{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,13]],"date-time":"2026-07-13T12:57:12Z","timestamp":1783947432637,"version":"3.55.0"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"12","license":[{"start":{"date-parts":[[2020,3,1]],"date-time":"2020-03-01T00:00:00Z","timestamp":1583020800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"funder":[{"DOI":"10.13039\/501100012151","name":"Sanming Project of Medicine in Shenzhen","doi-asserted-by":"crossref","award":["SZSM201512043"],"award-info":[{"award-number":["SZSM201512043"]}],"id":[{"id":"10.13039\/501100012151","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"abstract":"<jats:title>Abstract<\/jats:title>\n          <jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Diabetic foot (DF) problems are common throughout the world, about one-fourth of them develop a foot ulcer and serious cases would suffer from amputation, which seriously affects the patient's work and life. Previous studies indicated that acupuncture as adjuvant therapy would be effective in treating DF. However, these studies have no consistent results. Therefore, the aim of our study was to explore the efficacy and safety of acupuncture as adjuvant therapy for DF.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>The randomized controlled trials associated with acupuncture therapy (or as adjuvant therapy) for DF will be included. We will search 6 electronic databases relevant to health sciences, including PubMed, Embase, the Cochrane Library, the Chinese databases Sino-Med, CNKI, and WANFANG database. All searches were from databases inception to March 30, 2019. The primary outcomes are the total curative effective rate, and the hemodynamic parameter and adverse events will be deemed as secondary outcomes. The Stata15.1 software and Review Manager (RevMan 5.3; Cochrane Collaboration, Copenhagen, Denmark) will be used for analysis, to assess the bias risk, subgroup analysis, and data synthesis.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>In this systematic review and meta-analysis, we will synthesize the studies to assess the safety and efficacy of acupuncture as adjuvant therapy for DF.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>The summary of our study will clarify whether acupuncture as adjuvant therapy could be an efficient method for DF.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/md.0000000000019502","type":"journal-article","created":{"date-parts":[[2020,3,20]],"date-time":"2020-03-20T10:11:28Z","timestamp":1584699088000},"page":"e19502","source":"Crossref","is-referenced-by-count":5,"title":["Acupuncture as adjuvant therapy for diabetic foot"],"prefix":"10.1097","volume":"99","author":[{"given":"Maosheng","family":"Lee","sequence":"first","affiliation":[{"name":"Guangzhou University of Chinese Medicine, University Town of Guangzhou, Panyu District, Guangzhou City"},{"name":"Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Futian District, Shenzhen City, Guangdong Province, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huilin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Futian District, Shenzhen City, Guangdong Province, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deliang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Shenzhen Traditional Chinese Medicine Hospital, Futian District, Shenzhen City, Guangdong Province, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2020,3]]},"reference":[{"key":"R1-20230915","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1001\/jama.293.2.217","article-title":"Preventing foot ulcers in patients with diabetes","volume":"293","author":"Singh","year":"2005","journal-title":"JAMA"},{"key":"R2-20230915","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1111\/j.1464-5491.2010.02989.x","article-title":"A systematic review of scoring systems for diabetic foot ulcers","volume":"27","author":"Karthikesalingam","year":"2010","journal-title":"Diabet Med"},{"key":"R3-20230915","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1007\/s11892-005-0051-y","article-title":"The International Diabetes Federation focuses on the diabetic foot","volume":"5","author":"Bakker","year":"2005","journal-title":"Curr Diab Rep"},{"key":"R4-20230915","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/S0140-6736(05)66437-9","article-title":"World Diabetes Day: footing the bill","volume":"365","author":"Jeffcoate","year":"2005","journal-title":"Lancet"},{"key":"R5-20230915","doi-asserted-by":"crossref","first-page":"2305","DOI":"10.2337\/diacare.26.8.2305","article-title":"Predicted costs and outcomes from reduced vibration detection in people with diabetes in the US","volume":"26","author":"Shearer","year":"2003","journal-title":"Diabetes Care"},{"key":"R6-20230915","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.2337\/diacare.26.6.1790","article-title":"The health care costs of diabetic peripheral neuropathy in the US","volume":"26","author":"Gordois","year":"2003","journal-title":"Diabetes Care"},{"key":"R7-20230915","doi-asserted-by":"crossref","first-page":"1","DOI":"10.4196\/kjpp.2014.18.1.1","article-title":"Advanced glycation end products and diabetic complications","volume":"18","author":"Singh","year":"2014","journal-title":"Korean J Physiol Pharmacol"},{"key":"R8-20230915","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1136\/bmj.303.6809.1053","article-title":"ABC of vascular diseases. The diabetic foot","volume":"303","author":"Elkeles","year":"1991","journal-title":"BMJ"},{"key":"R9-20230915","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1007\/s00125-004-1463-y","article-title":"The diabetic foot: from art to science. The 18th Camillo Golgi lecture","volume":"47","author":"Boulton","year":"2004","journal-title":"Diabetologia"},{"key":"R11-20230915","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/dmrr.2249","article-title":"A systematic review of the effectiveness of revascularization of the ulcerated foot in patients with diabetes and peripheral arterial disease","volume":"28","author":"Hinchliffe","year":"2012","journal-title":"Diabetes Metab Res Rev"},{"key":"R12-20230915","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/S0168-8227(97)00123-X","article-title":"Acupuncture for the treatment of chronic painful peripheral diabetic neuropathy: a long-term study","volume":"39","author":"Abuaisha","year":"1998","journal-title":"Diabetes Res Clin Pract"},{"key":"R13-20230915","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.jams.2016.10.004","article-title":"Acupuncture treatment of diabetic peripheral neuropathy in an American Indian community","volume":"10","author":"Bailey","year":"2017","journal-title":"J Acupunct Meridian Stud"},{"key":"R14-20230915","first-page":"468","article-title":"Wet blood stasis syndrome treated with acupuncture combined with traditional Chinese medicine fumigating and washing with diabetic foot disease","volume":"38","author":"He","year":"2018","journal-title":"Jilin J Chin Med"},{"key":"R15-20230915","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/2046-4053-4-1","article-title":"Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement","volume":"4","author":"Moher","year":"2015","journal-title":"Syst Rev"},{"key":"R16-20230915","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1371\/journal.pmed.1000100","article-title":"The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration","volume":"6","author":"Liberati","year":"2009","journal-title":"PLoS Med"},{"key":"R18-20230915","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/j.jclinepi.2010.07.015","article-title":"GRADE guidelines: 3. Rating the quality of evidence","volume":"64","author":"Balshem","year":"2011","journal-title":"J Clin Epidemiol"},{"key":"R19-20230915","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1007\/BF00253862","article-title":"Blood flow in the diabetic neuropathic foot","volume":"22","author":"Edmonds","year":"1982","journal-title":"Diabetologia"}],"container-title":["Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/MD.0000000000019502","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,15]],"date-time":"2023-09-15T22:20:06Z","timestamp":1694816406000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/MD.0000000000019502"}},"subtitle":["A protocol for systematic review"],"short-title":[],"issued":{"date-parts":[[2020,3]]},"references-count":17,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.1097\/md.0000000000019502","relation":{},"ISSN":["0025-7974","1536-5964"],"issn-type":[{"value":"0025-7974","type":"print"},{"value":"1536-5964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,3]]}}}