{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:10:10Z","timestamp":1777435810269,"version":"3.51.4"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2014,7]]},"DOI":"10.1097\/mjt.0b013e31824c407d","type":"journal-article","created":{"date-parts":[[2012,8,25]],"date-time":"2012-08-25T06:44:41Z","timestamp":1345877081000},"page":"e106-e109","source":"Crossref","is-referenced-by-count":22,"title":["Severe Propylene Glycol Toxicity Secondary to Use of Anti-Epileptics"],"prefix":"10.1097","volume":"21","author":[{"given":"Unnikrishnan","family":"Pillai","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jatinder C.","family":"Hothi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeenat Y.","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"276","reference":[{"key":"R1-17-20210202","doi-asserted-by":"crossref","first-page":"1432","DOI":"10.1093\/ndt\/gfq829","article-title":". An extreme and life-threatening case of recurrent D-lactate encephalopathy.","volume":"26","author":"Htyte","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"R2-17-20210202","first-page":"857","article-title":"Hyperosmolar metabolic acidosis and intravenous lorazepam.","volume":"347","author":"Mullins","year":"2003","journal-title":"N Engl J Med"},{"key":"R3-17-20210202","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1097\/00003246-200201000-00020","article-title":". Clinical practice guide lines for the sustained use of sedatives and analgesics in the critically ill adult.","volume":"30","author":"Jacobi","year":"2002","journal-title":"Crit Care Med"},{"key":"R4-17-20210202","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1097\/00003246-198705000-00021","article-title":"Propylene glycol intoxication and nitroglycerin therapy.","volume":"15","author":"Demey","year":"1987","journal-title":"Crit Care Med"},{"key":"R5-17-20210202","doi-asserted-by":"crossref","first-page":"2297","DOI":"10.1001\/archinte.1991.00400110137026","article-title":"A case of propylene glycol toxic reaction associated with etomidate infusion.","volume":"151","author":"Bedichek","year":"1991","journal-title":"Arch Intern Med"},{"key":"R6-17-20210202","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/S0272-6386(97)90577-1","article-title":". Propylene glycol-induced proximal renal tubular cell injury.","volume":"30","author":"Yorgin","year":"1997","journal-title":"Am J Kidney Dis"},{"key":"R7-17-20210202","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1007\/s12028-008-9065-z","article-title":"Propylene glycol toxicity complicating use of barbiturate coma.","volume":"9","author":"Bledsoe","year":"2008","journal-title":"Neurocrit Care"},{"key":"R8-17-20210202","doi-asserted-by":"crossref","first-page":"1140","DOI":"10.1592\/phco.21.13.1140.34611","article-title":"Short-term lorazepam infusion and concern for propylene glycol toxicity: case report and review.","volume":"21","author":"Cawley","year":"2001","journal-title":"Pharmacotherapy"},{"key":"R10-17-20210202","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1038\/ncpneph0573","article-title":". Acute kidney injury, hyperosmolality and metabolic acidosis associated with lorazepam.","volume":"3","author":"Zar","year":"2007","journal-title":"Nat Clin Pract Nephrol"},{"key":"R11-17-20210202","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1097\/01.CCM.0000134831.40466.39","article-title":". Relationship of continuous infusion lorazepam to serum propylene glycol concentration in critically ill adults.","volume":"32","author":"Arroliga","year":"2004","journal-title":"Crit Care Med"},{"key":"R12-17-20210202","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1006\/faat.1994.1076","article-title":"Acute toxicity of propylene glycol: an assessment using cultured proximal tubule cells of human origin.","volume":"23","author":"Morshed","year":"1994","journal-title":"Fundam Appl Toxicol"},{"key":"R13-17-20210202","doi-asserted-by":"crossref","first-page":"1732","DOI":"10.1345\/aph.1G083","article-title":". Propylene glycol-induced lactic acidosis in a patient with normal renal function: a proposed mechanism and monitoring, recommendations.","volume":"39","author":"Neale","year":"2005","journal-title":"Ann Pharmacother"},{"key":"R14-17-20210202","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1097\/00003246-198705000-00021","article-title":"Propylene glycol intoxication and nitroglycerin therapy.","volume":"15","author":"Demey","year":"1987","journal-title":"Crit Care Med"},{"key":"R15-17-20210202","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1056\/NEJM200009143431115","article-title":"Propylene glycol toxicity.","volume":"343","author":"Wilson","year":"2000","journal-title":"N Engl J Med"},{"key":"R16-17-20210202","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1111\/j.1525-139X.2007.00280.x","article-title":"Recognition, treatment, and prevention of propylene glycol toxicity.","volume":"20","author":"Zar","year":"2007","journal-title":"Semin Dial"},{"key":"R17-17-20210202","doi-asserted-by":"crossref","first-page":"1674","DOI":"10.1378\/chest.128.3.1674","article-title":". Propyleneglycol toxicity: a severe iatrogenic illness in ICU patients receiving IV benzodiazepines: a case series an prospective, observational pilot study.","volume":"128","author":"Wilson","year":"2005","journal-title":"Chest"},{"key":"R18-17-20210202","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1592\/phco.23.10.1094.32762","article-title":". Propylene glycol associated renal toxicity from lorazepam infusion.","volume":"23","author":"Yaucher","year":"2003","journal-title":"Pharmacotherapy"}],"container-title":["American Journal of Therapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.lww.com\/10.1097\/MJT.0b013e31824c407d","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,5,14]],"date-time":"2021-05-14T03:37:02Z","timestamp":1620963422000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.lww.com\/00045391-201407000-00017"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.1097\/mjt.0b013e31824c407d","relation":{},"ISSN":["1075-2765"],"issn-type":[{"value":"1075-2765","type":"print"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}