{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,20]],"date-time":"2026-08-20T15:22:08Z","timestamp":1787239328207,"version":"build-2736575974"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>\n                    Limited objective data exist on the comparison of post-endoscopic retrograde cholangiopancreatography (ERCP) complications in patients with cirrhosis based on the severity of the disease. We evaluated the effectiveness of the Child-Turcotte-Pugh (CTP) score system in anticipating the risk of post-ERCP complications in patients with cirrhosis. The PubMed, Scopus, Embase, and Cochrane databases were searched from inception through September 2022 to identify studies comparing post-ERCP complications in patients with cirrhosis based on CTP score. Odds ratios (ORs) and their associated 95% CIs were pooled using a random-effect model to calculate effect size. The reference group for analysis was the CTP class C patient group. Seven studies comprising 821 patients who underwent 1068 ERCP procedures were included. The CTP class C patient population exhibited a higher risk of overall post-ERCP adverse events compared with those with class A or B (OR: 2.87, 95% CI: 1.77-4.65,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.00 and OR: 2.02, 95% CI: 1.17-3.51,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.01, respectively). Moreover, CTP class B patients had a significantly higher complication rate than CTP class A patients (OR: 1.62, 95% CI: 1.04-2.53,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    = 0.03). However, no statistically significant differences were found in the occurrence of specific types of complications, including bleeding, pancreatitis, cholangitis, perforation, or mortality across the three CTP groups. We demonstrated that the CTP classification system is a reliable predictor of ERCP complications in patients with cirrhosis. Consequently, caution should be exercised when performing ERCP in patients classified as CTP class C.\n                  <\/jats:p>","DOI":"10.1097\/mcg.0000000000002012","type":"journal-article","created":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T10:06:56Z","timestamp":1714471616000},"page":"554-563","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Applicability of Child-Turcotte-Pugh Score in Anticipating Post-ERCP Adverse Events in Patients With Cirrhosis"],"prefix":"10.1097","volume":"58","author":[{"given":"Saqr","family":"Alsakarneh","sequence":"first","affiliation":[{"name":"Department of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fouad","family":"Jaber","sequence":"additional","affiliation":[{"name":"Department of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willie","family":"Mohammed","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, University of Minnesota, Minneapolis, MN"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Almeqdadi","sequence":"additional","affiliation":[{"name":"Department of Medicine, Tufts University, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdallah","family":"Al-Ani","sequence":"additional","affiliation":[{"name":"Office of Scientific Affairs and Research, King Hussein Cancer Center, Amman, Jordan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yassine","family":"Kilani","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Lincoln Medical Center, NY"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeed","family":"Abughazaleh","sequence":"additional","affiliation":[{"name":"Department of Medicine, Tufts University, Boston, MA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laith","family":"Momani","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Missouri Kansas City, Kansas, MO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad Shah","family":"Miran","sequence":"additional","affiliation":[{"name":"Department of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Ghoz","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Missouri Kansas City, Kansas, MO"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John","family":"Helzberg","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, University of Missouri Kansas City, Kansas, 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