{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T16:21:06Z","timestamp":1786119666886,"version":"build-2736575974"},"reference-count":56,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Current Opinion in Endocrinology, Diabetes and Obesity"],"published-print":{"date-parts":[[2009,2]]},"DOI":"10.1097\/med.0b013e328320a821","type":"journal-article","created":{"date-parts":[[2011,1,14]],"date-time":"2011-01-14T01:55:31Z","timestamp":1294970131000},"page":"60-65","source":"Crossref","is-referenced-by-count":13,"title":["Sonic hedgehog in gastric physiology and neoplastic transformation: friend or foe?"],"prefix":"10.1097","volume":"16","author":[{"given":"Mohamad","family":"El-Zaatari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Milena","family":"Saqui-Salces","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megna","family":"Waghray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Todisco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juanita L","family":"Merchant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-12-20110114","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/S0140-6736(75)90498-5","volume":"2","author":"Correa","year":"1975","journal-title":"Lancet"},{"key":"R2-12-20110114","doi-asserted-by":"crossref","first-page":"2763","DOI":"10.1242\/dev.127.12.2763","volume":"127","author":"Ramalho-Santos","year":"2000","journal-title":"Development"},{"key":"R3-12-20110114","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1002\/dvdy.20542","volume":"234","author":"Kim","year":"1005","journal-title":"Dev Dyn"},{"key":"R4-12-20110114","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1038\/nature01972","volume":"425","author":"Berman","year":"2003","journal-title":"Nature"},{"key":"R5-12-20110114","doi-asserted-by":"crossref","first-page":"10822","DOI":"10.1158\/0008-5472.CAN-05-0777","volume":"65","author":"Ohta","year":"2005","journal-title":"Cancer Res"},{"key":"R6-12-20110114","doi-asserted-by":"crossref","first-page":"1698","DOI":"10.1093\/carcin\/bgi130","volume":"26","author":"Ma","year":"2005","journal-title":"Carcinogenesis"},{"key":"R7-12-20110114","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.bbr.2006.07.022","volume":"174","author":"Umehara","year":"2006","journal-title":"Behav Brain Res"},{"key":"R8-12-20110114","doi-asserted-by":"crossref","first-page":"G99","DOI":"10.1152\/ajpgi.00389.2007","volume":"295","author":"Zavros","year":"2008","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"key":"R9-12-20110114","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.regpep.2007.09.020","volume":"146","author":"El-Zaatari","year":"2008","journal-title":"Regul Pept"},{"key":"R10-12-20110114","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1053\/gast.2001.26261","volume":"121","author":"Van den Brink","year":"2001","journal-title":"Gastoenterology"},{"key":"R11-12-20110114","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1053\/j.gastro.2006.05.008","volume":"131","author":"Fukaya","year":"2006","journal-title":"Gastroenterology"},{"key":"R12-12-20110114","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1038\/nrm2414","volume":"9","author":"Eaton","year":"2008","journal-title":"Nat Rev Mol Cell Biol"},{"key":"R13-12-20110114","doi-asserted-by":"crossref","first-page":"1855","DOI":"10.1038\/sj.bjc.6603782","volume":"96","author":"El-Zaatari","year":"2007","journal-title":"Br J Cancer"},{"key":"R14-12-20110114","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1242\/dev.01576","volume":"132","author":"Madison","year":"2005","journal-title":"Development"},{"key":"R15-12-20110114","doi-asserted-by":"crossref","first-page":"2458","DOI":"10.4161\/cc.6.20.4808","volume":"6","author":"Lauth","year":"2007","journal-title":"Cell Cycle"},{"key":"R16-12-20110114","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1159\/000134271","volume":"8","author":"Fern\u00e1ndez-Zapico","year":"2008","journal-title":"Pancreatology"},{"key":"R17-12-20110114","doi-asserted-by":"crossref","first-page":"15700","DOI":"10.1074\/jbc.M413037200","volume":"280","author":"Stepan","year":"2005","journal-title":"J Biol Chem"},{"key":"R18-12-20110114","first-page":"A574","volume":"134","author":"Zavros","year":"2008","journal-title":"Gastroenterology"},{"key":"R19-12-20110114","doi-asserted-by":"crossref","first-page":"1829","DOI":"10.1097\/01.LAB.0000101729.25140.0C","volume":"83","author":"Dimmler","year":"2003","journal-title":"Lab Invest"},{"key":"R20-12-20110114","doi-asserted-by":"crossref","first-page":"33265","DOI":"10.1074\/jbc.M707090200","volume":"282","author":"Zavros","year":"2007","journal-title":"J Biol Chem"},{"key":"R21-12-20110114","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1073\/pnas.0705603105","volume":"105","author":"Callejo","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R22-12-20110114","doi-asserted-by":"crossref","first-page":"25660","DOI":"10.1074\/jbc.M201933200","volume":"277","author":"McCarthy","year":"2002","journal-title":"J Biol Chem"},{"key":"R23-12-20110114","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1101\/gad.1185804","volume":"18","author":"Chen","year":"2004","journal-title":"Genes Dev"},{"key":"R24-12-20110114","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1038\/nature07275","volume":"455","author":"Yauch","year":"2008","journal-title":"Nature"},{"key":"R25-12-20110114","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/384129a0","volume":"384","author":"Stone","year":"1996","journal-title":"Nature"},{"key":"R26-12-20110114","doi-asserted-by":"crossref","first-page":"e53","DOI":"10.1371\/journal.pgen.0010053","volume":"1","author":"Haycraft","year":"2005","journal-title":"PLoS Genet"},{"key":"R27-12-20110114","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1016\/j.devcel.2007.03.004","volume":"12","author":"Caspary","year":"2007","journal-title":"Dev Cell"},{"key":"R28-12-20110114","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1038\/ng.105","volume":"40","author":"Tran","year":"2008","journal-title":"Nat Genet"},{"key":"R29-12-20110114","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1126\/science.1124534","volume":"313","author":"Singla","year":"2006","journal-title":"Science"},{"key":"R30-12-20110114","doi-asserted-by":"crossref","first-page":"462","DOI":"10.1016\/j.cellbi.2008.03.001","volume":"32","author":"Bell","year":"2008","journal-title":"Cell Biol Int"},{"key":"R31-12-20110114","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/S0306-4522(98)00354-6","volume":"89","author":"H\u00e4ndel","year":"1999","journal-title":"Neuroscience"},{"key":"R32-12-20110114","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1126\/science.1139740","volume":"317","author":"Rohatgi","year":"2007","journal-title":"Science"},{"key":"R33-12-20110114","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1136\/jcp.2004.021865","volume":"58","author":"Rubio","year":"2005","journal-title":"J Clin Pathol"},{"key":"R34-12-20110114","doi-asserted-by":"crossref","first-page":"21555","DOI":"10.1074\/jbc.M001558200","volume":"275","author":"Spicer","year":"2000","journal-title":"J Biol Chem"},{"key":"R35-12-20110114","first-page":"177","volume":"61","author":"","year":"1994","journal-title":"IARC Monogr Eval Carcinog Risks Hum"},{"key":"R36-12-20110114","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1002\/path.1763","volume":"206","author":"Suzuki","year":"2005","journal-title":"J Pathol"},{"key":"R37-12-20110114","doi-asserted-by":"crossref","first-page":"1631","DOI":"10.1038\/labinvest.3700197","volume":"84","author":"Neilsen","year":"2004","journal-title":"Lab Invest"},{"key":"R38-12-20110114","doi-asserted-by":"crossref","first-page":"10074","DOI":"10.1523\/JNEUROSCI.2604-04.2004","volume":"24","author":"Lin","year":"2004","journal-title":"J Neurosci"},{"key":"R39-12-20110114","doi-asserted-by":"crossref","first-page":"7041","DOI":"10.1158\/0008-5472.CAN-05-4588","volume":"66","author":"Nakashima","year":"2006","journal-title":"Cancer Res"},{"key":"R40-12-20110114","doi-asserted-by":"crossref","first-page":"6981","DOI":"10.1158\/0008-5472.CAN-07-0491","volume":"67","author":"Dennler","year":"2007","journal-title":"Cancer Res"},{"key":"R41-12-20110114","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1016\/j.bbrc.2007.07.200","volume":"362","author":"Frandsen","year":"2007","journal-title":"Biochem Biophys Res Commun"},{"key":"R42-12-20110114","first-page":"2369","volume":"57","author":"Xie","year":"1997","journal-title":"Cancer Res"},{"key":"R43-12-20110114","doi-asserted-by":"crossref","first-page":"9255","DOI":"10.1073\/pnas.151173398","volume":"98","author":"Xie","year":"2001","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R44-12-20110114","doi-asserted-by":"crossref","first-page":"321","DOI":"10.2353\/ajpath.2006.050001","volume":"168","author":"Tiet","year":"2006","journal-title":"Am J Pathol"},{"key":"R45-12-20110114","doi-asserted-by":"crossref","first-page":"12561","DOI":"10.1073\/pnas.0404956101","volume":"101","author":"Sanchez","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R46-12-20110114","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1038\/sj.onc.1209860","volume":"15","author":"Yuan","year":"2007","journal-title":"Oncogene"},{"key":"R47-12-20110114","doi-asserted-by":"crossref","first-page":"111","DOI":"10.4161\/cbt.5.1.2379","volume":"5","author":"Patil","year":"2006","journal-title":"Cancer Biol Ther"},{"key":"R48-12-20110114","doi-asserted-by":"crossref","first-page":"665","DOI":"10.1016\/j.surg.2005.10.012","volume":"139","author":"Douard","year":"2006","journal-title":"Surgery"},{"key":"R49-12-20110114","doi-asserted-by":"crossref","first-page":"1026","DOI":"10.1038\/nrd2086","volume":"5","author":"Rubin","year":"2006","journal-title":"Nat Rev Drug Discov"},{"key":"R50-12-20110114","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1126\/science.277.5329.1109","volume":"277","author":"Goodrich","year":"1997","journal-title":"Science"},{"key":"R51-12-20110114","doi-asserted-by":"crossref","first-page":"5201","DOI":"10.1242\/dev.128.24.5201","volume":"128","author":"Dahmane","year":"2001","journal-title":"Development"},{"key":"R52-12-20110114","doi-asserted-by":"crossref","first-page":"1559","DOI":"10.1126\/science.1073733","volume":"297","author":"Berman","year":"2002","journal-title":"Science"},{"key":"R53-12-20110114","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.mcn.2004.08.004","volume":"27","author":"Wang","year":"2004","journal-title":"Mol Cell Neurosci"},{"key":"R54-12-20110114","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1038\/nature02009","volume":"425","author":"Thayer","year":"2003","journal-title":"Nature"},{"key":"R55-12-20110114","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/path.2221","volume":"213","author":"Minegishi","year":"2007","journal-title":"J Pathol"},{"key":"R56-12-20110114","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1111\/j.1572-0241.2005.41001.x","volume":"100","author":"Shiotani","year":"2005","journal-title":"Am J Gastroenterol"}],"container-title":["Current Opinion in Endocrinology, Diabetes and Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.1097\/MED.0b013e328320a821","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T18:52:59Z","timestamp":1786042379000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/01266029-200902000-00012"}},"subtitle":[""],"short-title":[],"issued":{"date-parts":[[2009,2]]},"references-count":56,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.1097\/med.0b013e328320a821","relation":{},"ISSN":["1752-296X"],"issn-type":[{"value":"1752-296X","type":"print"}],"subject":[],"published":{"date-parts":[[2009,2]]}}}