{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T18:24:23Z","timestamp":1793384663619,"version":"4.5.0"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"51","license":[{"start":{"date-parts":[[2022,12,23]],"date-time":"2022-12-23T00:00:00Z","timestamp":1671753600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,12,23]]},"abstract":"<jats:sec>\n            <jats:title>Background:<\/jats:title>\n            <jats:p>Some studies have reported using ultrasonic evaluations to assess diaphragm function in patients with chronic obstructive pulmonary disease (COPD). However, they have limitations and thus cannot provide strong evidence to support ultrasound evaluations for diaphragm function and dysfunction severity assessments in this patient population. Additionally, quantitative studies on the relationship between ultrasound evaluations and diaphragm function do not exist. Therefore, we performed a systematic review and meta-analysis to explore the usefulness of ultrasonography for evaluating diaphragm function in patients with COPD.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Methods:<\/jats:title>\n            <jats:p>The Cochrane Library, PubMed, Embase, Web of Science, Chinese Biomedical Literature Database, Wanfang Data, China National Knowledge Network, and Chinese Scientific Journal Database (i.e., VIP) databases were searched for literature about ultrasonic evaluations of diaphragm function in patients with COPD for systematic review. We extracted patient demographic, diaphragm mobility, diaphragm thickness, diaphragm thickening score, and other related parameter data using RevMan 5.3 software for the meta-analysis.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Results:<\/jats:title>\n            <jats:p>We included 13 articles in the systematic review, 8 of which (494 participants) were included in the meta-analysis. The degree of diaphragm offset in patients with COPD was significantly lower than that in healthy controls (weighted mean difference [WMD]\u2005=\u2005\u20131.34; 95% confidence interval [CI]: \u20132.15, 0.53; <jats:italic toggle=\"yes\">P\u2005&lt;\u2005<\/jats:italic>.05). The diaphragm deviation was lower in the severe COPD group than in the mild-to-moderate COPD group (WMD\u2005=\u20050.50; 95% CI: \u20130.01, 1.01; <jats:italic toggle=\"yes\">P\u2005=\u2005<\/jats:italic>.06), but the difference was not significant.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Conclusion:<\/jats:title>\n            <jats:p>Ultrasonography effectively evaluates diaphragm function in patients with COPD. The diaphragm offset can be used as an auxiliary diagnostic index for COPD, which is also related to disease severity.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/md.0000000000032560","type":"journal-article","created":{"date-parts":[[2022,12,27]],"date-time":"2022-12-27T14:04:09Z","timestamp":1672149849000},"page":"e32560","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":15,"title":["Ultrasonographic evaluation of diaphragm function in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis"],"prefix":"10.1097","volume":"101","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5250-4890","authenticated-orcid":false,"given":"Zeng","family":"Hua-Rong","sequence":"first","affiliation":[{"name":"The First College of Clinical Medical Science, China Three Gorges University & Ultrasound Department of Yichang Central People\u2019s Hospital, Yichang, Hubei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Liang","sequence":"additional","affiliation":[{"name":"Yichang Maternal and Child Health Hospital, Yichang, Hubei, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu","family":"Rong","sequence":"additional","affiliation":[{"name":"The First College of Clinical Medical Science, China Three Gorges University & Ultrasound Department of Yichang Central People\u2019s Hospital, Yichang, Hubei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tu","family":"Yi-Fan","sequence":"additional","affiliation":[{"name":"The First College of Clinical Medical Science, China Three Gorges University & Ultrasound Department of Yichang Central People\u2019s Hospital, Yichang, Hubei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shi","family":"Dou-Zi","sequence":"additional","affiliation":[{"name":"The First College of Clinical Medical Science, China Three Gorges University & Ultrasound Department of Yichang Central People\u2019s Hospital, Yichang, Hubei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chen","family":"Yue","sequence":"additional","affiliation":[{"name":"The First College of Clinical Medical Science, China Three Gorges University & Ultrasound Department of Yichang Central People\u2019s Hospital, Yichang, Hubei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liu","family":"Zu-Lin","sequence":"additional","affiliation":[{"name":"The First College of Clinical Medical Science, China Three Gorges University & Ultrasound Department of Yichang Central People\u2019s Hospital, Yichang, Hubei, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20250504","doi-asserted-by":"crossref","first-page":"020415","DOI":"10.7189\/jogh.05.020415","article-title":"Global and regional estimates of COPD prevalence: systematic review and 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