{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T08:16:52Z","timestamp":1789546612089,"version":"build-2803163510"},"reference-count":49,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2013,7]]},"DOI":"10.1097\/mjt.0b013e318235f190","type":"journal-article","created":{"date-parts":[[2012,9,28]],"date-time":"2012-09-28T07:17:55Z","timestamp":1348816675000},"page":"442-447","source":"Crossref","is-referenced-by-count":7,"title":["Approach to a Successful Selection of Antihypertensive Drugs for the Patient With Atherosclerosis"],"prefix":"10.1097","volume":"20","author":[{"given":"Manuel","family":"Velasco","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edward","family":"Rojas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valmore B.","family":"Pirela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-18-20210202","doi-asserted-by":"crossref","first-page":"2746","DOI":"10.1161\/hc4601.099487","article-title":". Global burden of cardiovascular diseases: part I: general considerations, the epidemiological transition, risk factors, and impact of urbanization.","volume":"104","author":"Yusuf","year":"2001","journal-title":"Circulation"},{"key":"R3-18-20210202","doi-asserted-by":"crossref","first-page":"1206","DOI":"10.1161\/01.HYP.0000107251.49515.c2","article-title":". Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure.","volume":"42","author":"Chobanian","year":"2003","journal-title":"Hypertension"},{"key":"R4-18-20210202","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1161\/01.CIR.104.3.365","article-title":"Current concepts of the pathogenesis of the acute coronary syndromes.","volume":"104","author":"Libby","year":"2001","journal-title":"Circulation"},{"key":"R5-18-20210202","doi-asserted-by":"crossref","first-page":"1685","DOI":"10.1056\/NEJMra043430","article-title":"Inflammation, atherosclerosis, and coronary artery disease.","volume":"352","author":"Hansson","year":"2005","journal-title":"N Engl J Med"},{"key":"R6-18-20210202","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1093\/cvr\/cvp333","article-title":"On to the road to degradation: atherosclerosis and the proteasome.","volume":"85","author":"Herrmann","year":"2010","journal-title":"Cardiovasc Res"},{"key":"R7-18-20210202","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1093\/cvr\/cvp363","article-title":". Control of cell proliferation in atherosclerosis: insights from animal models and human studies.","volume":"86","author":"Fuster","year":"2010","journal-title":"Cardiovas Res"},{"key":"R8-18-20210202","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1093\/cvr\/cvp391","article-title":"Chemokines in the vascular inflammatory response of atherosclerosis.","volume":"86","author":"Zernecke","year":"2010","journal-title":"Cardiovas Res"},{"key":"R9-18-20210202","doi-asserted-by":"crossref","first-page":"2292","DOI":"10.1161\/ATVBAHA.107.149179","article-title":"Vascular adhesion molecules in atherosclerosis.","volume":"27","author":"Galkina","year":"2007","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"R10-18-20210202","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1093\/eurheartj\/ehn515","article-title":". Homocysteine and coronary atherosclerosis: from folate fortification to the recent clinical trials.","volume":"30","author":"Antoniades","year":"2009","journal-title":"Eur Heart J"},{"key":"R11-18-20210202","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1161\/01.ATV.0000105054.43931.f0","article-title":"Site specificity of atherosclerosis: site-selective responses to atherosclerotic modulators.","volume":"24","author":"VanderLaan","year":"2004","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"R12-18-20210202","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1001\/archinte.1996.00440160064009","article-title":"Exacerbation of atherosclerosis by hypertension: potential mechanisms and clinical implications.","volume":"156","author":"Chobanian","year":"1996","journal-title":"Arch Intern Med"},{"key":"R13-18-20210202","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1161\/01.HYP.32.2.338","article-title":"Signal transduction of mechanical stresses in the vascular wall.","volume":"32","author":"Lehoux","year":"1998","journal-title":"Hypertension"},{"key":"R14-18-20210202","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.cardiores.2006.05.008","article-title":"Redox signalling in vascular responses to shear and stretch.","volume":"71","author":"Lehoux","year":"2006","journal-title":"Cardiovasc Res"},{"key":"R17-18-20210202","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1093\/cvr\/cvp179","article-title":"Ultrasound molecular imaging of atherosclerosis.","volume":"83","author":"Kaufmann","year":"2009","journal-title":"Cardiovasc Res"},{"key":"R18-18-20210202","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1161\/CIRCIMAGING.108.786962","article-title":". Evaluation of coronary atherosclerosis by multislice computed tomography in patients with acute myocardial infarction and without significant coronary artery stenosis a comparative study with quantitative coronary angiography.","volume":"1","author":"Aldrovandi","year":"2008","journal-title":"Circ Cardiovasc Imaging"},{"key":"R19-18-20210202","doi-asserted-by":"crossref","first-page":"1310","DOI":"10.2337\/diacare.23.9.1310","article-title":". Carotid intima-media thickness in Japanese type 2 diabetic subjects: predictors of progression and relationship with incident coronary heart disease.","volume":"23","author":"Yamasaki","year":"2000","journal-title":"Diabetes Care"},{"key":"R20-18-20210202","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1161\/01.STR.32.7.1532","article-title":". Is carotid intima-media thickness useful in cardiovascular disease risk assessment The Rotterdam Study.","volume":"32","author":"del Sol","year":"2001","journal-title":"Stroke"},{"key":"R21-18-20210202","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1093\/oxfordjournals.aje.a010233","article-title":". Carotid wall thickness is predictive of incident clinical stroke: the Atherosclerosis Risk in Communities (ARIC) study.","volume":"151","author":"Chambless","year":"2000","journal-title":"Am J Epidemiol"},{"key":"R22-18-20210202","doi-asserted-by":"crossref","first-page":"1940","DOI":"10.1161\/01.CIR.82.6.1940","article-title":". A controlled clinical trial to assess the effect of a calcium channel blocker on the progression of coronary atherosclerosis.","volume":"82","author":"Waters","year":"1990","journal-title":"Circulation"},{"key":"R23-18-20210202","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1056\/NEJM199301213280303","article-title":". A preliminary study of diltiezem in the prevention of coronary artery disease in heart-transplant recipients.","volume":"328","author":"Schroeder","year":"1993","journal-title":"N Engl J Med"},{"key":"R24-18-20210202","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1001\/jama.1996.03540100029024","article-title":". Final outcome results of the Multicenter Isradipine Diuretic Atherosclerosis Study (MIDAS). A randomized controlled trial.","volume":"276","author":"Borhani","year":"1996","journal-title":"JAMA"},{"key":"R25-18-20210202","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1097\/00004872-199816110-00014","article-title":". The Verapamil in Hypertension and Atherosclerosis Study (VHAS): results of long-term randomized treatment with either verapamil or chlorthalidone on carotid intima-media thickness.","volume":"16","author":"Zanchetti","year":"1998","journal-title":"J Hypertens"},{"key":"R26-18-20210202","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1161\/01.CIR.102.13.1503","article-title":". Effect of amlodipine on the progression of atherosclerosis and the occurrence of clinical events.","volume":"102","author":"Pitt","year":"2000","journal-title":"Circulation"},{"key":"R27-18-20210202","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1161\/01.CIR.103.24.2949","article-title":". Differential effects of nifedipine and co-aAmilozide on the progression of early carotid wall changes.","volume":"103","author":"Simon","year":"2001","journal-title":"Circulation"},{"key":"R28-18-20210202","doi-asserted-by":"crossref","first-page":"2422","DOI":"10.1161\/01.CIR.0000039288.86470.DD","article-title":". Calcium antagonist lacidipine slows down progression of asymptomatic carotid atherosclerosis: principal results of the European Lacidipine Study on Atherosclerosis (ELSA), a randomized, doubleblind, long-term trial.","volume":"106","author":"Zanchetti","year":"2002","journal-title":"Circulation"},{"key":"R29-18-20210202","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1161\/01.HYP.0000057420.27692.AD","article-title":". Outcomes with nifedipine GITS or Co-amilozide in hypertensive diabetics and nondiabetics in Intervention as a Goal in Hypertension (INSIGHT).","volume":"41","author":"Mancia","year":"2003","journal-title":"Hypertension"},{"key":"R30-18-20210202","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1161\/ATVBAHA.109.196980","article-title":"The value of carotid intima-media thickness for predicting cardiovascular risk.","volume":"30","author":"Simon","year":"2010","journal-title":"Arterioscler Thromb Vasc Biol"},{"key":"R31-18-20210202","doi-asserted-by":"crossref","first-page":"2985","DOI":"10.1161\/01.STR.0000102044.27905.B5","article-title":". Carotid intima-media thickness measurements in intervention studies: design options, progression rates, and sample size considerations: a point of view.","volume":"34","author":"Bots","year":"2003","journal-title":"Stroke"},{"key":"R32-18-20210202","doi-asserted-by":"crossref","first-page":"2041","DOI":"10.1093\/eurheartj\/ehq189","article-title":". Is carotid intima media thickness useful for individual prediction of cardiovascular risk Ten-year results from the Carotid Atherosclerosis Progression Study (CAPS).","volume":"31","author":"Lorenz","year":"2010","journal-title":"Eur Heart J"},{"key":"R33-18-20210202","doi-asserted-by":"crossref","first-page":"995","DOI":"10.1016\/S0140-6736(02)08089-3","article-title":". Cardiovascular morbidity and mortality in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomized trial against atenolol.","volume":"359","author":"Dahlof","year":"2002","journal-title":"Lancet"},{"key":"R34-18-20210202","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1080\/08037050510034185","article-title":". Losartan but not atenolol reduce carotid artery hypertrophy in essential hypertension. A LIFE substudy.","volume":"14","author":"Olsen","year":"2005","journal-title":"Blood Press"},{"key":"R35-18-20210202","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1097\/HJH.0b013e32831daf96","article-title":". Effects of losartan compared with atenolol on lipids in patients with hypertension and left ventricular hypertrophy: the Losartan Intervention For Endpoint reduction in hypertension study.","volume":"27","author":"Olsen","year":"2009","journal-title":"J Hypertens"},{"key":"R36-18-20210202","doi-asserted-by":"crossref","first-page":"175","DOI":"10.2147\/VHRM.S3409","article-title":". Effects of candesartan cilexetil on carotid remodeling in hypertensive diabetic patients: the MITEC study.","volume":"5","author":"Baguet","year":"2009","journal-title":"Vasc Health Risk Manag"},{"key":"R37-18-20210202","first-page":"362","article-title":". Comparative effects of AT1-antagonism and angiotensin-converting enzyme inhibition on markers of inflammation and platelet aggregation in patients with coronary artery disease.","volume":"2004","author":"Schieffer","year":"44","journal-title":"J Am Coll Cardiol"},{"key":"R38-18-20210202","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.jacc.2005.09.055","article-title":". The effect of valsartan, captopril, or both on atherosclerotic events after acute myocardial infarction. An analysis of the Valsartan in Acute Myocardial Infarction Trial (VALIANT).","volume":"47","author":"McMurray","year":"2006","journal-title":"J Am Coll Cardiol"},{"key":"R39-18-20210202","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1016\/j.jacc.2009.09.062","article-title":". Impact of olmesartan on progression of coronary atherosclerosis. A serial volumetric intravascular ultrasound analysis from the OLIVUS (Impact of Olmesarten on progression of coronary atherosclerosis: evaluation by intravascular ultrasound) trial.","volume":"55","author":"Hirohata","year":"2010","journal-title":"J Am Coll Cardiol"},{"key":"R40-18-20210202","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1177\/1753944707085982","article-title":". Carotid intima-media thickness and plaque volume changes following 2-year angiotensin II-receptor blockade. The Multicentre Olmesartan atherosclerosis Regression Evaluation (MORE) study.","volume":"1","author":"Stumpe","year":"2007","journal-title":"Ther Adv Cardiovasc Dis"},{"key":"R41-18-20210202","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1016\/S0735-1097(00)01138-4","article-title":". Irbesartan, an angiotensin type 1 receptor inhibitor, regulates markers of inflammation in patients with premature atherosclerosis.","volume":"37","author":"Navalkar","year":"2001","journal-title":"J Am Coll Cardiol"},{"key":"R42-18-20210202","doi-asserted-by":"crossref","first-page":"1536","DOI":"10.1161\/01.CIR.0000124061.78478.94","article-title":". Irbesartan but not amlodipine suppresses diabetes-associated atherosclerosis.","volume":"109","author":"Candido","year":"2004","journal-title":"Circulation"},{"key":"R43-18-20210202","doi-asserted-by":"crossref","first-page":"2217","DOI":"10.1001\/jama.292.18.2217","article-title":". Effect of antihypertensive agents on cardiovascular events in patients with coronary disease and normal blood pressure: the CAMELOT study: a randomized controlled trial.","volume":"292","author":"Nissen","year":"2004","journal-title":"JAMA"},{"key":"R44-18-20210202","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1161\/HYPERTENSIONAHA.108.114488","article-title":"Aliskiren improves nitric oxide bioavailability and limits atherosclerosis.","volume":"52","author":"Verma","year":"2008","journal-title":"Hypertension"},{"key":"R45-18-20210202","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1161\/HYPERTENSIONAHA.108.111120","article-title":". Renin inhibitor aliskiren improves impaired nitric oxide bioavailability and protects against atherosclerotic changes.","volume":"52","author":"Imanishi","year":"2008","journal-title":"Hypertension"},{"key":"R46-18-20210202","first-page":"538","article-title":"Atherosclerosis in persons with hypertension and diabetes mellitus.","volume":"18","author":"Robertson","year":"1968","journal-title":"Lab Invest"},{"key":"R47-18-20210202","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1161\/01.RES.2.3.243","article-title":"Development of atherosclerosis in dogs with hypercholesterolemia and chronic hypertension.","volume":"2","author":"Moss","year":"1954","journal-title":"Circ Res"},{"key":"R48-18-20210202","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/path.1700680214","article-title":"The relationship between experimental hypertension and cholesterol-induced atheroma in rabbits.","volume":"68","author":"Bronte-Stewart","year":"1954","journal-title":"J Pathol Bacteriol"},{"key":"R49-18-20210202","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1084\/jem.107.4.581","article-title":". Blood pressure, cholesterol content of serum and tissue, and atherogenesis in the rat.","volume":"107","author":"Deming","year":"1958","journal-title":"J Exp Med"},{"key":"R50-18-20210202","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/0002-9343(69)90024-2","article-title":"Hypertension and atherosclerosis.","volume":"46","author":"Freis","year":"1969","journal-title":"Am J Med"},{"key":"R51-18-20210202","first-page":"84","article-title":"Pathogenesis of the intimal thickenings produced by hypertension in large arteries in the rat.","volume":"19","author":"Still","year":"1968","journal-title":"Lab Invest"},{"key":"R52-18-20210202","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1093\/clinchem\/24.12.2081","article-title":"Relation of hypertension, lipids, and lipoproteins to atherosclerosis.","volume":"24","author":"Lewis","year":"1978","journal-title":"Clin Chem"}],"container-title":["American Journal of Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.lww.com\/00045391-201307000-00018","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,10]],"date-time":"2021-04-10T06:42:27Z","timestamp":1618036947000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00045391-201307000-00018"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,7]]},"references-count":49,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2013]]}},"URL":"https:\/\/doi.org\/10.1097\/mjt.0b013e318235f190","relation":{},"ISSN":["1075-2765"],"issn-type":[{"value":"1075-2765","type":"print"}],"subject":[],"published":{"date-parts":[[2013,7]]}}}