{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T07:16:55Z","timestamp":1791357415397,"version":"4.3.1"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"32","license":[{"start":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T00:00:00Z","timestamp":1660262400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,8,12]]},"abstract":"<jats:p>Lumbar radiculopathy can be presented as low back pain and radiating pain. Transforaminal epidural steroid injection (TFESI) has been used to treat radicular pain, and after the injection, additional medications such as gabapentinoids including pregabalin (PGB) and gabapentin (GBP) can be administered to relieve remnant pain. However, little is known about the effectiveness of gabapentinoids in relieving pain after transforaminal epidural steroid injection.<\/jats:p>\n          <jats:p>This study was conducted to compare the effect of pregabalin and gabapentin in lumbar radiculopathy patients who underwent transforaminal epidural steroid injection.<\/jats:p>\n          <jats:p>One hundred seven patients who received TFESI and had taken PGB or GBP after the intervention at Daegu Catholic University Medical Center from January 2013 to August 2021 were included in this study. Visual Analogue Scale (VAS) was evaluated in all patients.<\/jats:p>\n          <jats:p>Among 107 patients, 57 (53.3%) patients took PGB and 50 (46.7%) patients took GBP after TFESI. The PGB and GBP groups showed reduced VAS scores according to visit (<jats:italic toggle=\"yes\">P<\/jats:italic> &lt; .001). However, no statistically signific<jats:italic toggle=\"yes\">a<\/jats:italic>nt differences in VAS scores according to the types of medication (<jats:italic toggle=\"yes\">P<\/jats:italic> = .811) and change aspects according to visit were observed between the PGB and GBP groups (<jats:italic toggle=\"yes\">P<\/jats:italic> = .947).<\/jats:p>\n          <jats:p>The study findings suggest that both pregabalin and gabapentin can be equally used to reduce pain in lumbar radiculopathy patients who underwent TFESI. Further studies with larger sample size are needed to generalize the findings of this study.<\/jats:p>","DOI":"10.1097\/md.0000000000029370","type":"journal-article","created":{"date-parts":[[2022,8,12]],"date-time":"2022-08-12T14:07:59Z","timestamp":1660313279000},"page":"e29370","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Comparing the therapeutic effects of pregabalin and gabapentin after transforaminal epidural nerve block in lumbar radiculopathy"],"prefix":"10.1097","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4969-3886","authenticated-orcid":false,"given":"Do Yun","family":"Kwon","sequence":"first","affiliation":[{"name":"Department of Physical Medicine and Rehabilitation, Daegu Catholic University Medical Center, Daegu, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Gyu","family":"Kwak","sequence":"additional","affiliation":[{"name":"Department of Medical Statistics, Daegu Catholic University School of Medicine, Daegu, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Hyuck","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, Daegu Catholic University Medical Center, Daegu, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250504","article-title":"A review of lumbar radiculopathy, diagnosis, and treatment.","volume":"11","author":"Berry","year":"2019","journal-title":"Cureus"},{"key":"R2-20250504","doi-asserted-by":"crossref","DOI":"10.1002\/14651858.CD013577","article-title":"Epidural corticosteroid injections for lumbosacral radicular pain.","author":"Oliveira","year":"2020","journal-title":"Cochrane Database Syst 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