{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T08:13:02Z","timestamp":1787645582869,"version":"build-2736575974"},"reference-count":20,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[2009,1,2]],"date-time":"2009-01-02T00:00:00Z","timestamp":1230854400000},"content-version":"vor","delay-in-days":581,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Laryngoscope"],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p><jats:bold>Study Objectives<\/jats:bold>: To evaluate the prognosis of mild obstructive sleep apnea in relation to different treatment modalities.<\/jats:p><jats:p><jats:bold>Study Design<\/jats:bold>: An open, retrospective, longitudinal follow\u2010up study.<\/jats:p><jats:p><jats:bold>Methods<\/jats:bold>: Fifty adult patients diagnosed and treated for mild obstructive sleep apnea at the Department of Otorhinolaryngology at Kuopio University Hospital between 1998 and 2004 had a control polysomnography in 2005. The changes in apnea\u2010hypopnea index (AHI) were observed in untreated (n = 28), operative (n = 11), and continuous positive airway pressure (n = 11) treatment groups at a long\u2010term follow\u2010up visit.<\/jats:p><jats:p><jats:bold>Results<\/jats:bold>: The mean follow\u2010up period was 4 (range, 1.3\u20139.0; SD, 1.9) years. The untreated patients had a statistically significant increase in AHI (13.3, SD 18.3) at the follow\u2010up. Half of these patients developed a moderate or severe degree of sleep apnea, and only 11% were cured. In patients who were treated with continuous positive airway pressure, the degree of obstructive sleep apnea became worse in 64% of cases, and in 27% of patients, the AHI returned to normal (&lt;5). The degree of obstructive sleep apnea in operated patients deteriorated only in 18%, and in 27% of the patients, the AHI returned to normal (&lt;5).<\/jats:p><jats:p><jats:bold>Conclusions<\/jats:bold>: Mild obstructive sleep apnea has a natural tendency to worsen with time. Active treatment of mild obstructive sleep apnea appears, therefore, to be advisable.<\/jats:p>","DOI":"10.1097\/mlg.0b013e3180514d08","type":"journal-article","created":{"date-parts":[[2007,4,26]],"date-time":"2007-04-26T08:02:57Z","timestamp":1177574577000},"page":"1107-1111","source":"Crossref","is-referenced-by-count":39,"title":["Evolution of Mild Obstructive Sleep Apnea after Different Treatments"],"prefix":"10.1002","volume":"117","author":[{"given":"Johanna","family":"Sahlman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matti","family":"Pukkila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juha","family":"Sepp\u00e4","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henri","family":"Tuomilehto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2009,1,2]]},"reference":[{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199304293281704"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.2109080"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ehj.2004.02.021"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/22.6.749"},{"key":"e_1_2_7_6_2","first-page":"25","volume-title":"Obstructive Sleep Apnea Syndrome: Clinical Research and Treatment","author":"Lugaresi E","year":"1990"},{"key":"e_1_2_7_7_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.52.10.872"},{"key":"e_1_2_7_8_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.104.2.340"},{"key":"e_1_2_7_9_2","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.94.07101765"},{"key":"e_1_2_7_10_2","doi-asserted-by":"publisher","DOI":"10.1053\/rmed.2001.1277"},{"key":"e_1_2_7_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/sleep\/16.suppl_8.S124"},{"key":"e_1_2_7_12_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.16.2013"},{"key":"e_1_2_7_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(98)10532-9"},{"key":"e_1_2_7_14_2","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2004.032078"},{"key":"e_1_2_7_15_2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200311-1571OC"},{"key":"e_1_2_7_16_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.157.3.9709042"},{"key":"e_1_2_7_17_2","first-page":"195","article-title":"Daytime sleepiness and nasal continuous positive airway pressure therapy in obstructive sleep apnea syndrome patients: effects of chronic treatment and 1\u2010night therapy withdrawal.","volume":"18","author":"Sforza E","year":"1995","journal-title":"Sleep"},{"key":"e_1_2_7_18_2","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/147.5.1162"},{"key":"e_1_2_7_19_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.110.1.114"},{"key":"e_1_2_7_20_2","doi-asserted-by":"crossref","unstructured":"SundaramS BridgmanSA LimJ LassersonTJ.Surgery for obstructive sleep apnoea. 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