{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:10:44Z","timestamp":1786119044020,"version":"build-2736575974"},"reference-count":29,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2009,1]]},"DOI":"10.1097\/mbc.0b013e328313fc8e","type":"journal-article","created":{"date-parts":[[2008,12,22]],"date-time":"2008-12-22T03:13:41Z","timestamp":1229915621000},"page":"4-11","source":"Crossref","is-referenced-by-count":12,"title":["Epidemiological survey of haemophiliacs with inhibitors in France: orthopaedic status, quality of life and cost \u2013 the \u2018Statut Orthop\u00e9dique des Patients H\u00e9mophiles\u2019 avec Inhibiteur study"],"prefix":"10.1097","volume":"20","author":[{"given":"Natalie","family":"Stieltjes","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie F","family":"Torchet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laure","family":"Misrahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Val\u00e9rie","family":"Roussel-Robert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thierry","family":"Lambert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claude","family":"Gu\u00e9rois","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie A","family":"Bertrand","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie E","family":"Briquel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annie","family":"Borel-Derlon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e9rard","family":"Dirat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-2-20210203","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1111\/j.1365-2796.1992.tb00546.x","article-title":"Twenty-five years' experience of prophylactic treatment in severe haemophilia A and B","volume":"232","author":"Nilsson","year":"1992","journal-title":"J Intern Med"},{"key":"R2-2-20210203","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1055\/s-2003-37971","article-title":"Prophylaxis for severe hemophilia: experience from Europe and the United States","volume":"29","author":"van den Berg","year":"2003","journal-title":"Semin Thromb Hemost"},{"key":"R3-2-20210203","doi-asserted-by":"crossref","first-page":"3494","DOI":"10.1182\/blood-2004-05-2008","article-title":"Thirty years of hemophilia treatment in the Netherlands, 1972\u20132001","volume":"104","author":"Plug","year":"2004","journal-title":"Blood"},{"key":"R4-2-20210203","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/S0268-960X(03)00038-9","article-title":"Prophylactic factor replacement in hemophilia","volume":"18","author":"Carcao","year":"2004","journal-title":"Blood Rev"},{"key":"R5-2-20210203","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1046\/j.1365-2516.2003.00780.x","article-title":"The epidemiology of inhibitors in haemophilia A: a systematic review","volume":"9","author":"Wight","year":"2003","journal-title":"Haemophilia"},{"key":"R6-2-20210203","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/S0887-7963(87)70012-1","article-title":"Management of patients with factor VIII inhibitors","volume":"1","author":"Lusher","year":"1987","journal-title":"Transfus Med Rev"},{"key":"R7-2-20210203","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1097\/00001721-199803000-00002","article-title":"Clinical experience with recombinant factor VIIa","volume":"9","author":"Lusher","year":"1998","journal-title":"Blood Coagul Fibrinolysis"},{"key":"R8-2-20210203","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1055\/s-2000-8453","article-title":"Recombinant coagulation factor VIIa: from the concept to clinical application in hemophilia treatment in 2000","volume":"26","author":"Hedner","year":"2000","journal-title":"Semin Thromb Hemost"},{"issue":"3 Suppl 2","key":"R9-2-20210203","first-page":"3","article-title":"Prophylaxis: musculoskeletal evaluation","volume":"30","author":"Gilbert","year":"1993","journal-title":"Semin Hematol"},{"key":"R10-2-20210203","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1111\/j.1651-2227.1981.tb05741.x","article-title":"Radiologic evaluation of prophylaxis in severe haemophilia","volume":"70","author":"Pettersson","year":"1981","journal-title":"Acta Paediatr Scand"},{"key":"R11-2-20210203","article-title":"Quality of life and pharmacoeconomics in clinical trials. 2nd ed","author":"Ware","year":"1996"},{"key":"R12-2-20210203","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1097\/00005650-199603000-00003","article-title":"A 12-item short-form health survey: construction of scales and preliminary tests of reliability and validity","volume":"34","author":"Ware","year":"1996","journal-title":"Med Care"},{"key":"R14-2-20210203","first-page":"445","article-title":"Medico-economic assessment in the early third millennium","volume":"7","author":"Jasso-Mosqueda","year":"2001","journal-title":"H\u00e9matologie"},{"key":"R15-2-20210203","first-page":"323","article-title":"15 Description of the management of severe haemophilia A with the computerized patient's information programme: interests and limits","volume":"6","author":"Jasso-Mosqueda","year":"2000","journal-title":"J d'economie M\u00e9d"},{"key":"R16-2-20210203","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1055\/s-0038-1648507","article-title":"Prevalence of inhibitors in a population of 3435 hemophilia patients in France. French hemophilia study group","volume":"67","author":"Sultan","year":"1992","journal-title":"Thromb Haemost"},{"key":"R18-2-20210203","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1046\/j.1365-2516.2000.00358.x","article-title":"Epidemiological survey of the orthopaedic status of severe haemophilia A and B patients in France. The French Study Group. secretariat","volume":"6","author":"Molho","year":"2000","journal-title":"Haemophilia"},{"key":"R19-2-20210203","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1046\/j.1365-2516.2000.00397.x","article-title":"The orthopaedic status of severe haemophiliacs in Spain","volume":"6","author":"Aznar","year":"2000","journal-title":"Haemophilia"},{"key":"R20-2-20210203","doi-asserted-by":"crossref","first-page":"2358","DOI":"10.1182\/blood-2003-03-0941","article-title":"Cost of care and quality of life for patients with hemophilia complicated by inhibitors: the COCIS study group","volume":"102","author":"Gringeri","year":"2003","journal-title":"Blood"},{"key":"R21-2-20210203","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1111\/j.1365-2516.2005.01065.x","article-title":"Effects of haemophilic arthropathy on health-related quality of life and socio-economic parameters","volume":"11","author":"Fischer","year":"2005","journal-title":"Haemophilia"},{"key":"R22-2-20210203","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1111\/j.1365-2516.2006.01204.x","article-title":"Quality of life is associated to the orthopaedic status in haemophilic patients with inhibitors","volume":"12","author":"Scalone","year":"2006","journal-title":"Haemophilia"},{"issue":"Suppl 2","key":"R23-2-20210203","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1365-2516.2004.00941.x","article-title":"Consensus perspectives on surgery in haemophilia patients with inhibitors: summary statement","volume":"10","author":"Rodriguez-Merchan","year":"2004","journal-title":"Haemophilia"},{"issue":"Suppl 1","key":"R24-2-20210203","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1111\/j.1365-2516.2005.01155.x","article-title":"Case studies: orthopaedic surgery in adult patients with haemophilia A with inhibitors","volume":"11","author":"Goddard","year":"2005","journal-title":"Haemophilia"},{"key":"R25-2-20210203","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1046\/j.1365-2516.1999.00368.x","article-title":"Hemophilia. Treatment of patients with inhibitors: cost issues","volume":"5","author":"Goudemand","year":"1999","journal-title":"Haemophilia"},{"key":"R26-2-20210203","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1046\/j.1365-2516.2003.00783.x","article-title":"Economic modelling of different treatment strategies for haemophilia A with high-responding inhibitors","volume":"9","author":"Knight","year":"2003","journal-title":"Haemophilia"},{"key":"R27-2-20210203","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1111\/j.1365-2516.2004.00950.x","article-title":"Treatment patterns and cost-of-illness of severe haemophilia in patients with inhibitors in Germany","volume":"10","author":"Auerswald","year":"2004","journal-title":"Haemophilia"},{"issue":"2 Suppl 4","key":"R28-2-20210203","first-page":"62","article-title":"Immunetolerance as treatment of alloantibodies to factor VIII in hemophilia. The International Registry of Immunetolerance Protocols","volume":"31","author":"Mariani","year":"1994","journal-title":"Semin Hematol"},{"key":"R29-2-20210203","doi-asserted-by":"crossref","first-page":"983","DOI":"10.1182\/blood.V86.3.983.983","article-title":"Low-dose immune tolerance induction in hemophilia A patients with inhibitors","volume":"86","author":"Mauser-Bunschoten","year":"1995","journal-title":"Blood"},{"issue":"Suppl 3","key":"R30-2-20210203","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1046\/j.1365-2516.1999.00034.x","article-title":"Use of prothrombin complex concentrates and activated prothrombin complex concentrates as prophylactic therapy in haemophilia patients with inhibitors","volume":"5","author":"Leissinger","year":"1999","journal-title":"Haemophilia"},{"key":"R31-2-20210203","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1365-2516.2005.01096.x","article-title":"Prophylactic recombinant factor VIIa in haemophilia patients with inhibitors","volume":"11","author":"Young","year":"2005","journal-title":"Haemophilia"}],"container-title":["Blood Coagulation & Fibrinolysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/MBC.0b013e328313fc8e","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T17:27:34Z","timestamp":1786037254000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00001721-200901000-00002"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1]]},"references-count":29,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2009]]}},"URL":"https:\/\/doi.org\/10.1097\/mbc.0b013e328313fc8e","relation":{},"ISSN":["0957-5235"],"issn-type":[{"value":"0957-5235","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1]]}}}