{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T00:07:27Z","timestamp":1747181247343,"version":"3.40.5"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"13","license":[{"start":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T00:00:00Z","timestamp":1711670400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,3,29]]},"abstract":"<jats:sec>\n            <jats:title>Rationale:<\/jats:title>\n            <jats:p>Puerperal sepsis is a life-threatening condition caused by infection that can rapidly progress to multisystem infection and toxin-mediated shock. Symmetrical peripheral gangrene is defined as symmetrical distal ischemic damage in two or more sites in the absence of major vascular occlusive disease. The syndrome is devastating and rare. In this study, we introduce a case of puerperal septicemia complicated by symmetrical peripheral gangrene.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Patient concerns:<\/jats:title>\n            <jats:p>A 23-year-old woman delivered a live female infant vaginally after cervical balloon dilatation at 39 weeks of gestation. Persistent hyperthermia developed on the first postpartum day. After experiencing ventricular fibrillation, acute liver failure, and acute pulmonary edema, she developed blackened extremities on the 5th postpartum day.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Diagnoses:<\/jats:title>\n            <jats:p>Puerperal septicemia complicated by symmetrical peripheral gangrene.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Interventions:<\/jats:title>\n            <jats:p>Upon transfer to our hospital, the patient was enrolled in the intensive care unit and underwent anti-infective and amputation surgery.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Outcomes:<\/jats:title>\n            <jats:p>After the surgery, the patient recovered well and was successfully discharged from the hospital.<\/jats:p>\n          <\/jats:sec>\n          <jats:sec>\n            <jats:title>Lessons:<\/jats:title>\n            <jats:p>Early detection and timely treatment is the best way to reduce the mortality and sequelae of puerperal sepsis. Physicians should be alert to the possibility of comorbid symmetrical peripheral gangrene when sepsis patients present with hepatic impairment.<\/jats:p>\n          <\/jats:sec>","DOI":"10.1097\/md.0000000000037571","type":"journal-article","created":{"date-parts":[[2024,3,29]],"date-time":"2024-03-29T18:02:06Z","timestamp":1711735326000},"page":"e37571","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Puerperal septic shock complicated with symmetrical peripheral gangrene: A case report"],"prefix":"10.1097","volume":"103","author":[{"given":"Yue","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Obstetrics, The Second Affiliated Hospital of Kunming Medical University, Kunming, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cen","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, The Second Affiliated Hospital of Kunming Medical University, Kunming, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yajin","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, The Second Affiliated Hospital of Kunming Medical University, Kunming, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-6057-3504","authenticated-orcid":false,"given":"Wanqin","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics, The Second Affiliated Hospital of Kunming Medical University, Kunming, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-20250503","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1001\/jama.2019.9818","article-title":"Incidence of maternal sepsis and sepsis-related maternal deaths in the United States.","volume":"322","author":"Hensley","year":"2019","journal-title":"JAMA"},{"key":"R2-20250503","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/s13224-015-0750-5","article-title":"Study of obstetric admissions to the intensive care unit of a tertiary care hospital.","volume":"66","author":"Rathod","year":"2016","journal-title":"J Obstet Gynaecol India"},{"key":"R3-20250503","doi-asserted-by":"crossref","first-page":"663","DOI":"10.1111\/1471-0528.12892","article-title":"Maternal sepsis incidence, aetiology and outcome for mother and fetus: a prospective study.","volume":"122","author":"Knowles","year":"2015","journal-title":"BJOG"},{"key":"R4-20250503","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1177\/000313480006600217","article-title":"Symmetrical peripheral gangrene: a new presentation of an old disease.","volume":"66","author":"Knight","year":"2000","journal-title":"Am Surg"},{"key":"R5-20250503","doi-asserted-by":"crossref","first-page":"870","DOI":"10.4103\/ijccm.IJCCM_379_18","article-title":"Management of symmetrical peripheral gangrene.","volume":"22","author":"Foead","year":"2018","journal-title":"Indian J Crit Care Med"},{"key":"R6-20250503","doi-asserted-by":"crossref","first-page":"100149","DOI":"10.1016\/j.ajogmf.2020.100149","article-title":"Maternal sepsis.","volume":"2","author":"Escobar","year":"2020","journal-title":"Am J Obstet Gynecol MFM"},{"key":"R7-20250503","doi-asserted-by":"crossref","first-page":"100033","DOI":"10.1016\/j.eurox.2019.100033","article-title":"Double-balloon catheter for induction of labor in 362 women with and without prior cesarean section.","volume":"4","author":"Boisen","year":"2019","journal-title":"Eur J Obstet Gynecol Reprod Biol X"},{"key":"R8-20250503","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1097\/AOG.0000000000001028","article-title":"Maternal deaths due to sepsis in the state of Michigan, 1999-2006.","volume":"126","author":"Bauer","year":"2015","journal-title":"Obstet Gynecol"},{"key":"R9-20250503","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1007\/s00330-016-4471-7","article-title":"Magnetic resonance imaging of pelvic floor dysfunction-joint recommendations of the ESUR and ESGAR Pelvic Floor Working Group.","volume":"27","author":"El Sayed","year":"2017","journal-title":"Eur Radiol"},{"key":"R10-20250503","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1001\/jama.2016.0289","article-title":"Developing a new definition and assessing new clinical criteria for septic shock: for the third international consensus definitions for Sepsis and septic shock (Sepsis-3).","volume":"315","author":"Shankar-Hari","year":"2016","journal-title":"JAMA"},{"key":"R11-20250503","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12978-017-0321-6","article-title":"Towards a consensus definition of maternal sepsis: results of a systematic review and expert consultation.","volume":"14","author":"Bonet","year":"2017","journal-title":"Reprod Health"},{"key":"R12-20250503","doi-asserted-by":"crossref","first-page":"103094","DOI":"10.1016\/j.transci.2021.103094","article-title":"Symmetrical peripheral gangrene in critical illness.","volume":"60","author":"Warkentin","year":"2021","journal-title":"Transfus Apher Sci"},{"key":"R13-20250503","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1111\/jth.13219","article-title":"Shock, acute disseminated intravascular coagulation, and microvascular thrombosis: is \u201cshock liver\u201d the unrecognized provocateur of ischemic limb necrosis?","volume":"14","author":"Warkentin","year":"2016","journal-title":"J Thromb Haemost"},{"key":"R14-20250503","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1056\/NEJMra1316259","article-title":"Ischemic limb gangrene with pulses.","volume":"373","author":"Warkentin","year":"2015","journal-title":"N Engl J Med"},{"key":"R15-20250503","article-title":"A hospital considering a 1-hour bundle for management of sepsis.","volume":"380","author":"Angela","year":"2019","journal-title":"N Engl J Med"}],"container-title":["Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/MD.0000000000037571","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T23:01:30Z","timestamp":1746313290000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/MD.0000000000037571"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,29]]},"references-count":15,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1097\/md.0000000000037571","relation":{},"ISSN":["0025-7974","1536-5964"],"issn-type":[{"type":"print","value":"0025-7974"},{"type":"electronic","value":"1536-5964"}],"subject":[],"published":{"date-parts":[[2024,3,29]]}}}