{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T06:25:42Z","timestamp":1763706342953,"version":"3.40.5"},"reference-count":22,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"30","license":[{"start":{"date-parts":[[2022,7,29]],"date-time":"2022-07-29T00:00:00Z","timestamp":1659052800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:sec>\n            <jats:title>Rationale:<\/jats:title>\n            <jats:p>IgG4-related respiratory disease (IgG4-RRD) is a chronic autoimmune disease that affects the respiratory system and organs outside the respiratory system. This study explored the diagnosis and treatment of a case of IgG4-RRD with unilateral pleural effusion diagnosed using medical thoracoscopy, and provides an associated literature review. This report summarizes the clinical characteristics of IgG4-RRD involving the pleura to improve the diagnosis of this disease.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Patient concerns:<\/jats:title>\n            <jats:p>A 39-year-old man presented with a 2-week history of cough and chest tightness. Both physical examination and imaging supported the presence of left pleural effusion.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Diagnosis:<\/jats:title>\n            <jats:p>Medical electronic thoracoscopy was performed to obtain a pleural biopsy, which showed lymphoplasmacytic infiltration, 40 IgG4+ plasma cells per High Power Field (HPF) on microscopy, IgG4\/IgG ratio &gt;50%, phlebitis obliterans, and storiform fibrosis. The final diagnosis was IgG4-RRD.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Interventions and outcomes:<\/jats:title>\n            <jats:p>The patient was treated with methylprednisolone, after which his symptoms improved, and he was discharged. Oral hormone therapy was continued outside the hospital. After 4 months, the patient returned to the hospital and his condition had improved significantly.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Lessons:<\/jats:title>\n            <jats:p>Pleural involvement in IgG4-RRD is rare, and its diagnosis depends on pleural biopsy. Thoracoscopy usually reveals pleural thickening, pleural nodules, and milky white plaques.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/md.0000000000029338","type":"journal-article","created":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T22:03:39Z","timestamp":1660169019000},"page":"e29338","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["A case report of IgG4-related respiratory disease with pleural effusion and a literature review"],"prefix":"10.1097","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6649-0941","authenticated-orcid":false,"given":"Qing","family":"Guo","sequence":"first","affiliation":[{"name":"College of Clinical Medicine, Jining Medical University, Jining, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yue","family":"Ren","sequence":"additional","affiliation":[{"name":"College of Clinical Medicine, Jining Medical University, Jining, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Quanyi","family":"Wang","sequence":"additional","affiliation":[{"name":"Pathology Department, Affiliated Hospital of Jining Medical University, Jining, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyun","family":"Pei","sequence":"additional","affiliation":[{"name":"College of Clinical Medicine, Jining Medical University, Jining, Shandong, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2583-8147","authenticated-orcid":false,"given":"Shenghua","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Affiliated Hospital of Jining Medical University, Jining, Shandong, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","published-online":{"date-parts":[[2022,7,29]]},"reference":[{"key":"R1-20250504","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.resinv.2015.09.002","article-title":"Proposed diagnostic criteria for IgG4-related respiratory disease.","volume":"54","author":"Matsui","year":"2016","journal-title":"Respir Investig"},{"key":"R2-20250504","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1007\/s00296-020-04555-y","article-title":"IgG4-related pleural disease with aortitis and submandibular glands involvement successfully treated with corticosteroid: case-based review.","volume":"40","author":"Okamoto","year":"2020","journal-title":"Rheumatol Int"},{"key":"R3-20250504","first-page":"101066","article-title":"IgG4-related disease with elevated adenosine deaminase in pleural effusion diagnosed clinically using thoracoscopy under local anesthesia and 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