{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T19:35:57Z","timestamp":1770492957318,"version":"3.49.0"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"17","license":[{"start":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T00:00:00Z","timestamp":1714089600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,4,26]]},"abstract":"<jats:p>This study aimed to investigate the relationship between endoscopic gastroesophageal valve grading and mean nocturnal baseline impedance (MNBI) and postreflux swallow-induced peristaltic wave index (PSPWI) in patients with gastroesophageal reflux disease (GERD). A total of 120 patients diagnosed with GERD disease were included in the study. According to the classification of endoscopic gastroesophageal valves, the patients were divided into 5 groups, group 1 as baseline group, and Group 2-4 as Hill grade I-IV. Basic information about the patients was collected, including age and gender. The mean nocturnal baseline impedance and creep wave index induced by swallowing after rumination were measured by high resolution creep measurement technique. Through statistical analysis, the relationship between valve classification and observation index was discussed. In terms of MNBI, impedance values gradually decreased with increasing valve classification. The average impedance of the Grade 1 group was 23.5\u2009mm Hg\/cm<jats:sup>2<\/jats:sup>, while the average impedance of the Grade 5 group was 15.2\u2009mm Hg\/cm<jats:sup>2<\/jats:sup>. This reduction showed a significant decreasing trend (<jats:italic toggle=\"yes\">P<\/jats:italic>\u2005&lt;\u2005.001). In addition, in terms of the peristaltic wave index caused by swallowing after regurgitation, the peristaltic wave index gradually increased with the increase of valve classification. The mean index in the Grade 1 group was 1.8 beats\/min, while the mean index in the Grade 5 group was 3.6 beats\/min. This increase showed a significant positive relationship (<jats:italic toggle=\"yes\">P<\/jats:italic>\u2005&lt;\u2005.001). Endoscopic gastroesophageal valve grading was significantly correlated with MNBI and PSPWI in patients with GERD. These observations can serve as useful tools for assessing the severity of GERD and monitoring disease progression.<\/jats:p>","DOI":"10.1097\/md.0000000000037101","type":"journal-article","created":{"date-parts":[[2024,4,26]],"date-time":"2024-04-26T18:09:32Z","timestamp":1714154972000},"page":"e37101","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Relationship between endoscopic gastroesophageal valve grading and mean nocturnal baseline impedance and postreflux swallow-induced peristaltic wave index in patients with gastroesophageal reflux disease"],"prefix":"10.1097","volume":"103","author":[{"given":"Chunyan","family":"Xie","sequence":"first","affiliation":[{"name":"Department of Deputy Chief Physician of Gastroenterology, The First People\u2019s Hospital of Longquanyi District, Chengdu, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Peng","sequence":"additional","affiliation":[{"name":"Department of Chief Physician of Ultrasound, The First People\u2019s Hospital of Longquanyi District, Chengdu, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, The Second Traditional Chinese Medicine Hospital of Sichuan Province, Chengdu, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoli","family":"Xie","sequence":"additional","affiliation":[{"name":"Department of Deputy Chief Physician of Gastroenterology, The First People\u2019s Hospital of Longquanyi District, Chengdu, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhigang","family":"Xiu","sequence":"additional","affiliation":[{"name":"Department of Radiology, The First People\u2019s Hospital of Longquanyi District, Chengdu, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Deputy Chief Physician of Gastroenterology, The First People\u2019s Hospital of Longquanyi District, Chengdu, Sichuan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-5779-0123","authenticated-orcid":false,"given":"Anli","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, The First People\u2019s Hospital of Longquanyi District, Chengdu, Sichuan, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-20250503","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1016\/j.cgh.2022.01.025","article-title":"CGIT GERD Consensus Conference Participants. 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