{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T08:48:33Z","timestamp":1694767713884},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Rationale:<\/jats:title>\n            <jats:p>Bronchoscopic cryotherapy has been considered as one of the optional interventions for unresectable malignant central airway obstruction (CAO). And it provides high safety and effectiveness in airway patency re-establishment. This report describes the interventional bronchoscopic cryotherapy for a patient with CAO caused by squamous cell carcinoma of the esophagus. We display a series of dramatic change of chest radiographs before and after the intervention.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Patient concerns:<\/jats:title>\n            <jats:p>A 70-year-old man with squamous cell carcinoma of the middle third of the esophagus (initial staging, pT2N0M0; stage IIB; in January 2017) underwent Video-assisted esophagectomy and reconstruction with a gastric conduit via a substernal route. Following Chest computed tomography and positron emission tomography revealed disease progression with paratracheal metastases. Progressive dyspnea and chest pain lasted for a month, and he was admitted to the ER.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Diagnoses:<\/jats:title>\n            <jats:p>Blood gas analysis revealed type I respiratory failure (pH, 7.445; PaO2, 69.4 mmHg; PaCO2, 40.6 mmHg). Other laboratory data were grossly normal. Chest radiography revealed a total left lung collapse. Chest CT identified a tumor blocking the left mainstem bronchus with the consolidation of the left lung.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Interventions:<\/jats:title>\n            <jats:p>Dexamethasone and epinephrine inhalation were administered for initial symptom relief. Bronchoscopy performed 4 days after admission revealed a huge tumor completely occluding the left mainstem bronchus orifice. The occlusion was completely resolved following cryotherapy. Then, the first course of palliative chemotherapy with cisplatin plus fluorouracil, followed by the second course a month later, was administered.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Outcomes:<\/jats:title>\n            <jats:p>The latest chest radiograph showed a patent airway. The patient's condition remained stable for at least the following 2 months.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Lessons:<\/jats:title>\n            <jats:p>Malignant CAO is a rare but potentially life-threatening condition. Several acceptable bronchoscopy techniques exist for treatment. Cryotherapy has high safety and effectiveness in airway patency re-establishment.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/md.0000000000014635","type":"journal-article","created":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T20:42:28Z","timestamp":1551386548000},"page":"e14635","source":"Crossref","is-referenced-by-count":1,"title":["Bronchoscopic cryosurgery for metastatic tumor causing central airway obstruction"],"prefix":"10.1097","volume":"98","author":[{"given":"Tun-Yi","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung"},{"name":"School of Medicine, National Yang-Ming University, Taipei"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yih-Gang","family":"Goan","sequence":"additional","affiliation":[{"name":"School of Medicine, National Yang-Ming University, Taipei"},{"name":"Division of Thoracic Surgery, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"En-Kuei","family":"Tang","sequence":"additional","affiliation":[{"name":"School of Medicine, National Yang-Ming University, Taipei"},{"name":"Division of Thoracic Surgery, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yen-Chiang","family":"Tseng","sequence":"additional","affiliation":[{"name":"School of Medicine, National Yang-Ming University, Taipei"},{"name":"Division of Thoracic Surgery, Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung"},{"name":"Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"issue":"(suppl 4)","key":"R1-20230914","first-page":"S363","article-title":"From electrocautery, balloon dilatation, neodymiumdoped: yttrium-aluminum-garnet (Nd:YAG) laser to argon plasma coagulation and cryotherapy","volume":"7","author":"Ashutosh","year":"2015","journal-title":"J Thorac Dis"},{"key":"R2-20230914","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1111\/1759-7714.12337","article-title":"Fibrobronchoscopic cryosurgery for secondary malignant tumors of the trachea and main bronchi","volume":"7","author":"Qianli","year":"2016","journal-title":"Thorac Cancer"},{"key":"R3-20230914","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1183\/09031936.06.00014006","article-title":"Place of cryotherapy, brachytherapy and photodynamic therapy in therapeutic bronchoscopy of lung cancers","volume":"28","author":"Vergnon","year":"2006","journal-title":"Eur Respir J"},{"key":"R4-20230914","doi-asserted-by":"crossref","first-page":"2619","DOI":"10.21037\/jtd.2017.07.68","article-title":"The technique of endoscopic airway tumor treatment","volume":"9","author":"Simone","year":"2017","journal-title":"J Thorac Dis"},{"key":"R5-20230914","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1164\/rccm.200210-1181SO","article-title":"Central airway obstruction","volume":"169","author":"Ernst","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"R6-20230914","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1164\/rccm.200210-1181SO","article-title":"Central airway obstruction: benign strictures, tracheobronchomalacia, and malignancy-related obstruction","volume":"169","author":"Murgu","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"R7-20230914","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1016\/j.arbres.2013.12.012","article-title":"Non-malignant central airway obstruction","volume":"50","author":"Barros Casas","year":"2014","journal-title":"Arch Bronconeumol"},{"issue":"(suppl 10)","key":"R8-20230914","first-page":"S1087","article-title":"Malignant central airway obstruction","volume":"9","author":"Lakshmi","year":"2017","journal-title":"J Thorac Dis"},{"key":"R9-20230914","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1111\/1759-7714.12248","article-title":"Bronchoscopic debulking for endobronchial malignancy: predictors of recanalization and recurrence","volume":"6","author":"Kuo","year":"2015","journal-title":"Thorac Cancer"},{"key":"R10-20230914","doi-asserted-by":"crossref","first-page":"263","DOI":"10.1053\/j.semtcvs.2009.08.002","article-title":"Endoscopic management of central airway obstruction","volume":"21","author":"Gorden","year":"2009","journal-title":"Semin Thorac Cardiovasc Surg"}],"container-title":["Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/00005792-201903010-00021","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,14]],"date-time":"2023-09-14T18:34:14Z","timestamp":1694716454000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00005792-201903010-00021"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":10,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.1097\/md.0000000000014635","relation":{},"ISSN":["0025-7974","1536-5964"],"issn-type":[{"value":"0025-7974","type":"print"},{"value":"1536-5964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3]]}}}