicin ototoxicity.","volume":"169","author":"Dehne","year":"2002","journal-title":"Hear Res"},{"key":"R9-4-20210212","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1002\/jnr.20832","article-title":"A BAD link to mitochondrial cell death in the cochlea of mice with noise-induced hearing loss.","volume":"83","author":"Vicente-Torres","year":"2006","journal-title":"J Neurosci Res"},{"key":"R10-4-20210212","doi-asserted-by":"crossref","first-page":"931","DOI":"10.1038\/sj.ki.5002434","article-title":"Ototoxicity.","volume":"72","author":"Rybak","year":"2007","journal-title":"Kidney Int"},{"key":"R11-4-20210212","doi-asserted-by":"crossref","first-page":"1597","DOI":"10.1097\/01.wnr.0000133226.94662.80","article-title":"A novel animal model of acute cochlear mitochondrial dysfunction.","volume":"15","author":"Hoya","year":"2004","journal-title":"Neuroreport"},{"key":"R12-4-20210212","first-page":"1317","article-title":"Observations on the pathology of Meniere's syndrome: (section of otology).","volume":"31","author":"Hallpike","year":"1938","journal-title":"Proc R Soc Med"},{"key":"R13-4-20210212","doi-asserted-by":"crossref","first-page":"445","DOI":"10.3109\/00016488509108936","article-title":"The cause (multifactorial inheritance) and pathogenesis (endolymphatic malabsorption) of Meniere's disease and its symptoms (mechanical and chemical).","volume":"99","author":"Paparella","year":"1985","journal-title":"Acta Otolaryngol"},{"key":"R14-4-20210212","first-page":"648","article-title":"Serum antibodies against heat shock protein 70 in Meniere's disease.","volume":"16","author":"Rauch","year":"1995","journal-title":"Am J Otol"},{"key":"R15-4-20210212","doi-asserted-by":"crossref","first-page":"658","DOI":"10.3109\/00016489209137456","article-title":"Ischemia of the endolymphatic sac.","volume":"112","author":"Lee","year":"1992","journal-title":"Acta Otolaryngol"},{"key":"R16-4-20210212","first-page":"639","article-title":"Detection of viral DNA in endolymphatic sac tissue from Meniere's disease patients.","volume":"15","author":"Welling","year":"1994","journal-title":"Am J Otol"},{"key":"R17-4-20210212","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1007\/s00405-004-0816-y","article-title":"Incidence of virus infection as a cause of Meniere's disease or endolymphatic hydrops assessed by electrocochleography.","volume":"262","author":"Selmani","year":"2005","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"R19-4-20210212","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1007\/PL00007522","article-title":"Cochlear ultrastructure in two-phase endolymphatic hydrops in the guinea-pig.","volume":"259","author":"Dunnebier","year":"2002","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"R20-4-20210212","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1177\/000348949510400306","article-title":"Vascular permeability of the stria vascularis and morphology of the endolymphatic sac in two types of experimental endolymphatic hydrops.","volume":"104","author":"Sakagami","year":"1995","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"R23-4-20210212","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1177\/000348940311201212","article-title":"In vivo visualization of endolymphatic hydrops in guinea pigs: magnetic resonance imaging evaluation at 4.7 Tesla.","volume":"112","author":"Zou","year":"2003","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"R24-4-20210212","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1080\/16513860701305578","article-title":"In vivo MRI visualization of endolymphatic hydrops induced by keyhole limpet hemocyanin round window immunization.","volume":"5","author":"Zou","year":"2007","journal-title":"Audiol Med"},{"key":"R26-4-20210212","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.otohns.2009.10.006","article-title":"Magnetic resonance imaging of guinea pig cochlea after vasopressin-induced or surgically induced endolymphatic hydrops.","volume":"142","author":"Marshall","year":"2010","journal-title":"Otolaryngol Head Neck Surg"},{"key":"R27-4-20210212","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1177\/000348949210100601","article-title":"Labyrinthine enhancement on gadolinium-enhanced magnetic resonance imaging in sudden deafness and vertigo: correlation with audiologic and electronystagmographic studies.","volume":"101","author":"Mark","year":"1992","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"R28-4-20210212","doi-asserted-by":"crossref","first-page":"2650","DOI":"10.1007\/s00330-003-1922-8","article-title":"High-resolution T1-weighted 3D real IR imaging of the temporal bone using triple-dose contrast material.","volume":"13","author":"Naganawa","year":"2003","journal-title":"Eur Radiol"},{"key":"R29-4-20210212","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1007\/s00330-005-0046-8","article-title":"Observation of contrast enhancement in the cochlear fluid space of healthy subjects using a 3D-FLAIR sequence at 3 Tesla.","volume":"16","author":"Naganawa","year":"2006","journal-title":"Eur Radiol"},{"key":"R30-4-20210212","doi-asserted-by":"crossref","first-page":"665","DOI":"10.3109\/00016480903384176","article-title":"3 Tesla magnetic resonance imaging obtained 4 hours after intravenous gadolinium injection in patients with sudden deafness.","volume":"130","author":"Tagaya","year":"2010","journal-title":"Acta Otolaryngol"},{"key":"R31-4-20210212","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.heares.2009.09.015","article-title":"Differential passage of gadolinium through the mouse inner ear barriers evaluated with 4.7T MRI.","volume":"259","author":"Zou","year":"2010","journal-title":"Hearing Res"},{"key":"R32-4-20210212","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1159\/000084024","article-title":"Communication between the perilymphatic scalae and spiral ligament visualized by in vivo MRI.","volume":"10","author":"Zou","year":"2005","journal-title":"Audiol Neurootol"},{"key":"R33-4-20210212","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1097\/00001756-200408260-00019","article-title":"Imaging of the guinea pig cochlea following round window gadolinium application.","volume":"15","author":"Duan","year":"2004","journal-title":"Neuroreport"},{"key":"R34-4-20210212","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1097\/MLG.0b013e31802c300c","article-title":"Visualization of endolymphatic hydrops in patients with Meniere's disease.","volume":"117","author":"Nakashima","year":"2007","journal-title":"Laryngoscope"},{"key":"R36-4-20210212","doi-asserted-by":"crossref","first-page":"3979","DOI":"10.1097\/00001756-200012180-00015","article-title":"Magnetic resonance imaging of the membranous labyrinth during in vivo gadolinium (Gd-DTPA-BMA) uptake in the normal and lesioned cochlea.","volume":"11","author":"Counter","year":"2000","journal-title":"Neuroreport"},{"key":"R37-4-20210212","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1080\/00016480310000548","article-title":"In vivo observation of dynamic perilymph formation using 4.7 T MRI with gadolinium as a tracer.","volume":"123","author":"Zou","year":"2003","journal-title":"Acta Otolaryngol"},{"key":"R38-4-20210212","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1007\/s00234-003-1051-8","article-title":"Contrast enhancement of the cochlear aqueduct in MR imaging: its frequency and clinical significance.","volume":"45","author":"Nakamura","year":"2003","journal-title":"Neuroradiology"}],"container-title":["Otology &amp; Neurotology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/MAO.0b013e3182016332","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:46:06Z","timestamp":1786041966000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00129492-201102000-00004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,2]]},"references-count":33,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1097\/mao.0b013e3182016332","relation":{},"ISSN":["1531-7129"],"issn-type":[{"value":"1531-7129","type":"print"}],"subject":[],"published":{"date-parts":[[2011,2]]}}}