{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T15:50:02Z","timestamp":1793893802448,"version":"4.8.0"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2011,1]]},"DOI":"10.1097\/md.0b013e318205a4c6","type":"journal-article","created":{"date-parts":[[2010,12,31]],"date-time":"2010-12-31T12:20:29Z","timestamp":1293798029000},"page":"19-27","source":"Crossref","is-referenced-by-count":880,"title":["The Five-Factor Score Revisited"],"prefix":"10.1097","volume":"90","author":[{"given":"Lo\u00efc","family":"Guillevin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Pagnoux","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphaele","family":"Seror","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred","family":"Mahr","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luc","family":"Mouthon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philippe Le","family":"Toumelin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-2-20210309","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1002\/art.20082","article-title":"Predicting mortality in systemic Wegener's granulomatosis: a survival analysis based on 93 patients.","volume":"51","author":"Bligny","year":"2004","journal-title":"Arthritis Rheum"},{"key":"R2-2-20210309","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1136\/ard.2008.088302","article-title":"Risk factors for major infections in Wegener granulomatosis: analysis of 113 patients.","volume":"68","author":"Charlier","year":"2009","journal-title":"Ann Rheum Dis"},{"key":"R3-2-20210309","doi-asserted-by":"crossref","first-page":"686","DOI":"10.1002\/art.22679","article-title":"Churg-Strauss syndrome with poor-prognosis factors: a prospective multicenter trial comparing glucocorticoids and six or twelve cyclophosphamide pulses in forty-eight patients.","volume":"57","author":"Cohen","year":"2007","journal-title":"Arthritis Rheum"},{"key":"R4-2-20210309","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1111\/j.2517-6161.1972.tb00899.x","article-title":"Regression models and life tables.","volume":"34","author":"Cox","year":"1972","journal-title":"J R Stat Soc"},{"key":"R5-2-20210309","first-page":"31","article-title":"Development and validation of a disease extent index for Wegener's granulomatosis.","volume":"55","author":"de Groot","year":"2001","journal-title":"Clin Nephrol"},{"key":"R6-2-20210309","doi-asserted-by":"crossref","first-page":"670","DOI":"10.7326\/0003-4819-150-10-200905190-00004","article-title":"Pulse versus daily oral cyclophosphamide for induction of remission in antineutrophil cytoplasmic antibody-associated vasculitis: a randomized trial.","volume":"150","author":"de Groot","year":"2009","journal-title":"Ann Intern Med"},{"key":"R7-2-20210309","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1097\/00002281-199601000-00002","article-title":"Clinical disease activity in systemic vasculitis.","volume":"8","author":"Exley","year":"1996","journal-title":"Curr Opin Rheumatol"},{"key":"R8-2-20210309","doi-asserted-by":"crossref","first-page":"666","DOI":"10.1002\/1529-0131(200103)44:3<666::AID-ANR116>3.0.CO;2-A","article-title":"Long-term followup of polyarteritis nodosa, microscopic polyangiitis, and Churg-Strauss syndrome: analysis of four prospective trials including 278 patients.","volume":"44","author":"Gayraud","year":"2001","journal-title":"Arthritis Rheum"},{"key":"R9-2-20210309","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1002\/art.10922","article-title":"Treatment of polyarteritis nodosa and microscopic polyangiitis with poor prognosis factors: a prospective trial comparing glucocorticoids and six or twelve cyclophosphamide pulses in sixty-five patients.","volume":"49","author":"Guillevin","year":"2003","journal-title":"Arthritis Rheum"},{"key":"R10-2-20210309","doi-asserted-by":"crossref","first-page":"2187","DOI":"10.1002\/art.1780401213","article-title":"A prospective, multicenter, randomized trial comparing steroids and pulse cyclophosphamide versus steroids and oral cyclophosphamide in the treatment of generalized Wegener's granulomatosis.","volume":"40","author":"Guillevin","year":"1997","journal-title":"Arthritis Rheum"},{"key":"R11-2-20210309","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1097\/00005792-199601000-00003","article-title":"Prognostic factors in polyarteritis nodosa and Churg-Strauss syndrome. A prospective study in 342 patients.","volume":"75","author":"Guillevin","year":"1996","journal-title":"Medicine (Baltimore)"},{"key":"R12-2-20210309","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1097\/01.md.0000180792.80212.5e","article-title":"Hepatitis B virus-associated polyarteritis nodosa: clinical characteristics, outcome, and impact of treatment in 115 patients.","volume":"84","author":"Guillevin","year":"2005","journal-title":"Medicine (Baltimore)"},{"key":"R13-2-20210309","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1136\/bmj.290.6484.1775","article-title":"Pulmonary haemorrhage complicating Wegener's granulomatosis and microscopic polyarteritis.","volume":"290","author":"Haworth","year":"1985","journal-title":"Br Med J (Clin Res Ed)"},{"key":"R14-2-20210309","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1681\/ASN.V7123","article-title":"Prognostic markers in patients with antineutrophil cytoplasmic autoantibody-associated microscopic polyangiitis and glomerulonephritis.","volume":"7","author":"Hogan","year":"1996","journal-title":"J Am Soc Nephrol"},{"key":"R15-2-20210309","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1056\/NEJMoa020286","article-title":"A randomized trial of maintenance therapy for vasculitis associated with antineutrophil cytoplasmic autoantibodies.","volume":"349","author":"Jayne","year":"2003","journal-title":"N Engl J Med"},{"key":"R16-2-20210309","doi-asserted-by":"crossref","first-page":"2180","DOI":"10.1681\/ASN.2007010090","article-title":"Randomized trial of plasma exchange or high-dosage methylprednisolone as adjunctive therapy for severe renal vasculitis.","volume":"18","author":"Jayne","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"R17-2-20210309","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1002\/art.1780370206","article-title":"Nomenclature of systemic vasculitides. Proposal of an international consensus conference.","volume":"37","author":"Jennette","year":"1994","journal-title":"Arthritis Rheum"},{"key":"R18-2-20210309","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1164\/ajrccm.155.3.9116994","article-title":"Diffuse alveolar hemorrhage with underlying isolated, pauciimmune pulmonary capillaritis.","volume":"155","author":"Jennings","year":"1997","journal-title":"Am J Respir Crit Care Med"},{"key":"R19-2-20210309","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1080\/01621459.1958.10501452","article-title":"Nonparametric estimation from incomplete observations.","volume":"53","author":"Kaplan","year":"1958","journal-title":"J Am Stat Assoc"},{"key":"R20-2-20210309","doi-asserted-by":"crossref","first-page":"972","DOI":"10.1378\/chest.06-2464","article-title":"Outcome of patients with small-vessel vasculitis admitted to a medical ICU.","volume":"131","author":"Khan","year":"2007","journal-title":"Chest"},{"key":"R21-2-20210309","doi-asserted-by":"crossref","first-page":"1149","DOI":"10.1053\/j.ajkd.2003.08.015","article-title":"Plasmapheresis therapy for diffuse alveolar hemorrhage in patients with small-vessel vasculitis.","volume":"42","author":"Klemmer","year":"2003","journal-title":"Am J Kidney Dis"},{"key":"R22-2-20210309","doi-asserted-by":"crossref","first-page":"R25","DOI":"10.1186\/ar610","article-title":"Heterogeneity of CD4 and CD8+ memory T cells in localized and generalized Wegener's granulomatosis.","volume":"5","author":"Lamprecht","year":"2003","journal-title":"Arthritis Res Ther"},{"key":"R23-2-20210309","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1097\/00005792-200007000-00003","article-title":"Microscopic polyangiitis with alveolar hemorrhage. A study of 29 cases and review of the literature. Groupe d'Etudes et de Recherche sur les Maladies \"Orphelines\" Pulmonaires (GERM\"O\"P).","volume":"79","author":"Lauque","year":"2000","journal-title":"Medicine (Baltimore)"},{"key":"R24-2-20210309","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1002\/art.1780330807","article-title":"The American College of Rheumatology 1990 criteria for the classification of Wegener's granulomatosis.","volume":"33","author":"Leavitt","year":"1990","journal-title":"Arthritis Rheum"},{"key":"R25-2-20210309","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1002\/art.1780330805","article-title":"The American College of Rheumatology 1990 criteria for the classification of polyarteritis nodosa.","volume":"33","author":"Lightfoot","year":"1990","journal-title":"Arthritis Rheum"},{"key":"R26-2-20210309","first-page":"161","article-title":"Classical versus non-renal Wegener's granulomatosis.","volume":"87","author":"Luqmani","year":"1994","journal-title":"Q J Med"},{"key":"R27-2-20210309","first-page":"671","article-title":"Birmingham Vasculitis Activity Score (BVAS) in systemic necrotizing vasculitis.","volume":"87","author":"Luqmani","year":"1994","journal-title":"QJM"},{"key":"R28-2-20210309","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1093\/rheumatology\/40.5.492","article-title":"Analysis of factors predictive of survival based on 49 patients with systemic Wegener's granulomatosis and prospective follow-up.","volume":"40","author":"Mahr","year":"2001","journal-title":"Rheumatology (Oxford)"},{"key":"R29-2-20210309","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1002\/art.1780330806","article-title":"The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis).","volume":"33","author":"Masi","year":"1990","journal-title":"Arthritis Rheum"},{"key":"R30-2-20210309","first-page":"2488","article-title":"Current status of outcome measures in vasculitis: focus on Wegener's granulomatosis and microscopic polyangiitis. Report from OMERACT 7.","volume":"32","author":"Merkel","year":"2005","journal-title":"J Rheumatol"},{"key":"R31-2-20210309","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1097\/00005792-200201000-00002","article-title":"Polyarteritis nodosa and Churg-Strauss angiitis: characteristics and outcome in 38 patients over 65 years.","volume":"81","author":"Mouthon","year":"2002","journal-title":"Medicine (Baltimore)"},{"key":"R32-2-20210309","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1136\/ard.2007.071936","article-title":"Outcomes from studies of antineutrophil cytoplasm antibody associated vasculitis: a systematic review by the European League Against Rheumatism systemic vasculitis task force.","volume":"67","author":"Mukhtyar","year":"2008","journal-title":"Ann Rheum Dis"},{"key":"R33-2-20210309","doi-asserted-by":"crossref","first-page":"2790","DOI":"10.1056\/NEJMoa0802311","article-title":"Azathioprine or methotrexate maintenance for ANCA-associated vasculitis.","volume":"359","author":"Pagnoux","year":"2008","journal-title":"N Engl J Med"},{"key":"R34-2-20210309","doi-asserted-by":"crossref","first-page":"1186","DOI":"10.1002\/art.27340","article-title":"Treatment of polyarteritis nodosa and microscopic polyangiitis without poor-prognosis factors: a prospective randomized study of one hundred twenty-four patients.","volume":"62","author":"Ribi","year":"2010","journal-title":"Arthritis Rheum"},{"key":"R35-2-20210309","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1002\/art.23198","article-title":"Treatment of Churg-Strauss syndrome without poor-prognosis factors: a multicenter, prospective, randomized, open-label study of seventy-two patients.","volume":"58","author":"Ribi","year":"2008","journal-title":"Arthritis Rheum"},{"key":"R36-2-20210309","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1002\/1529-0131(200104)44:4<912::AID-ANR148>3.0.CO;2-5","article-title":"A disease-specific activity index for Wegener's granulomatosis: modification of the Birmingham Vasculitis Activity Score. International Network for the Study of the Systemic Vasculitides (INSSYS).","volume":"44","author":"Stone","year":"2001","journal-title":"Arthritis Rheum"}],"container-title":["Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/MD.0b013e318205a4c6","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T16:26:37Z","timestamp":1786033597000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/00005792-201101000-00002"}},"subtitle":["Assessment of Prognoses of Systemic Necrotizing Vasculitides Based on the French Vasculitis Study Group (FVSG) Cohort"],"short-title":[],"issued":{"date-parts":[[2011,1]]},"references-count":36,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2011]]}},"URL":"https:\/\/doi.org\/10.1097\/md.0b013e318205a4c6","relation":{},"ISSN":["0025-7974"],"issn-type":[{"value":"0025-7974","type":"print"}],"subject":[],"published":{"date-parts":[[2011,1]]}}}