{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T18:43:39Z","timestamp":1785609819461,"version":"3.56.0"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"36","license":[{"start":{"date-parts":[[2025,9,5]],"date-time":"2025-09-05T00:00:00Z","timestamp":1757030400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>As a minimally invasive technique, Fu\u2019s subcutaneous needling (FSN) has been widely adopted in Chinese clinical practice for managing neck-type cervical spondylosis (CS). However, current evidence regarding its therapeutic efficacy remains inconclusive due to methodological limitations in existing studies. This systematic review and meta-analysis therefore sought to quantitatively synthesize available randomized controlled trials to evaluate the clinical effectiveness and safety of FSN for this prevalent musculoskeletal disorder.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This study protocol was prospectively registered in PROSPERO (Registration ID: CRD420251036627). The databases searched include PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang Data Knowledge Service Platform (Wanfang), VIP Database (VIP), and China Biology Medicine disc (CBM). A comprehensive search was conducted across the 8 electronic databases from their inception through April 18, 2025. Eligible studies included randomized controlled trials comparing FSN with non-FSN therapies for neck-type CS.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      This study included 10 clinical studies with a total of 696 patients suffering from neck-type CS. The results of the meta - analysis revealed that the experimental group had significant advantages over the control group in terms of clinical efficacy. Specifically, for the total effective rate (odds ratio\u2005=\u20055.45, 95% confidence intervals [CI]\u2005=\u2005[2.75, 10.81],\n                      <jats:italic toggle=\"yes\">Z<\/jats:italic>\n                      \u2005=\u20054.85,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2005\n                      <jats:italic toggle=\"yes\">&lt;<\/jats:italic>\n                      \u2005.00001), cure rate (odds ratio\u2005=\u20052.25, 95% CI\u2005=\u2005[1.51, 3.34],\n                      <jats:italic toggle=\"yes\">Z<\/jats:italic>\n                      \u2005=\u20054.01,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2005&lt;\u2005.00001), visual analogue scale score (VAS, mean difference\u2005=\u2005\u22121.21, 95% CI\u2005=\u2005[\u22121.30, \u22121.12],\n                      <jats:italic toggle=\"yes\">Z<\/jats:italic>\n                      \u2005=\u200525.10,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2005&lt;\u2005.00001), and Neck Disability Index score (NDI, mean difference\u2005=\u2005\u22121.33, 95% CI\u2005=\u2005[\u22121.92, \u22120.75],\n                      <jats:italic toggle=\"yes\">Z<\/jats:italic>\n                      \u2005=\u20054.48,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2005&lt;\u2005.00001), the experimental group outperformed the control group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>This study indicates that FSN is a safe and effective strategy for managing neck-type CS. Therefore, it can be considered as a common clinical treatment modality for neck-type CS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/md.0000000000044299","type":"journal-article","created":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T18:09:35Z","timestamp":1757354975000},"page":"e44299","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Efficacy of Fu\u2019s subcutaneous needling in the treatment of neck-type cervical spondylosis: A systematic review and meta-analysis"],"prefix":"10.1097","volume":"104","author":[{"given":"Hui","family":"Ren","sequence":"first","affiliation":[{"name":"Jiangxi University of Chinese Medicine, Nanchang, China"},{"name":"The Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaole","family":"Wang","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Fang","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lang","family":"Liu","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaolan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Jiangxi University of Chinese Medicine, Nanchang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingxian","family":"Lv","sequence":"additional","affiliation":[{"name":"Jiangxi University of Chinese Medicine, Nanchang, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fushui","family":"Liu","sequence":"additional","affiliation":[{"name":"The Affiliated Hospital of Jiangxi University of Chinese Medicine, Nanchang, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20251029","first-page":"47","article-title":"The incidence of cervical spondylosis decreases with aging in the elderly, and increases with aging in the young and adult population: a hospital - 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