{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T02:28:37Z","timestamp":1793759317283,"version":"4.6.1"},"reference-count":27,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"21","license":[{"start":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T00:00:00Z","timestamp":1716508800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,5,24]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Here we investigated the effect of a stellate ganglion block on the perioperative mechanical ventilation and postoperative recovery of respiratory function of elderly patients with infectious shock.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Thirty-six elderly patients with septic shock who underwent emergency general anesthesia at our hospital were randomly divided into treatment (T) and control (C) groups (n\u2005=\u200518 each). Group T received a preoperative stellate ganglion block, whereas group C received normal saline. Procalcitonin and C-reactive protein levels were compared preoperatively and at 1 and 7 days postoperative. Mean arterial pressure, oxygen saturation, and mean pulmonary artery pressure were measured preoperative and postoperative as well as at 1 and 7 days later. A blood gas analysis was performed preoperatively, at the end of the operation, during extubation, and at 1 and 7 days postoperative. Intubation under general anesthesia, the completion of anesthesia, and spontaneous respiratory recovery involve pulmonary dynamic compliance, plateau pressure, and mechanical ventilation.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      General condition did not differ significantly between groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2005&gt;\u2005.05). However, mean arterial pressure at the end of surgery and at 1 and 7 days postoperative were significantly higher in group T versus C (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2005&lt;\u2005.05). Furthermore, mean oxygen saturation at the end of surgery and at 1 and 7 days postoperative was significantly lower in group T versus C (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2005&lt;\u2005.05), while procalcitonin and C-reactive protein levels were significantly lower at 1 and 7 days postoperative. Group T had significantly better arterial partial pressure of carbon dioxide, partial pressure of oxygen, and partial pressure of oxygen\/fraction of inspired oxygen than group C at the end of surgery, during extubation, and at 1 and 7 days postoperative (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2005&lt;\u2005.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Group T exhibited superior inflammatory responses and respiratory function. Stellate ganglion block in elderly patients with septic shock reduces inflammation, improves mechanical ventilation perioperatively, and promotes postoperative recovery and respiratory function.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/md.0000000000038166","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T14:04:40Z","timestamp":1716559480000},"page":"e38166","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Clinical effect of perioperative stellate ganglion block on mechanical ventilation and respiratory function of elderly patients with septic shock"],"prefix":"10.1097","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-1839-537X","authenticated-orcid":false,"given":"Yingchuan","family":"Yuan","sequence":"first","affiliation":[{"name":"Department of Anesthesiology, The Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Second Affiliated Hospital of Xinjiang Medical University, Urumqi, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-20250504","first-page":"e35174","article-title":"A review of stellate ganglion block as an adjunctive treatment modality.","volume":"15","author":"Kirkpatrick","year":"2023","journal-title":"Cureus"},{"key":"R3-20250504","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.jiph.2019.11.021","article-title":"Effect of lung protective ventilation on perioperative pulmonary infection in elderly patients with mild to moderate COPD under general anesthesia.","volume":"13","author":"Ji","year":"2020","journal-title":"J Infect Public 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A conceptual view with a focus on Covid-19.","volume":"237","author":"Fischer","year":"2022","journal-title":"Auton Neurosci"},{"key":"R17-20250504","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1111\/neup.12655","article-title":"Stellate ganglion ischemia on the prevention of pulmonary vasospasm during bilateral carotid artery ligation: the first experimental study.","volume":"40","author":"Arslan","year":"2020","journal-title":"Neuropathology"},{"key":"R18-20250504","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1186\/s40001-022-00860-3","article-title":"Stellate ganglion block relieves acute lung injury induced by severe acute pancreatitis via the miR-155-5p\/SOCS5\/JAK2\/STAT3 axis.","volume":"27","author":"Wang","year":"2022","journal-title":"Eur J Med Res"},{"key":"R19-20250504","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/ACO.0000000000000955","article-title":"Mechanical ventilation in septic shock.","volume":"34","author":"Maccagnan Pinheiro Besen","year":"2021","journal-title":"Curr Opin Anaesthesiol"},{"key":"R20-20250504","doi-asserted-by":"crossref","first-page":"110000","DOI":"10.1016\/j.mehy.2020.110000","article-title":"How does stellate ganglion block alleviate immunologically-linked disorders?","volume":"144","author":"Lipov","year":"2020","journal-title":"Med Hypotheses"},{"key":"R21-20250504","first-page":"3864","article-title":"Effects of stellate ganglionic block on hemodynamic changes and intrapulmonary shunt in perioperative patients with esophageal cancer.","volume":"18","author":"Guo","year":"2014","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"R22-20250504","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1186\/s12871-022-01814-2","article-title":"Cervical sympathetic trunk transection alleviates acute lung injury caused by intestinal obstruction via inhibition of phospholipase A2 in rats.","volume":"22","author":"Gu","year":"2022","journal-title":"BMC Anesthesiol"},{"key":"R23-20250504","doi-asserted-by":"crossref","first-page":"1","DOI":"10.2152\/jmi.61.1","article-title":"Role of surfactant protein A in non-infectious lung diseases.","volume":"61","author":"Goto","year":"2014","journal-title":"J Med Invest"},{"key":"R24-20250504","doi-asserted-by":"crossref","first-page":"910","DOI":"10.1161\/CIRCULATIONAHA.117.027451","article-title":"Contribution of impaired parasympathetic activity to right ventricular dysfunction and pulmonary vascular remodeling in pulmonary arterial hypertension.","volume":"137","author":"da Silva Gon\u00e7alves B\u00f3s","year":"2018","journal-title":"Circulation"},{"key":"R25-20250504","doi-asserted-by":"crossref","first-page":"5577","DOI":"10.12998\/wjcc.v10.i17.5577","article-title":"Clinical evaluation of prone position ventilation in the treatment of acute respiratory distress syndrome induced by sepsis.","volume":"10","author":"Xia","year":"2022","journal-title":"World J Clin Cases"},{"key":"R26-20250504","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.anclin.2015.05.003","article-title":"Physiology considerations in geriatric patients.","volume":"33","author":"Alvis","year":"2015","journal-title":"Anesthesiol Clin"},{"key":"R27-20250504","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s13613-019-0498-7","article-title":"Current use of vasopressors in septic shock.","volume":"9","author":"Scheeren","year":"2019","journal-title":"Ann Intensive Care"},{"key":"R28-20250504","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1007\/s11906-020-01111-8","article-title":"Stellate Ganglion blockade: an intervention for the management of ventricular arrhythmias.","volume":"22","author":"Ganesh","year":"2020","journal-title":"Curr Hypertens Rep"}],"container-title":["Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/MD.0000000000038166","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,3]],"date-time":"2025-05-03T20:55:38Z","timestamp":1746305738000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/10.1097\/MD.0000000000038166"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,24]]},"references-count":27,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.1097\/md.0000000000038166","relation":{},"ISSN":["0025-7974","1536-5964"],"issn-type":[{"value":"0025-7974","type":"print"},{"value":"1536-5964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,24]]}}}