{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T23:42:45Z","timestamp":1787010165621,"version":"build-2736575974"},"reference-count":61,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"42","license":[{"start":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T00:00:00Z","timestamp":1697760000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,10,20]]},"abstract":"<jats:p>\n                    The spectrum of major and minor salivary gland disorders varies widely. Epidemiological data on some injury categories are rare and often not up-to-date. This study aims to analyze epidemiological data using clinical, paraclinical, and histopathological parameters. Study was carried out for 5 years on the nonneoplastic and tumoral pathology of the salivary glands. Data were statistically analyzed using the appropriate parameters. Data analysis according to the biological behavior of the lesions revealed great heterogeneity. Statistically significant correlations were observed between the type of injury, age (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2005=\u2005.002) and gender (0.033). The environment of origin of the patients as well as the comorbidities reflected in most cases the nature of the process. Associations were also observed between the biological behavior of the lesions and the hemicranial topography (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2005=\u2005.019), the type of salivary gland (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2005=\u2005.024), and the surgical technique used (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2005&lt;\u2005.001). Most cases were identified in the major salivary glands, often in the parotid. The most common diseases are represented by nonspecific chronic sialadenitis (nonneoplastic lesion), pleomorphic adenoma and Warthin tumor (benign tumors), mucoepidermoid carcinoma (malignant tumor), and squamous carcinoma (secondary tumor). They presented axial diameters between 2 to 95\u2009mm. The most used curative technique was subtotal excision with facial nerve preservation. In conclusion, the study highlighted the main epidemiological aspects of salivary gland disorders. Some data agree with the specialty literature, and particular aspects are also observed. Therefore, this research is useful both in the medical and research fields.\n                  <\/jats:p>","DOI":"10.1097\/md.0000000000035751","type":"journal-article","created":{"date-parts":[[2023,10,20]],"date-time":"2023-10-20T11:25:45Z","timestamp":1697801145000},"page":"e35751","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["A retrospective study of nonneoplastic and neoplastic disorders of the salivary glands"],"prefix":"10.1097","volume":"102","author":[{"given":"Sorin","family":"Vamesu","sequence":"first","affiliation":[{"name":"Clinical Service of Anatomic Pathology, Departments of Pathology, \u201cSf. Apostol Andrei\u201d Emergency County Hospital, Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oana Andreea","family":"Ursica","sequence":"additional","affiliation":[{"name":"Clinical Service of Anatomic Pathology, Departments of Pathology, \u201cSf. Apostol Andrei\u201d Emergency County Hospital, Constanta, Romania"},{"name":"Faculty of Medicine, \u201cOvidius\u201d University of Constanta, Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Maria","family":"Gurita","sequence":"additional","affiliation":[{"name":"Clinical Service of Anatomic Pathology, Departments of Pathology, \u201cSf. Apostol Andrei\u201d Emergency County Hospital, Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raluca Ioana","family":"Voda","sequence":"additional","affiliation":[{"name":"Clinical Service of Anatomic Pathology, Departments of Pathology, \u201cSf. Apostol Andrei\u201d Emergency County Hospital, Constanta, Romania"},{"name":"Center for Research and Development of the Morphological and Genetic Studies of Malignant Pathology (CEDMOG), \u201cOvidius\u201d University of Constanta, Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Deacu","sequence":"additional","affiliation":[{"name":"Clinical Service of Anatomic Pathology, Departments of Pathology, \u201cSf. Apostol Andrei\u201d Emergency County Hospital, Constanta, Romania"},{"name":"Faculty of Medicine, \u201cOvidius\u201d University of Constanta, Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana","family":"Aschie","sequence":"additional","affiliation":[{"name":"Clinical Service of Anatomic Pathology, Departments of Pathology, \u201cSf. Apostol Andrei\u201d Emergency County Hospital, Constanta, Romania"},{"name":"Faculty of Medicine, \u201cOvidius\u201d University of Constanta, Constanta, Romania"},{"name":"Academy of Medical Sciences of Romania, Bucharest, Romania."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madalina","family":"Bosoteanu","sequence":"additional","affiliation":[{"name":"Clinical Service of Anatomic Pathology, Departments of Pathology, \u201cSf. Apostol Andrei\u201d Emergency County Hospital, Constanta, Romania"},{"name":"Faculty of Medicine, \u201cOvidius\u201d University of Constanta, Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgeta Camelia","family":"Cozaru","sequence":"additional","affiliation":[{"name":"Clinical Service of Anatomic Pathology, Departments of Pathology, \u201cSf. Apostol Andrei\u201d Emergency County Hospital, Constanta, Romania"},{"name":"Faculty of Medicine, \u201cOvidius\u201d University of Constanta, Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anca Florentina","family":"Mitroi","sequence":"additional","affiliation":[{"name":"Clinical Service of Anatomic Pathology, Departments of Pathology, \u201cSf. Apostol Andrei\u201d Emergency County Hospital, Constanta, Romania"},{"name":"Center for Research and Development of the Morphological and Genetic Studies of Malignant Pathology (CEDMOG), \u201cOvidius\u201d University of Constanta, Constanta, Romania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8039-3200","authenticated-orcid":false,"given":"Cristian Ionut","family":"Orasanu","sequence":"additional","affiliation":[{"name":"Clinical Service of Anatomic Pathology, Departments of Pathology, \u201cSf. 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