{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T05:04:41Z","timestamp":1784264681504,"version":"3.55.0"},"reference-count":50,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,2]]},"DOI":"10.1097\/med.0b013e32835b7ec7","type":"journal-article","created":{"date-parts":[[2013,8,30]],"date-time":"2013-08-30T15:57:49Z","timestamp":1377878269000},"page":"62-68","source":"Crossref","is-referenced-by-count":44,"title":["Control of puberty"],"prefix":"10.1097","volume":"20","author":[{"given":"Jin-Ho","family":"Choi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han-Wook","family":"Yoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-13-20211004","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.mce.2006.04.004","article-title":"Programming of GnRH feedback controls timing puberty and adult reproductive activity.","volume":"254-","author":"Foster","year":"2006","journal-title":"Mol Cell Endocrinol"},{"issue":"Suppl 2","key":"R2-13-20211004","first-page":"41","article-title":"Early onset of puberty: tracking genetic and environmental factors.","volume":"64","author":"Parent","year":"2005","journal-title":"Horm Res"},{"key":"R3-13-20211004","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1210\/er.2002-0019","article-title":"The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migration.","volume":"24","author":"Parent","year":"2003","journal-title":"Endocr Rev"},{"key":"R4-13-20211004","doi-asserted-by":"crossref","first-page":"2364","DOI":"10.1210\/jcem.86.6.7603","article-title":"Variation in the timing of puberty: clinical spectrum and genetic investigation.","volume":"86","author":"Palmert","year":"2001","journal-title":"J Clin Endocrinol Metab"},{"issue":"Suppl 2","key":"R5-13-20211004","first-page":"56","article-title":"Precocious puberty: growth and genetics.","volume":"64","author":"Phillip","year":"2005","journal-title":"Horm Res"},{"key":"R6-13-20211004","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.mce.2010.01.038","article-title":"Genetic determinants of pubertal timing in the general population.","volume":"324","author":"Gajdos","year":"2010","journal-title":"Mol Cell Endocrinol"},{"key":"R7-13-20211004","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1097\/MOP.0b013e3283060ed4","article-title":"Genetic control of pubertal timing.","volume":"20","author":"Kaminski","year":"2008","journal-title":"Curr Opin Pediatr"},{"key":"R8-13-20211004","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/j.mce.2009.12.003","article-title":"Gene networks and the neuroendocrine regulation of puberty.","volume":"324","author":"Ojeda","year":"2010","journal-title":"Mol Cell Endocrinol"},{"key":"R9-13-20211004","doi-asserted-by":"crossref","first-page":"1614","DOI":"10.1056\/NEJMoa035322","article-title":"The GPR54 gene as a regulator of puberty.","volume":"349","author":"Seminara","year":"2003","journal-title":"N Engl J Med"},{"key":"R10-13-20211004","doi-asserted-by":"crossref","first-page":"1154","DOI":"10.1210\/en.2005-1282","article-title":"Minireview: kisspeptin neurons as central processors in the regulation of gonadotropin-releasing hormone secretion.","volume":"147","author":"Dungan","year":"2006","journal-title":"Endocrinology"},{"key":"R11-13-20211004","doi-asserted-by":"crossref","first-page":"48","DOI":"10.3389\/fendo.2012.00048","article-title":"New insights into the control of pulsatile GnRH release: the role of kiss1neurokinin B neurons.","volume":"3","author":"Navarro","year":"2012","journal-title":"Front Endocrinol (Lausanne)"},{"key":"R12-13-20211004","doi-asserted-by":"crossref","first-page":"5147","DOI":"10.1210\/en.2007-0634","article-title":"Expression of a tumor-related gene network increases in the mammalian hypothalamus at the time of female puberty.","volume":"148","author":"Roth","year":"2007","journal-title":"Endocrinology"},{"key":"R13-13-20211004","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S1096-7192(03)00107-0","article-title":"Genetic approaches to stature, pubertal timing, and other complex traits.","volume":"80","author":"Palmert","year":"2003","journal-title":"Mol Genet Metab"},{"key":"R14-13-20211004","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1007\/s10519-005-9022-y","article-title":"Individual differences in puberty onset in girls: Bayesian estimation of heritabilities and genetic correlations.","volume":"36","author":"van den Berg","year":"2006","journal-title":"Behav Genet"},{"key":"R15-13-20211004","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1093\/humupd\/dmr050","article-title":"Genetics of age at menarche: a systematic review.","volume":"18","author":"Dvornyk","year":"2012","journal-title":"Hum Reprod Update"},{"key":"R16-13-20211004","doi-asserted-by":"crossref","first-page":"799","DOI":"10.1210\/jc.2002-020353","article-title":"Estrogen-metabolizing gene polymorphisms, but not estrogen receptor-alpha gene polymorphisms, are associated with the onset of menarche in healthy postmenopausal Japanese women.","volume":"88","author":"Gorai","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"R17-13-20211004","first-page":"327","article-title":"The CYP3A41B variant is related to the onset of puberty, a known risk factor for the development of breast cancer.","volume":"12","author":"Kadlubar","year":"2003","journal-title":"Cancer Epidemiol Biomarkers Prev"},{"key":"R18-13-20211004","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1038\/ng.383","article-title":"Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche.","volume":"41","author":"Sulem","year":"2009","journal-title":"Nat Genet"},{"key":"R19-13-20211004","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1038\/ng.382","article-title":"Genetic variation in LIN28B is associated with the timing of puberty.","volume":"41","author":"Ong","year":"2009","journal-title":"Nat Genet"},{"key":"R20-13-20211004","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1038\/ng.385","article-title":"Genome-wide association studies identify loci associated with age at menarche and age at natural menopause.","volume":"41","author":"He","year":"2009","journal-title":"Nat Genet"},{"key":"R21-13-20211004","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.mce.2011.05.019","article-title":"New genetic factors implicated in human GnRH-dependent precocious puberty: the role of kisspeptin system.","volume":"346","author":"Teles","year":"2011","journal-title":"Mol Cell Endocrinol"},{"key":"R22-13-20211004","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1186\/1756-0500-4-363","article-title":"LIN28B, LIN28A, KISS1, and KISS1R in idiopathic central precocious puberty.","volume":"4","author":"Tommiska","year":"2011","journal-title":"BMC Res Notes"},{"key":"R23-13-20211004","doi-asserted-by":"crossref","first-page":"1794","DOI":"10.1210\/jc.2003-030361","article-title":"Familial central precocious puberty suggests autosomal dominant inheritance.","volume":"89","author":"de Vries","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"R24-13-20211004","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1056\/NEJMoa073443","article-title":"A GPR54-activating mutation in a patient with central precocious puberty.","volume":"358","author":"Teles","year":"2008","journal-title":"N Engl J Med"},{"key":"R25-13-20211004","doi-asserted-by":"crossref","first-page":"2276","DOI":"10.1210\/jc.2009-2421","article-title":"Mutations of the KISS1 gene in disorders of puberty.","volume":"95","author":"Silveira","year":"2010","journal-title":"J Clin Endocrinol Metab"},{"key":"R26-13-20211004","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1750-1172-3-12","article-title":"McCune-Albright syndrome.","volume":"3","author":"Dumitrescu","year":"2008","journal-title":"Orphanet J Rare Dis"},{"key":"R27-13-20211004","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.mce.2011.07.012","article-title":"Isolated GnRH deficiency: a disease model serving as a unique prism into the systems biology of the GnRH neuronal network.","volume":"346","author":"Balasubramanian","year":"2011","journal-title":"Mol Cell Endocrinol"},{"key":"R28-13-20211004","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/ng0198-14","article-title":"Mutations in gonadotropin-releasing hormone receptor gene cause hypogonadotropic hypogonadism.","volume":"18","author":"Layman","year":"1998","journal-title":"Nat Genet"},{"key":"R29-13-20211004","doi-asserted-by":"crossref","first-page":"4290","DOI":"10.1210\/jc.2008-0981","article-title":"Association studies of common variants in 10 hypogonadotropic hypogonadism genes with age at menarche.","volume":"93","author":"Gajdos","year":"2008","journal-title":"J Clin Endocrinol Metab"},{"key":"R30-13-20211004","doi-asserted-by":"crossref","first-page":"10972","DOI":"10.1073\/pnas.1834399100","article-title":"Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54.","volume":"100","author":"de Roux","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R31-13-20211004","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.ajhg.2008.09.005","article-title":"Mutations in CHD7, encoding a chromatin-remodeling protein, cause idiopathic hypogonadotropic hypogonadism and Kallmann syndrome.","volume":"83","author":"Kim","year":"2008","journal-title":"Am J Hum Genet"},{"key":"R32-13-20211004","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1055\/s-2002-36707","article-title":"Hypogonadotropic hypogonadism.","volume":"20","author":"Silveira","year":"2002","journal-title":"Semin Reprod Med"},{"key":"R33-13-20211004","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1172\/JCI29884","article-title":"Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism.","volume":"117","author":"Pitteloud","year":"2007","journal-title":"J Clin Invest"},{"key":"R34-13-20211004","doi-asserted-by":"crossref","first-page":"15140","DOI":"10.1073\/pnas.1009622107","article-title":"Oligogenic basis of isolated gonadotropin-releasing hormone deficiency.","volume":"107","author":"Sykiotis","year":"2010","journal-title":"Proc Natl Acad Sci U S A"},{"key":"R35-13-20211004","doi-asserted-by":"crossref","first-page":"863","DOI":"10.1056\/NEJMoa066494","article-title":"Reversal of idiopathic hypogonadotropic hypogonadism.","volume":"357","author":"Raivio","year":"2007","journal-title":"N Engl J Med"},{"issue":"Suppl 2","key":"R36-13-20211004","first-page":"2","article-title":"The neuroendocrinology of human puberty revisited.","volume":"57","author":"Grumbach","year":"2002","journal-title":"Horm Res"},{"key":"R37-13-20211004","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1111\/j.1365-2605.2005.00619.x","article-title":"Neuroendocrine mechanisms controlling female puberty: new approaches, new concepts.","volume":"29","author":"Ojeda","year":"2006","journal-title":"Int J Androl"},{"key":"R38-13-20211004","doi-asserted-by":"crossref","first-page":"2145","DOI":"10.1172\/JCI31752","article-title":"Enhanced at puberty 1 (EAP1) is a new transcriptional regulator of the female neuroendocrine reproductive axis.","volume":"117","author":"Heger","year":"2007","journal-title":"J Clin Invest"},{"key":"R39-13-20211004","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1016\/j.brainres.2010.09.039","article-title":"The transcriptional control of female puberty.","volume":"1364","author":"Ojeda","year":"2010","journal-title":"Brain Res"},{"key":"R40-13-20211004","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1038\/ng.306","article-title":"TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction.","volume":"41","author":"Topaloglu","year":"2009","journal-title":"Nat Genet"},{"key":"R41-13-20211004","doi-asserted-by":"crossref","first-page":"11859","DOI":"10.1523\/JNEUROSCI.1569-09.2009","article-title":"Regulation of gonadotropin-releasing hormone secretion by kisspeptindynorphinneurokinin B neurons in the arcuate nucleus of the mouse.","volume":"29","author":"Navarro","year":"2009","journal-title":"J Neurosci"},{"key":"R42-13-20211004","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1002\/ajhb.20508","article-title":"Family composition and menarcheal age: antiinbreeding strategies.","volume":"18","author":"Matchock","year":"2006","journal-title":"Am J Hum Biol"},{"key":"R43-13-20211004","doi-asserted-by":"crossref","first-page":"264","DOI":"10.1111\/j.1365-2605.2005.00561.x","article-title":"Endocrine disrupters and human puberty.","volume":"29","author":"Den Hond","year":"2006","journal-title":"Int J Androl"},{"key":"R44-13-20211004","doi-asserted-by":"crossref","first-page":"E72","DOI":"10.1542\/peds.106.5.e72","article-title":"Early puberty: rapid progression and reduced final height in girls with low birth weight.","volume":"106","author":"Ibanez","year":"2000","journal-title":"Pediatrics"},{"key":"R45-13-20211004","doi-asserted-by":"crossref","first-page":"4369","DOI":"10.1210\/jc.2006-0953","article-title":"Opposing influences of prenatal and postnatal growth on the timing of menarche.","volume":"91","author":"Tam","year":"2006","journal-title":"J Clin Endocrinol Metab"},{"key":"R46-13-20211004","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1016\/j.mce.2006.04.003","article-title":"Early and late weight gain and the timing of puberty.","volume":"254-","author":"Dunger","year":"2006","journal-title":"Mol Cell Endocrinol"},{"key":"R47-13-20211004","doi-asserted-by":"crossref","first-page":"1696","DOI":"10.1210\/en.2011-1970","article-title":"Body weight impact on puberty: effects of high-calorie diet on puberty onset in female rhesus monkeys.","volume":"153","author":"Terasawa","year":"2012","journal-title":"Endocrinology"},{"key":"R48-13-20211004","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1359\/jbmr.2002.17.6.1034","article-title":"Leptin acts as a growth factor on the chondrocytes of skeletal growth centers.","volume":"17","author":"Maor","year":"2002","journal-title":"J Bone Miner Res"},{"key":"R49-13-20211004","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1159\/000054666","article-title":"A reassessment of leptins role in triggering the onset of puberty in the rat and mouse.","volume":"74","author":"Cheung","year":"2001","journal-title":"Neuroendocrinology"},{"key":"R50-13-20211004","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1093\/humrep\/16.5.1020","article-title":"Sexual precocity after immigration from developing countries to Belgium: evidence of previous exposure to organochlorine pesticides.","volume":"16","author":"Krstevska-Konstantinova","year":"2001","journal-title":"Hum Reprod"}],"container-title":["Current Opinion in Endocrinology, Diabetes & Obesity"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/01266029-201302000-00013","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,10,4]],"date-time":"2021-10-04T02:27:36Z","timestamp":1633314456000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/01266029-201302000-00013"}},"subtitle":["genetics, endocrinology, and environment"],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":50,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1097\/med.0b013e32835b7ec7","relation":{},"ISSN":["1752-296X"],"issn-type":[{"value":"1752-296X","type":"print"}],"subject":[],"published":{"date-parts":[[2013,2]]}}}