{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T03:37:58Z","timestamp":1792640278173,"version":"4.5.0"},"reference-count":6,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Lung transplantation is the only treatment option for patients suffering form end-stage respiratory failure. To date, no mechanical device is available to support patients on the waiting list up to months. Here, we summarize our experience with our first two patients, who were supported with a paracorporeal artificial lung (PAL) placed in parallel to the pulmonary circulation with connection to the pulmonary artery and to the left atrium. A low resistance membrane oxygenator (iLA, Novalung, Hirrlingen, Germany) was attached in both patients. Our first patient suffering from a pulmonary veno-occlusive disease was supported for 18 days until he died due to severe sepsis. Our second patient with a primary pulmonary hypertension of unknown origin was supported 62 days followed by successful lung transplantation. In conclusion, the experience obtained with these first two patients under PAL encourages further studies and introduction of this promising concept into clinical practice.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/mat.0b013e31819740a0","type":"journal-article","created":{"date-parts":[[2009,5,21]],"date-time":"2009-05-21T12:12:54Z","timestamp":1242907974000},"page":"304-306","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":37,"title":["First Experience With a Paracorporeal Artificial Lung In Humans"],"prefix":"10.1097","volume":"55","author":[{"given":"Daniele","family":"Camboni","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alois","family":"Philipp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthias","family":"Arlt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Pfeiffer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Hilker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christof","family":"Schmid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-25-20260730","doi-asserted-by":"crossref","first-page":"956","DOI":"10.1016\/j.healun.2005.05.019","article-title":"Registry of the International Society for Heart and Lung Transplantation. Twenty second official adult lung and heart transplant report.","volume":"24","author":"Trulock","year":"2005","journal-title":"J Heart Lung Trans"},{"key":"R2-25-20260730","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.athoracsur.2008.04.045","article-title":"Pumpless extracorporeal lung assist: A 10-year institutional experience.","volume":"86","author":"Fl\u00f6rchinger","year":"2008","journal-title":"Ann Thorac Surg"},{"key":"R3-25-20260730","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/j.athoracsur.2007.12.032","article-title":"Bridge to lung transplantation through a pulmonary artery to left artial oxygenator circuit.","volume":"85","author":"Schmid","year":"2008","journal-title":"Ann Thorac Surg"},{"key":"R4-25-20260730","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1001\/jama.1965.03080040043012","article-title":"An implantable artificial lung.","volume":"191","author":"Bodell","year":"1965","journal-title":"JAMA"},{"key":"R5-25-20260730","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1097\/01.mat.0000176140.19621.55","article-title":"Development of ambulatory arterio-venous carbon dioxide removal (AVCO2R): The downsized gas exchanger prototype for ambulation removes enough CO2 with low blood resistance.","volume":"51","author":"Wang","year":"2005","journal-title":"ASAIO J"},{"key":"R6-25-20260730","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1016\/j.athoracsur.2007.03.016","article-title":"Seven day, in parallel artificial lung testing in sheep.","volume":"84","author":"Sato","year":"2007","journal-title":"Ann Thorac Surg"}],"container-title":["ASAIO Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/00002480-200905000-00025","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T06:00:34Z","timestamp":1785391234000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00002480-200905000-00025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,5]]},"references-count":6,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1097\/mat.0b013e31819740a0","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1157771.618995","asserted-by":"object"}]},"ISSN":["1058-2916"],"issn-type":[{"value":"1058-2916","type":"print"}],"subject":[],"published":{"date-parts":[[2009,5]]}}}