{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T03:31:48Z","timestamp":1769830308653,"version":"3.49.0"},"reference-count":35,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"46","license":[{"start":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T00:00:00Z","timestamp":1763078400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,11,14]]},"abstract":"<jats:p>\n                    This study was performed to investigate the factors associated with the development of postoperative aspiration pneumonia (PAP) after abdominal surgery for digestive cancers. The study involved 420 patients who had undergone abdominal surgery for digestive cancers. The patients were divided into a PAP group (n\u2005=\u200513) and non-PAP group (n\u2005=\u2005407), and clinicopathological factors were compared between the 2 groups. Logistic regression analysis was used to assess the predictors of PAP, and develop a formula for the prediction of PAP. The PAP group showed a higher white blood cell count, C-reactive protein concentration, and modified Glasgow prognostic score and a lower albumin concentration than the non-PAP group (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2005&lt;\u2005.05). The PAP group also showed a significantly higher rate of frailty and longer postoperative hospital stay (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2005&lt;\u2005.05). The multivariate analysis revealed that cerebrovascular disease, respiratory complications, and frailty were independent predictive factors of PAP (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2005&lt;\u2005.05). A prediction formula established using these factors showed a sensitivity of 92.3% and specificity of 76.4%. Evaluation of the preoperative frailty status is important for risk stratification and prevention of postoperative morbidity in patients undergoing surgery.\n                  <\/jats:p>","DOI":"10.1097\/md.0000000000045697","type":"journal-article","created":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T21:00:15Z","timestamp":1763154015000},"page":"e45697","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Frailty as a predictor of postoperative aspiration pneumonia after abdominal surgery for digestive cancers"],"prefix":"10.1097","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3847-751X","authenticated-orcid":false,"given":"Shinichiro","family":"Yamada","sequence":"first","affiliation":[{"name":"Department of Surgery, Tokushima University, Tokushima City, Tokushima, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Morine","sequence":"additional","affiliation":[{"name":"Department of Surgery, Tokushima University, Tokushima City, Tokushima, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsuya","family":"Ikemoto","sequence":"additional","affiliation":[{"name":"Department of Surgery, Tokushima University, Tokushima City, Tokushima, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu","family":"Saito","sequence":"additional","affiliation":[{"name":"Department of Surgery, Tokushima University, Tokushima City, Tokushima, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Teraoku","sequence":"additional","affiliation":[{"name":"Department of Surgery, Tokushima University, Tokushima City, Tokushima, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuo","family":"Shimada","sequence":"additional","affiliation":[{"name":"Department of Surgery, Tokushima University, Tokushima City, Tokushima, Japan."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-20251121","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1245\/s10434-020-08742-w","article-title":"Significance of frailty in prognosis after hepatectomy for elderly patients with hepatocellular carcinoma.","volume":"28","author":"Yamada","year":"2021","journal-title":"Ann Surg Oncol"},{"key":"R2-20251121","doi-asserted-by":"crossref","first-page":"581","DOI":"10.7326\/0003-4819-144-8-200604180-00009","article-title":"Preoperative pulmonary risk stratification for noncardiothoracic surgery: systematic review for the American College of Physicians.","volume":"144","author":"Smetana","year":"2006","journal-title":"Ann Intern Med"},{"key":"R3-20251121","doi-asserted-by":"crossref","first-page":"1338","DOI":"10.1097\/ALN.0b013e3181fc6e0a","article-title":"Prediction of postoperative pulmonary complications in a population-based surgical cohort.","volume":"113","author":"Canet","year":"2010","journal-title":"Anesthesiology"},{"key":"R4-20251121","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.jamcollsurg.2004.05.276","article-title":"Hospital costs associated with surgical complications: a report from the private-sector national surgical quality improvement program.","volume":"199","author":"Dimick","year":"2004","journal-title":"J Am Coll Surg"},{"key":"R5-20251121","doi-asserted-by":"crossref","first-page":"2163","DOI":"10.1097\/CCM.0b013e31821f0522","article-title":"Clinical and economic burden of postoperative pulmonary complications: patient safety summit on definition, risk-reducing interventions, and preventive strategies.","volume":"39","author":"Shander","year":"2011","journal-title":"Crit Care Med"},{"key":"R6-20251121","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1111\/j.1445-2197.2006.03993.x","article-title":"Risk factors for postoperative pulmonary complications in upper abdominal surgery.","volume":"77","author":"Kanat","year":"2007","journal-title":"ANZ J. 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