{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,18]],"date-time":"2025-06-18T04:26:44Z","timestamp":1750220804907,"version":"3.41.0"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,4]]},"abstract":"<jats:sec>\n            <jats:title\/>\n            <jats:p>We aimed to investigate the association of lung involvement and biochemical parameters with patients\u2019 demographic characteristics, and how this association effects the disease course and mortality in elderly patients diagnosed with coronavirus disease 2019 (COVID-19). Age, degree of pulmonary involvement, comorbidities, and biochemical parameters of 211 patients who were 60\u200ayears or older, diagnosed with COVID-19, and had lung involvement were analyzed. The effects of these parameters on ICU admission and mortality were investigated. Advanced age, severity of lung involvement, elevated D-dimer, ferritin, and fibrinogen levels, and a previous history ofchronic obstructive pulmonary disease (COPD)were significant for predicting ICU admission and mortality. Along with advanced age, both the severity of lung involvement and a history of COPD had major impact on mortality in the course of COVID-19.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/mbc.0000000000001119","type":"journal-article","created":{"date-parts":[[2021,12,23]],"date-time":"2021-12-23T15:07:17Z","timestamp":1640272037000},"page":"162-166","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["The effects of lung involvement, clinical and laboratory parameters on outcome in elderly patients with coronavirus disease 2019"],"prefix":"10.1097","volume":"33","author":[{"given":"Ferda","family":"Bilgir","sequence":"first","affiliation":[{"name":"Department of Allergy and Immunology, Ataturk Training and Research Hospital, Izmir Katip \u00c7elebi University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u015eebnem","family":"\u00c7alik","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology, Izmir Bozyaka Training and Research Hospital, University of Health Sciences, Izmir, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ismail","family":"Demir","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zden Y.i.ldirim","family":"Akan","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oktay","family":"Bilgir","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2021,12,22]]},"reference":[{"key":"R1-20250617","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/S0140-6736(20)30183-5","article-title":"Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China","volume":"395","author":"Huang","year":"2020","journal-title":"Lancet"},{"key":"R2-20250617","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1056\/NEJMoa2001017","article-title":"China Novel Coronavirus Investigating and Research Team. 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