{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T03:56:56Z","timestamp":1769313416788,"version":"3.49.0"},"reference-count":23,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"20","license":[{"start":{"date-parts":[[2021,5,21]],"date-time":"2021-05-21T00:00:00Z","timestamp":1621555200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n            <jats:title>Abstract<\/jats:title>\n            <jats:p>There might be a thick \u201cprotrusion\u201d in the visceral surface of hepatic quadrate lobe during the laparoscopic cholecystectomy (LC), which affects the surgical fields and consequently triggers high risks of biliary tract injury. Although n-butyl-2-cyanoacrylate (NBCA) glue has been applied to laparoscopic upper abdominal surgery for liver retraction, there is still no consensus on its safety and feasibility in LC. In this study, we investigated the safety, feasibility, and effectiveness of liver retraction using NBCA glue for these patients which have the thick \u201cprotrusion\u201d on the square leaf surface of the liver during LC.<\/jats:p>\n            <jats:p>Fifty-seven patients presenting thick \u201cprotrusion\u201d hepatic quadrate lobe were included in our retrospective study. We performed LC in the presence of NBCA glue (n\u200a=\u200a30, NBCA group) and absence of NBCA glue (n\u200a=\u200a27, non-NBCA group), respectively. NBCA was used to fix the thick \u201cprotrusion\u201d of the liver leaves to the hepatic viscera surface, which contributed to the revelation of the gallbladder triangle. The operation time, blood loss, postoperative hospitalization, and liver function were compared between the 2 groups.<\/jats:p>\n            <jats:p>Both the groups\u2019 patients accomplished the operation in the laparoscopy. There was no mortality and no additional incision during operation. No severe complications including bile duct injury were available after surgery and no postoperative NBCA-related complications occurred after 9- to 30\u200amonths\u2019 follow-up. The time of operation in NBCA group showed significant decrease compared with that of non-NBCA group (48.33\u200a\u00b1\u200a16.15 vs 65.00\u200a\u00b1\u200a22.15\u200aminutes, <jats:italic toggle=\"yes\">P<\/jats:italic>\u200a&lt;\u200a.01). There were no significant differences in blood loss, postoperative hospital stays, and the preoperative and postoperative liver function between the two groups (<jats:italic toggle=\"yes\">P<\/jats:italic>\u200a&gt;\u200a.05). Besides, no significant differences were noticed in major clinical characteristics between the 2 groups (<jats:italic toggle=\"yes\">P<\/jats:italic>\u200a&gt;\u200a.05).<\/jats:p>\n            <jats:p>Liver retraction using NBCA during LC for thick \u201cprotrusion\u201d hepatic quadrate lobe patients is safe, effective, and feasible.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/md.0000000000025879","type":"journal-article","created":{"date-parts":[[2021,5,18]],"date-time":"2021-05-18T15:00:06Z","timestamp":1621350006000},"page":"e25879","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Liver retraction using n-butyl-2-cyanoacrylate glue during laparoscopic cholecystectomy"],"prefix":"10.1097","volume":"100","author":[{"given":"Gang","family":"Du","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Du","family":"Kong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Binyao","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhengchen","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muguo","family":"Aniu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinhuan","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Gao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bin","family":"Jin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2021,5,21]]},"reference":[{"key":"R1-20250504","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1089\/lap.2013.0485","article-title":"A new technique for liver retraction during single-port laparoscopic surgery","volume":"24","author":"Surjan","year":"2014","journal-title":"J Laparoendosc Adv Surg Tech A"},{"key":"R2-20250504","doi-asserted-by":"crossref","first-page":"228","DOI":"10.4293\/108680810X12785289144278","article-title":"Single-incision sleeve gastrectomy using a novel technique for liver retraction","volume":"14","author":"Galvani","year":"2010","journal-title":"JSLS"},{"key":"R3-20250504","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1007\/s11695-011-0383-4","article-title":"Veress needle: a simple liver retraction technique for lap band positioning in (single incision laparoscopic technique) SILS","volume":"22","author":"Gianni","year":"2012","journal-title":"Obes Surg"},{"key":"R4-20250504","doi-asserted-by":"crossref","first-page":"e99","DOI":"10.1097\/SLE.0b013e3181e13568","article-title":"Single-incision transumbilical laparoscopic adjustable gastric banding: a novel minimally invasive surgical technique","volume":"20","author":"Huang","year":"2010","journal-title":"Surg Laparosc Endosc Percutan Tech"},{"key":"R5-20250504","doi-asserted-by":"crossref","first-page":"1707","DOI":"10.1007\/s11695-009-9896-5","article-title":"Transumbilical single-port laparoscopic adjustable gastric band placement with liver suture retractor","volume":"19","author":"de la Torre","year":"2009","journal-title":"Obes Surg"},{"key":"R6-20250504","doi-asserted-by":"crossref","first-page":"3064046","DOI":"10.1155\/2018\/3064046","article-title":"Liver retraction using n-Butyl-2-Cyanoacrylate (NBCA) glue during laparoscopic splenectomy and azygoportal disconnection in cirrhotic patients","volume":"2018","author":"Kong","year":"2018","journal-title":"Biomed Res Int"},{"key":"R7-20250504","doi-asserted-by":"crossref","first-page":"198","DOI":"10.4103\/0972-9941.140202","article-title":"Review of various liver retraction techniques in single incision laparoscopic surgery for the exposure of hiatus","volume":"11","author":"Palanivelu","year":"2015","journal-title":"J Minim Access Surg"},{"key":"R8-20250504","doi-asserted-by":"crossref","first-page":"1295","DOI":"10.1016\/j.suc.2008.07.005","article-title":"Laparoscopic cholecystectomy","volume":"88","author":"Litwin","year":"2008","journal-title":"Surg Clin North Am"},{"key":"R9-20250504","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1001\/archsurg.1990.01410220029002","article-title":"Laparoscopic cholecystectomy. 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