{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T13:20:05Z","timestamp":1787750405562,"version":"build-2784847793"},"reference-count":38,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"25","license":[{"start":{"date-parts":[[2026,6,19]],"date-time":"2026-06-19T00:00:00Z","timestamp":1781827200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,6,19]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>\n                      Obstructive sleep apnea (OSA) increases the risk of multiple chronic diseases such as diabetes and cardiovascular disease, posing a substantial threat to public health. Therefore, this study aimed to investigate the association between physical exercise and OSA symptoms. A representative sample of 7180 individuals aged 20 years and older was selected from the 2015 to 2018 United States National Health and Nutrition Examination Survey. Binary logistic regression was used to analyze the association between physical activity and OSA symptoms. Threshold effect analysis and restricted cubic spline curves were applied to evaluate the dose-response relationships of exercise duration and metabolic equivalents of tasks (METs) with OSA symptoms. After adjustment for all covariates in the multivariable analysis, exercise was significantly inversely associated with OSA symptoms (odds ratio [OR]\u2005=\u20050.84, 95% confidence interval [CI]: 0.76\u20130.93,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2005&lt;\u2005.05). Compared with non-exercisers, moderate-intensity exercisers had OR\u2005=\u20050.89 (95% CI: 0.79\u20131.00,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2005=\u2005.059), while high-intensity exercisers showed a stronger association (OR\u2005=\u20050.79, 95% CI: 0.69\u20130.90,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2005&lt;\u2005.05). Threshold analyses suggested potential statistical inflection points at approximately 75 minutes of exercise and 320 METs (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      \u2005&lt;\u2005.05). Physical activity was inversely associated with OSA symptoms, with high-intensity exercise associated with a relatively lower likelihood of OSA symptoms. The association between exercise and OSA symptoms showed a potential change near 75 minutes of exercise and 320 METs. Future population-based intervention studies should assess the clinical application of these activity levels in improving OSA outcomes.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1097\/md.0000000000049326","type":"journal-article","created":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T06:00:32Z","timestamp":1782108032000},"page":"e49326","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Association of physical exercise characteristics with obstructive sleep apnea symptoms: A cross-sectional study"],"prefix":"10.1097","volume":"105","author":[{"given":"Yan","family":"Sun","sequence":"first","affiliation":[{"name":"School of Police Combat Training, People\u2019s Public Security University of China, Beijing, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-9452-3886","authenticated-orcid":false,"given":"Kexin","family":"Zhu","sequence":"additional","affiliation":[{"name":"School of Physical Education (Main Campus), Zhengzhou University, Zhengzhou, Henan, People\u2019s Republic of China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-20260820","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1016\/S0140-6736(13)60734-5","article-title":"Adult obstructive sleep apnoea.","volume":"383","author":"Jordan","year":"2014","journal-title":"Lancet"},{"key":"R2-20260820","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.cxom.2007.05.001","article-title":"Oral appliances in the treatment of obstructive sleep apnea.","volume":"15","author":"Smith","year":"2007","journal-title":"Atlas Oral Maxillofac Surg Clin North Am"},{"key":"R3-20260820","first-page":"541","article-title":"Acute life-threatening hypoxemia during mechanical ventilation.","volume":"23","author":"Piraino","year":"2017","journal-title":"Curr Opin Crit Care"},{"key":"R4-20260820","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1016\/j.ccm.2022.11.007","article-title":"Pathophysiology of hypoxemia in COVID-19 lung disease.","volume":"44","author":"Swenson","year":"2023","journal-title":"Clin Chest Med"},{"key":"R5-20260820","doi-asserted-by":"crossref","first-page":"101583","DOI":"10.1016\/j.smrv.2021.101583","article-title":"Sleep and anxiety: from mechanisms to interventions.","volume":"61","author":"Chellappa","year":"2022","journal-title":"Sleep Med Rev"},{"key":"R6-20260820","doi-asserted-by":"crossref","first-page":"5241","DOI":"10.1523\/JNEUROSCI.2330-22.2023","article-title":"Is short sleep bad for the brain? 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