{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T23:55:47Z","timestamp":1791330947610,"version":"4.3.1"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,10]]},"DOI":"10.1097\/mao.0b013e31822e96bc","type":"journal-article","created":{"date-parts":[[2011,10,4]],"date-time":"2011-10-04T18:16:10Z","timestamp":1317752170000},"page":"1224-1229","source":"Crossref","is-referenced-by-count":26,"title":["The Impact of Platelet-Derived Growth Factor on Closure of Chronic Tympanic Membrane Perforations"],"prefix":"10.1097","volume":"32","author":[{"given":"Christof","family":"R\u00f6\u00f6sli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Toni","family":"von B\u00fcren","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas B.","family":"Gassmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex M.","family":"Huber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-7-20210212","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/S0030-6665(20)30467-9","article-title":"Tympanic membrane wound healing. An overview.","volume":"28","author":"Gladstone","year":"1995","journal-title":"Otolaryngol Clin North Am"},{"key":"R3-7-20210212","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3109\/00016488509108589","article-title":"Histology of the tympanic perforation and the replacement membrane.","volume":"100","author":"Yamashita","year":"1985","journal-title":"Acta Otolaryngol (Stockh)"},{"key":"R4-7-20210212","doi-asserted-by":"crossref","first-page":"297","DOI":"10.3109\/00016488809097011","article-title":"Histological study of the thin replacement membrane of human tympanic membrane perforations.","volume":"105","author":"Govaerts","year":"1988","journal-title":"Acta Otolaryngol (Stockh)"},{"key":"R5-7-20210212","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1177\/019459988809800211","article-title":"Long-term results of tympanic membrane repair.","volume":"98","author":"Halik","year":"1988","journal-title":"Otolaryngol Head Neck Surg"},{"key":"R6-7-20210212","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1017\/S0022215109004368","article-title":"Myringoplasty: impact of perforation size on closure and audiological improvement.","volume":"123","author":"Wasson","year":"2009","journal-title":"Laryngol Otol"},{"key":"R7-7-20210212","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1046\/j.1365-2273.1999.00227.x","article-title":"Myringoplasty: a prospective audit study.","volume":"24","author":"Kotecha","year":"1999","journal-title":"Clin Otolaryngol Allied Sci"},{"key":"R8-7-20210212","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1080\/000164802320396259","article-title":"Topical treatment with growth factors for tympanic membrane perforations: progress towards clinical application.","volume":"122","author":"Ma","year":"2002","journal-title":"Acta Otolaryngol"},{"key":"R9-7-20210212","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/S0094-1298(20)30617-9","article-title":"Peptide growth factors and wound healing.","volume":"17","author":"McGrath","year":"1990","journal-title":"Clin Plast Surg"},{"key":"R10-7-20210212","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1177\/000348949210100411","article-title":"Angiogenic growth factors: their effect and potential in soft tissue healing.","volume":"101","author":"Hom","year":"1992","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"R11-7-20210212","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1021\/bi00453a022","article-title":"Purification of PDGF-AB and PDGF-BB from human platelet extracts and identification of all three PDGF dimers in human platelets.","volume":"29","author":"Hart","year":"1990","journal-title":"Biochemistry"},{"key":"R12-7-20210212","doi-asserted-by":"crossref","first-page":"7696","DOI":"10.1073\/pnas.84.21.7696","article-title":"Role of platelet-derived growth factors in wound healing: synergistic effects with other growth factors.","volume":"84","author":"Lynch","year":"1987","journal-title":"Proc Natl Acad Sci USA"},{"key":"R13-7-20210212","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1097\/00000658-198609000-00011","article-title":"Classification and treatment of chronic non-healing wounds: successful treatment with autologous platelet-derived wound healing factors (PDWHF).","volume":"204","author":"Knighton","year":"1986","journal-title":"Ann Surg"},{"key":"R14-7-20210212","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/0140-6736(92)90143-Q","article-title":"Platelet-derived growth factor BB for the treatment of chronic pressure ulcers.","volume":"339","author":"Robson","year":"1992","journal-title":"Lancet"},{"key":"R15-7-20210212","doi-asserted-by":"crossref","first-page":"1224","DOI":"10.1902\/jop.1996.67.11.1224","article-title":"The effects of platelet-derived growth factor-BB and insulin-like growth factor-1 on epithelial dysplasia.","volume":"67","author":"Shih","year":"1996","journal-title":"J Periodontol"},{"key":"R16-7-20210212","doi-asserted-by":"crossref","first-page":"455","DOI":"10.2165\/11534570-000000000-00000","article-title":"Benefit-risk assessment of becaplermin in the treatment of diabetic foot ulcers.","volume":"33","author":"Papanas","year":"2010","journal-title":"Drug Saf"},{"key":"R17-7-20210212","first-page":"506","article-title":"Treatment of chronic tympanic-membrane perforations with a platelet-derived releasate.","volume":"17","author":"Soumekh","year":"1996","journal-title":"Am J Otol"},{"key":"R18-7-20210212","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/S0196-0709(00)85017-6","article-title":"Effects of platelet-derived growth factor-AA on the healing process of tympanic membrane perforation.","volume":"21","author":"Yeo","year":"2000","journal-title":"Am J Otol"},{"key":"R21-7-20210212","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1097\/MAO.0b013e3181c34f01","article-title":"Basic fibroblast growth factor combined with atelocollagen for closing chronic tympanic membrane perforations in 87 patients.","volume":"31","author":"Hakuba","year":"2010","journal-title":"Otol Neurotol"},{"key":"R22-7-20210212","first-page":"10","article-title":"Repair of chronic tympanic membrane perforations using epidermal growth factor: progress toward clinical application.","volume":"15","author":"Lee","year":"1994","journal-title":"Am J Otol"},{"key":"R23-7-20210212","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1016\/j.otohns.2008.01.003","article-title":"Comparison of paper-patch, fat, and perichondrium myringoplasty in repair of small tympanic membrane perforations.","volume":"138","author":"Dursun","year":"2008","journal-title":"Otolaryngol Head Neck Surg"},{"key":"R24-7-20210212","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1080\/00016480600678797","article-title":"Effectiveness of MeroGel hyaluronic acid on tympanic membrane perforations.","volume":"126","author":"Ozturk","year":"2006","journal-title":"Acta Otolaryngol"},{"key":"R25-7-20210212","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1001\/archotol.1988.01860240085029","article-title":"Hyaluronan improves the healing of experimental tympanic membrane perforations.","volume":"114","author":"Laurent","year":"1988","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"R26-7-20210212","doi-asserted-by":"crossref","first-page":"265","DOI":"10.3109\/08977199109000290","article-title":"Improved healing of tympanic membrane perforations with basic fibroblast growth factor.","volume":"5","author":"Fina","year":"1991","journal-title":"Growth Factors"},{"key":"R27-7-20210212","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1288\/00005537-199303000-00012","article-title":"Histological study of the healing of traumatic tympanic membrane perforations after basic fibroblast growth factor application.","volume":"103","author":"Mondain","year":"1993","journal-title":"Laryngoscope"},{"key":"R28-7-20210212","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1288\/00005537-199409000-00002","article-title":"Evaluation of basic fibroblast growth factor in tympanic membrane repair.","volume":"104","author":"Vrabec","year":"1994","journal-title":"Layngoscope"},{"key":"R29-7-20210212","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/S0194-5998(95)70071-4","article-title":"Effect of epidermal growth factor on tympanic membranes with chronic perforations: a clinical trial.","volume":"113","author":"Ramsey","year":"1995","journal-title":"Otolaryngol Head Neck Surg"},{"key":"R30-7-20210212","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1111\/j.1749-4486.2008.01764.x","article-title":"Determinants of spontaneous healing in traumatic perforations of the tympanic membrane.","volume":"33","author":"Orji","year":"2008","journal-title":"Clin Otolaryngol"}],"container-title":["Otology & Neurotology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/MAO.0b013e31822e96bc","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T02:51:00Z","timestamp":1620960660000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00129492-201110000-00007"}},"subtitle":["A Randomized, Double-Blind, Placebo-Controlled Study"],"short-title":[],"issued":{"date-parts":[[2011,10]]},"references-count":27,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1097\/mao.0b013e31822e96bc","relation":{},"ISSN":["1531-7129"],"issn-type":[{"value":"1531-7129","type":"print"}],"subject":[],"published":{"date-parts":[[2011,10]]}}}