{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T14:45:54Z","timestamp":1754145954027,"version":"3.41.2"},"reference-count":30,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T00:00:00Z","timestamp":1736467200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1,10]]},"abstract":"<jats:p>This study analyzes the risk factors related to the complications of anterior thoracolumbar tuberculosis in adults and to provide clinical reference. A total of 98 adult patients with thoracolumbar tuberculosis undergoing anterior surgery in our hospital from February 2020 to December 2023 were selected, and the clinical data and postoperative complications were collected. The clinical characteristics were analyzed, and the risk factors related to surgical complications were analyzed by univariate analysis and multi-factor logistic regression model. A total of 54 patients had 75 postoperative complications of different degrees. Univariate analysis showed that patient age, preoperative hemoglobin (Hb) level, bone graft fusion method, intraoperative blood loss, and postoperative neurological function [Asian neurological function classification] were correlated with the occurrence of postoperative complications (<jats:italic toggle=\"yes\">P<\/jats:italic>\u2005&lt;\u2005.05). Multivariate Logistic regression analysis showed that age over 60 years old, preoperative Hb\u2005&lt;\u2005100\u2009g\/L, blood loss\u2005\u2265\u2005800\u2009mL, bone graft fusion method were independent risk factors for anterior postoperative complications of thoracolumbar tuberculosis (<jats:italic toggle=\"yes\">P<\/jats:italic>\u2005&lt;\u2005.05). The independent risk factors for surgical complications of anterior thoracolumbar tuberculosis were age over 60 years old, preoperative Hb\u2005&lt;\u2005100\u2009g\/L, blood loss\u2005\u2265\u2005800\u2009mL, titanium cage by bone graft fusion. Controlling these variable factors before operation can reduce the incidence of postoperative complications.<\/jats:p>","DOI":"10.1097\/md.0000000000041252","type":"journal-article","created":{"date-parts":[[2025,1,10]],"date-time":"2025-01-10T15:07:35Z","timestamp":1736521655000},"page":"e41252","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Analysis of influencing factors for complications of anterior thoracolumbar tuberculosis surgery in adults"],"prefix":"10.1097","volume":"104","author":[{"given":"Wei","family":"Lin","sequence":"first","affiliation":[{"name":"Department of Spinal Surgery, Shenzhen Third People\u2019s Hospital, Shenzhen, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinzhu","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Spinal Surgery, Shenzhen Third People\u2019s Hospital, Shenzhen, China."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zirui","family":"Zhan","sequence":"additional","affiliation":[{"name":"Department of Spinal Surgery, Shenzhen Third People\u2019s Hospital, Shenzhen, China."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-20250717","doi-asserted-by":"crossref","first-page":"e468","DOI":"10.1016\/j.wneu.2019.12.036","article-title":"Treatment of monosegment spinal tuberculosis via posterior unilateral vertebral lamina fenestration debridement and bone grafting fusion combined with laminar reconstruction and internal fixation: A retrospective case-control study with a minimum 5-year follow-up.","volume":"135","author":"Liu","year":"2020","journal-title":"World Neurosurg"},{"key":"R2-20250717","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1111\/ans.17430","article-title":"The surgical management of spinal disorders in lysosomal storage diseases: a systematic 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