{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T17:38:45Z","timestamp":1757612325265,"version":"3.44.0"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"17","license":[{"start":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T00:00:00Z","timestamp":1745539200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,4,25]]},"abstract":"<jats:p>The utility of lung ultrasound (LUS) in evaluation of coronavirus disease (COVID-19) with pneumonia has not yet been elucidated. The main objective of study is to determine whether LUS can effectively predict the prognosis in intensive care unit (ICU), including mortality and disease severity. It\u2019s also aimed to determine whether LUS will provide a threshold value to predict mortality in COVID-19 cases. In this prospective observational study, 90 patients admitted to the ICU with COVID-19 pneumonia and respiratory failure were included. A LUS cutoff score of 21 on admission demonstrated sensitivity of 97% and specificity of 68% for predicting mortality. Baseline LUS scores were found to be significantly higher in nonsurvivor group(<jats:italic toggle=\"yes\">P<\/jats:italic>\u2005&lt;\u2005.001) whereas APACHE II, sequential organ failure assessment (SOFA), charlson comorbidity index (CCI), nutrition risk in critically ill (NUTRIC) scores, serum lactate, procalcitonin, ferritin, D-dimer levels and heart rate were also significantly found to be higher in nonsurvivor group(<jats:italic toggle=\"yes\">P<\/jats:italic>\u2005&lt;\u2005.05). Overall mean progression-free-survival (PFS) rate was significantly longer in patients with LUS scores\u2005&lt;\u200521, (mean-survival 23.8 days) compared to those with LUS scores\u2005\u2265\u200521 (mean-survival 12.5 days) (<jats:italic toggle=\"yes\">P<\/jats:italic>\u2005&lt;\u2005.05). Multivariate Cox-regression analysis identified a LUS score\u2005\u2265\u200521 was an independent risk factor for mortality during ICU stay (<jats:italic toggle=\"yes\">P<\/jats:italic>\u2005=\u2005.002). LUS performed at ICU admission can serve as a prognostic indicator for patients with COVID-19 pneumonia. By identifying high-risk groups and monitoring these patients closely using LUS, healthcare providers may enhance resource utilization and potentially improve patient outcomes.<\/jats:p>","DOI":"10.1097\/md.0000000000042010","type":"journal-article","created":{"date-parts":[[2025,4,28]],"date-time":"2025-04-28T23:00:55Z","timestamp":1745881255000},"page":"e42010","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["The role of early lung ultrasound score measurement in determining prognosis in COVID-19 ICU patients with respiratory failure"],"prefix":"10.1097","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7462-3134","authenticated-orcid":false,"given":"Sinem","family":"Bayrak\u00e7i","sequence":"first","affiliation":[{"name":"Department of ICU, Gaziantep City Hospital, Gaziantep, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4121-1931","authenticated-orcid":false,"given":"Nazire","family":"Ate\u015f Ayhan","sequence":"additional","affiliation":[{"name":"Department of ICU, Sanliurfa Training and Researh Hospital, Sanliurfa, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9182-7270","authenticated-orcid":false,"given":"Ahmet","family":"Firat","sequence":"additional","affiliation":[{"name":"Department of ICU, Aksaray Training and Researh Hospital, Aksaray, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2935-522X","authenticated-orcid":false,"given":"Yurdaer","family":"Bulut","sequence":"additional","affiliation":[{"name":"Department of ICU, Adana Baskent University Seyhan Application and Research Hospital, Adana, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fcl\u015fah","family":"Seydao\u011flu","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Cukurova University Faculty of Medicine, Adana, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emre","family":"Karako\u00e7","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine and ICU, Cukurova University Faculty of Medicine, Adana, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7320-976X","authenticated-orcid":false,"given":"Oya","family":"Baydar Toprak","sequence":"additional","affiliation":[{"name":"Department of Chest Diseases, Cukurova University Faculty of Medicine, Adana, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4535-705X","authenticated-orcid":false,"given":"Ezgi","family":"\u00d6zyilmaz","sequence":"additional","affiliation":[{"name":"Department of Chest Diseases and ICU, Cukurova University Faculty of Medicine, Adana, Turkey."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-20250904","doi-asserted-by":"crossref","first-page":"506","DOI":"10.1016\/S2213-2600(20)30161-2","article-title":"Intensive care management of coronavirus disease 2019 (COVID-19): challenges and recommendations.","volume":"8","author":"Phua","year":"2020","journal-title":"Lancet Respir Med"},{"key":"R2-20250904","doi-asserted-by":"crossref","first-page":"87","DOI":"10.2214\/AJR.20.23034","article-title":"Coronavirus disease 2019(COVID-19): a systematic review of imaging findings in 919 patients.","volume":"215","author":"Salehi","year":"2020","journal-title":"AJR Am J 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