{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T08:40:33Z","timestamp":1777365633044,"version":"3.51.4"},"reference-count":42,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,1]]},"DOI":"10.1097\/mcg.0b013e3180653cb7","type":"journal-article","created":{"date-parts":[[2009,3,5]],"date-time":"2009-03-05T04:17:17Z","timestamp":1236226637000},"page":"29-35","source":"Crossref","is-referenced-by-count":28,"title":["Effects of Helicobacter pylori Infection on Gastric Mucin Expression"],"prefix":"10.1097","volume":"42","author":[{"given":"Hyung Min","family":"Kang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nayoung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Young Soo","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Hyeok","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin-Wook","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sook-Hyang","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong Ho","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hye Seung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun Chae","family":"Jung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In Sung","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-7-20210305","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1095\/biolreprod51.4.685","article-title":"Complementary deoxyribonucleic acid cloning and molecular characterization of an estrogen-dependent human oviductal glycoprotein","volume":"51","author":"Arias","year":"1994","journal-title":"Biol Reprod"},{"key":"R2-7-20210305","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1023\/A:1025815113599","article-title":"Mucins and mucin binding proteins in colorectal cancer","volume":"23","author":"Byrd","year":"2004","journal-title":"Cancer Metastasis Rev"},{"key":"R3-7-20210305","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1136\/gut.47.4.589","article-title":"Mucins and mucosal protection in the gastrointestinal tract: new prospects for mucins in the pathology of gastrointestinal disease","volume":"47","author":"Corfield","year":"2000","journal-title":"Gut"},{"key":"R4-7-20210305","first-page":"2681","article-title":"Mucin gene expression in normal, preneoplastic, and neoplastic human gastric epithelium","volume":"55","author":"Ho","year":"1995","journal-title":"Cancer Res"},{"key":"R5-7-20210305","first-page":"641","article-title":"Heterogeneity of mucin gene expression in normal and neoplastic tissues","volume":"53","author":"Ho","year":"1993","journal-title":"Cancer Res"},{"key":"R6-7-20210305","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1056\/NEJM199104113241507","article-title":"Helicobacter pylori and peptic ulcer disease","volume":"324","author":"Peterson","year":"1991","journal-title":"N Engl J Med"},{"key":"R7-7-20210305","doi-asserted-by":"crossref","first-page":"1127","DOI":"10.1056\/NEJM199110173251603","article-title":"Helicobacter pylori infection and the risk of gastric carcinoma","volume":"325","author":"Parsonnet","year":"1991","journal-title":"N Engl J Med"},{"key":"R8-7-20210305","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1056\/NEJM199803193381205","article-title":"Molecular analysis of the progression from Helicobacter pylori-associated chronic gastritis to mucosa-associated lymphoid-tissue lymphoma of the stomach","volume":"338","author":"Zucca","year":"1998","journal-title":"N Engl J Med"},{"key":"R9-7-20210305","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1093\/infdis\/153.4.658","article-title":"Campylobacter pyloridis and gastritis: association with intercellular spaces and adaptation to an environment of mucus as important factors in colonization of the gastric epithelium","volume":"153","author":"Hazell","year":"1986","journal-title":"J Infect Dis"},{"key":"R10-7-20210305","doi-asserted-by":"crossref","first-page":"2215","DOI":"10.1128\/JCM.38.6.2215-2218.2000","article-title":"Role of vacA and cagA in Helicobacter pylori inhibition of mucin synthesis in gastric mucous cells","volume":"38","author":"Beil","year":"2000","journal-title":"J Clin Microbiol"},{"key":"R11-7-20210305","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1053\/gast.1997.v113.pm9247464","article-title":"Aberrant expression of gland-type gastric mucin in the surface epithelium of Helicobacter pylori-infected patients","volume":"113","author":"Byrd","year":"1997","journal-title":"Gastroenterology"},{"key":"R12-7-20210305","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1016\/S0016-5085(00)70360-X","article-title":"Inhibition of gastric mucin synthesis by Helicobacter pylori","volume":"118","author":"Byrd","year":"2000","journal-title":"Gastroenterology"},{"key":"R13-7-20210305","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1097\/01.mcg.0000123168.86324.1b","article-title":"A confirmatory report for the close interaction of Helicobacter pylori with gastric epithelial MUC5AC expression","volume":"38","author":"Kocer","year":"2004","journal-title":"J Clin Gastroenterol"},{"key":"R14-7-20210305","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1111\/j.1523-5378.2003.00185.x","article-title":"Helicobacter pylori infection up-regulates gland mucous cell-type mucins in gastric pyloric mucosa","volume":"8","author":"Matsuzwa","year":"2003","journal-title":"Helicobacter"},{"key":"R15-7-20210305","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1097\/00042737-200101000-00004","article-title":"Does Helicobacter pylori affect gastric mucin expression? Relationship between gastric antral mucin statement and H. pylori colonization","volume":"13","author":"Morgenstern","year":"2001","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"R16-7-20210305","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1177\/002215540004800307","article-title":"Immunohistochemical study of the expression of MUC6 mucin and co-expression of other secreted mucins (MUC5AC and MUC2) in human gastric carcinomas","volume":"48","author":"Reis","year":"2000","journal-title":"J Histochem Cytochem"},{"key":"R17-7-20210305","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/(SICI)1097-0215(19970220)74:1<112::AID-IJC19>3.0.CO;2-H","article-title":"Immunohistochemical study of MUC5AC expression in human gastric carcinomas using a novel monoclonal antibody","volume":"74","author":"Reis","year":"1997","journal-title":"Int J Cancer"},{"key":"R18-7-20210305","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/0016-5085(95)90412-3","article-title":"Diversity of mucin genes, structure, function, and expression","volume":"109","author":"Kim","year":"1995","journal-title":"Gastroenterology"},{"key":"R19-7-20210305","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1126\/science.1099250","article-title":"Natural antibiotic function of a human gastric mucin against Helicobacter pylori infection","volume":"305","author":"Kawakubo","year":"2004","journal-title":"Science"},{"key":"R20-7-20210305","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/path.1711650111","article-title":"Helicobacter pylori in gastric biopsy specimens. Comparison of culture, modified Giemsa stain, and immunohistochemistry. A retrospective study","volume":"165","author":"Loffeld","year":"1991","journal-title":"J Pathol"},{"key":"R21-7-20210305","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1097\/00004836-200609000-00004","article-title":"Institutional difference of antibiotic resistance of Helicobacter pylori strains in Korea","volume":"40","author":"Kim","year":"2006","journal-title":"J Clin Gastroenterol"},{"key":"R22-7-20210305","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0046-8177(94)90191-0","article-title":"Simultaneous visualization of Helicobacter pylori and gastric morphology: a new stain","volume":"25","author":"Genta","year":"1994","journal-title":"Hum Pathol"},{"key":"R23-7-20210305","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1097\/00000478-199610000-00001","article-title":"Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994","volume":"20","author":"Dixon","year":"1996","journal-title":"Am J Surg Pathol"},{"key":"R24-7-20210305","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1080\/01971529808005485","article-title":"Serodiagnosis of Helicobacter pylori infection in Korean patients using enzyme-linked immunosorbent assay","volume":"19","author":"Kim","year":"1998","journal-title":"J Immunoassay"},{"key":"R25-7-20210305","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1046\/j.1440-1746.2001.02568.x","article-title":"Korean H. pylori Study Group, South Korea. Seroepidemiological study of Helicobacter pylori infection in asymptomatic people in South Korea","volume":"16","author":"Kim","year":"2001","journal-title":"J Gastroenterol Hepatol"},{"key":"R26-7-20210305","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1023\/A:1006939432665","article-title":"Development and characterization of an antibody directed to an alpha-N-acetyl-D-galactosamine glycosylated MUC2 peptide","volume":"15","author":"Reis","year":"1998","journal-title":"Glycoconj J"},{"key":"R27-7-20210305","doi-asserted-by":"crossref","first-page":"1479","DOI":"10.1177\/41.10.8245407","article-title":"Expression of human mucin genes in respiratory, digestive, and reproductive tracts ascertained by in situ hybridization","volume":"41","author":"Audie","year":"1993","journal-title":"J Histochem Cytochem"},{"key":"R28-7-20210305","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1177\/002215540004801209","article-title":"Developmental mucin gene expression in the gastroduodenal tract and accessory digestive glands. I. Stomach. A relationship to gastric carcinoma","volume":"48","author":"Buisine","year":"2000","journal-title":"J Histochem Cytochem"},{"key":"R29-7-20210305","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1002\/(SICI)1096-9896(199812)186:4<398::AID-PATH192>3.0.CO;2-X","article-title":"The MUC6 secretory mucin gene is expressed in a wide variety of epithelial tissues","volume":"186","author":"Bartman","year":"1998","journal-title":"J Pathol"},{"key":"R30-7-20210305","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1016\/0016-5085(95)90379-8","article-title":"MUC6 apomucin shows a distinct normal tissue distribution that correlates with Lewis antigen expression in the human stomach","volume":"109","author":"De Bolos","year":"1995","journal-title":"Gastroenterology"},{"key":"R31-7-20210305","doi-asserted-by":"crossref","first-page":"1183","DOI":"10.1097\/00042737-200411000-00017","article-title":"Histological changes in the gastric mucosa after Helicobacter pylori eradication","volume":"16","author":"Fichman","year":"2004","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"R32-7-20210305","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1196\/annals.1299.014","article-title":"The effect of p38 mitogen-activated protein kinase on mucin gene expression and apoptosis in Helicobacter pylori-infected gastric epithelial cells","volume":"1010","author":"Kim","year":"2003","journal-title":"Ann N Y Acad Sci"},{"key":"R33-7-20210305","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.prp.2005.03.007","article-title":"Topographic expression of MUC5AC and MUC6 in the gastric mucosa infected by Helicobacter pylori and in associated diseases","volume":"201","author":"Marques","year":"2005","journal-title":"Pathol Res Pract"},{"key":"R34-7-20210305","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1007\/s10620-005-2708-4","article-title":"Infection with Helicobacter pylori affects all major secretory cell populations in the human antrum","volume":"50","author":"Van De Bovenkamp","year":"2005","journal-title":"Dig Dis Sci"},{"key":"R35-7-20210305","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1136\/gut.46.5.601","article-title":"H pylori colocalises with MUC5AC in the human stomach","volume":"46","author":"Van den Brink","year":"2000","journal-title":"Gut"},{"key":"R36-7-20210305","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S0006-291X(02)00463-1","article-title":"Disruption in gastric mucin synthesis by Helicobacter pylori lipopolysaccharide involves ERK and p38 mitogen-activated protein kinase participation","volume":"294","author":"Slomiany","year":"2002","journal-title":"Biochem Biophys Res Commun"},{"key":"R37-7-20210305","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1007\/s004280050269","article-title":"Helicobacter pylori infection produces reversible glycosylation changes to gastric mucins","volume":"433","author":"Ota","year":"1998","journal-title":"Virchows Arch"},{"key":"R38-7-20210305","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1046\/j.1523-5378.2003.00173.x","article-title":"The MUC5AC glycoprotein is the primary receptor for Helicobacter pylori in the human stomach","volume":"8","author":"Van de Bovenkamp","year":"2003","journal-title":"Helicobacter"},{"key":"R39-7-20210305","doi-asserted-by":"crossref","first-page":"817","DOI":"10.1007\/s00432-006-0135-3","article-title":"MUC6 down-regulation correlates with gastric carcinoma progression and a poor prognosis: an immunohistochemical study with tissue microarrays","volume":"132","author":"Zheng","year":"2006","journal-title":"J Cancer Res Clin Oncol"},{"key":"R40-7-20210305","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1476-4598-5-10","article-title":"Expression profile of mucins (MUC2, MUC5AC and MUC6) in Helicobacter pylori infected pre-neoplastic and neoplastic human gastric epithelium","volume":"5","author":"Babu","year":"2006","journal-title":"Mol cancer"},{"key":"R41-7-20210305","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1023\/B:DDAS.0000034554.96191.66","article-title":"Prognostic significance of mucin expression in gastric carcinoma","volume":"49","author":"Kocer","year":"2004","journal-title":"Dig Dis Sci"},{"key":"R42-7-20210305","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1111\/j.1440-1746.2005.04006.x","article-title":"Effects of Helicobacter pylori infection on mucin expression in gastric carcinoma and pericancerous tissues","volume":"21","author":"Wang","year":"2006","journal-title":"J Gastroenterol Hepatol"}],"container-title":["Journal of Clinical Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.lww.com\/00004836-200801000-00007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,10]],"date-time":"2021-04-10T06:19:42Z","timestamp":1618035582000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00004836-200801000-00007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,1]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.1097\/mcg.0b013e3180653cb7","relation":{},"ISSN":["0192-0790"],"issn-type":[{"value":"0192-0790","type":"print"}],"subject":[],"published":{"date-parts":[[2008,1]]}}}